WO2005063124A1 - Support pourvu d'une pluralite d'elements de perforation, dispositif de perforation et appareil d'analyse de sang - Google Patents

Support pourvu d'une pluralite d'elements de perforation, dispositif de perforation et appareil d'analyse de sang Download PDF

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Publication number
WO2005063124A1
WO2005063124A1 PCT/EP2004/013836 EP2004013836W WO2005063124A1 WO 2005063124 A1 WO2005063124 A1 WO 2005063124A1 EP 2004013836 W EP2004013836 W EP 2004013836W WO 2005063124 A1 WO2005063124 A1 WO 2005063124A1
Authority
WO
WIPO (PCT)
Prior art keywords
carrier
receiving sleeve
blood
lancing
piercing
Prior art date
Application number
PCT/EP2004/013836
Other languages
German (de)
English (en)
Other versions
WO2005063124A8 (fr
Inventor
Armin Lohrengel
Ralf Sprick
Original Assignee
Paul Hartmann Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paul Hartmann Ag filed Critical Paul Hartmann Ag
Priority to EP04803545A priority Critical patent/EP1699355A1/fr
Publication of WO2005063124A1 publication Critical patent/WO2005063124A1/fr
Publication of WO2005063124A8 publication Critical patent/WO2005063124A8/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150435—Specific design of proximal end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/15058—Joining techniques used for protective means
    • A61B5/150587—Joining techniques used for protective means by friction fit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150694—Procedure for removing protection means at the time of piercing
    • A61B5/150725—Procedure for removing protection means at the time of piercing removal procedure linked to further actions, e.g. cocking of the piercing device, which indicate that the piercing device is used or tempered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148—Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15149—Arrangement of piercing elements relative to each other
    • A61B5/15153—Multiple piercing elements stocked in a single compartment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148—Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15157—Geometry of stocking means or arrangement of piercing elements therein
    • A61B5/15159—Piercing elements stocked in or on a disc
    • A61B5/15161—Characterized by propelling the piercing element in a radial direction relative to the disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148—Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15157—Geometry of stocking means or arrangement of piercing elements therein
    • A61B5/15159—Piercing elements stocked in or on a disc
    • A61B5/15163—Characterized by propelling the piercing element in an axial direction relative to the disc
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15146—Devices loaded with multiple lancets simultaneously, e.g. for serial firing without reloading, for example by use of stocking means.
    • A61B5/15148—Constructional features of stocking means, e.g. strip, roll, disc, cartridge, belt or tube
    • A61B5/15176—Stocking means comprising cap, cover, sheath or protection for aseptic stocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B2050/3008—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments having multiple compartments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/20—Holders specially adapted for surgical or diagnostic appliances or instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/33—Trays

Definitions

  • the present invention relates to a carrier with a plurality of lancing elements for use in a blood analysis device or in a lancing device for obtaining a minimal amount of blood from the human or animal body for analysis or examination purposes, for example for determining an analyte, such as, for. B. fructosamine, lactate, cholesterol or in particular glucose.
  • an analyte such as, for. B. fructosamine, lactate, cholesterol or in particular glucose.
  • the invention relates to a lancing device for piercing the body surface to remove a minimal amount of blood from the human or animal body for analysis or examination purposes of the aforementioned type, with a plurality of lancing elements provided on a carrier and insertable with the carrier into a housing body which can be driven by a drive mechanism.
  • the invention relates to a blood analysis device in the form of a so-called "all-in-one" complete device, with a housing body, with a blood sampling device having a plurality of lancing elements, with a plurality of test means for the analysis of a minimal amount of blood, with an evaluation electronics comprehensive evaluation device and with a display device which form a complete system which can be handled as a single device, the housing body having a lancing position assigned to a working position of a respective lancing element for applying a skin surface to a user, a plurality of test means and lancing elements being insertable into the device which can be brought into a working position in order to carry out a plurality of measurements, wherein when a lancing element is positioned in its working position, the lancing element can be inserted into the skin surface of a user applied at the lancing position and blood exiting the skin surface can reach a test medium.
  • Such a blood analyzer is known from WO 03/070099 AI.
  • the object of the present invention is to improve the provision, storage and use of the lancing elements, starting from a carrier of the aforementioned type with a plurality of lancing elements.
  • a respective receiving sleeve delimits an opening, in particular cylindrical, in the axial direction, in which the associated lancing element is received.
  • the opening expediently has a diameter of 2 to 7 mm, in particular 2.5 to 5 mm, in particular 3 to 4.5 mm.
  • the receiving sleeve also expediently has an extension in the axial direction of 6 to 20 mm, in particular of 8 to 15 mm and further in particular of 8 to 14 mm. Furthermore, it proves to be particularly advantageous if a respective lancing element has a molded-on holding body, which at the same time guides the lancing element in the receiving sleeve .
  • a respective lancing element has a preferably molded-on protective cap means.
  • the protective cap means protects the free end of the lancing element, which can be inserted into the skin surface of a user, from contamination and in particular from germs. It can even do one in the course of a spraying process . To effect sterilization of the lancing element in the area of the pierceable tip and to maintain it during storage of the lancing element.
  • the protective cap means closes the receptacle towards the lancing side, in particular it forms a germ-tight seal of the interior of the receptacle.
  • the protective cap means can also advantageously comprise an elastically deformable, in particular elastomeric area or be formed from an elastically deformable, in particular elastomeric material.
  • the cap means passes in one piece via a predetermined breaking area to the holding body '.
  • it can enclose the lancing element over its entire circumference and in particular in a germ-tight manner and preferably bring about a permanent sterile closure.
  • the protective cap means advantageously has a diameter perpendicular to the axial direction of the receiving sleeve of 2 to 7 mm, in particular 2.5 to 5 mm, in particular 3 to 4.5 mm.
  • a respective receiving sleeve for a lancing element simultaneously comprises or holds a test device.
  • the test means is preferably provided in the region of a free end of the receiving sleeve.
  • the test means can be designed, for example, in the form of a membrane defining a measuring field, which can be wetted with a minimal amount of blood taken from the body surface.
  • the test agent includes test reagents that are used to perform an analysis or examination of the blood.
  • test agent or the reaction in the test agent can be carried out, for example, optically, in particular reflecto etrically, or electro-chemically or electro-physically. Evaluation devices and evaluation methods as well as test means of the type that can be used here are known and therefore do not require any further description.
  • test means can advantageously be provided in the form of a pad or tablet and held in the area of the wall or in an opening in the wall of the receiving sleeve.
  • the protective cap means is advantageously designed and arranged such that the test means is covered by the protective cap means before a lancing process is carried out.
  • the test agent can be covered or sealed in a sterile manner on its side that can be subjected to the blood to be examined before the ingress of dirt and moisture, preferably before the ingress of germs and furthermore.
  • the protective cap means can be placed against an axial stop of the receiving sleeve.
  • the receiving sleeve can comprise a stepped opening with a step which forms the stop for the protective cap means.
  • the protective cap means in turn to be provided with a stepped outer periphery and / or a centering means in the broadest sense, which can be placed against the axial end of the receiving sleeve.
  • the lancing element has at least one resilient restoring means, in particular formed integrally with the holding body, which causes or at least supports a restoring movement of the lancing element after the lancing process has been carried out.
  • a resetting means could be realized, for example, in the form of a resilient arm which is molded onto the lancing element, preferably on its holding body, or is formed in one piece with it.
  • Preferably several, in particular three resilient return means are provided.
  • These resetting means can advantageously also be used to stabilize the lancing element within the receiving sleeve before carrying out a lancing process. In particular, they can pretension the lancing element in an axial direction, so that it is forced against a predetermined end position with respect to the receiving sleeve.
  • a pretensioning of the restoring means in the initial state of the lancing element holds the protective cap means in contact with the receiving sleeve, in particular in contact with the above-mentioned axial stop of the receiving sleeve and thus for an improved, preferably germ-tight, closure the receiving sleeve leads.
  • the restoring means mentioned can be supported against or on a section of the receiving sleeve, in particular an annular end section of the receiving sleeve, or it can be supported against a surface of the carrier.
  • a respective receiving sleeve can be inserted into a recess or other holder on the carrier.
  • the carrier can then be equipped with receiving sleeves containing lancing elements for further use in lancing devices or blood analysis devices of the type mentioned at the outset, and can be carried out at a later time and in particular detached from the production of the lancing elements and receiving sleeves. Preference is given to assembly by the manufacturer. In principle, however, it would also be conceivable for the same user to use one and the same carrier several times and to equip each of these with new, unused receiving sleeves with lancing elements.
  • a respective receiving sleeve is held in an open-edged recess in a part of the carrier which is in particular disk-shaped. This creates the possibility that a respective receiving sleeve protrudes in the radial direction over an outer circumferential surface of a part of the carrier and, if necessary, can cooperate there with other adjusting means of a lancing device or a blood analysis device.
  • a respective receiving sleeve is slidably held on the carrier, in particular slidably in the axial or radial direction is held.
  • a receiving sleeve for performing a lancing process can be shifted into an exposed lancing position and, if necessary, can be shifted back into its starting position or another position after the lancing process has been carried out.
  • the receiving sleeves and respective lancing elements can be arranged both axially and radially, that is to say with an axially extending lancing direction or with a radially extending lancing direction of the lancing elements, with respect to a rotatable, that is to say rotatable, carrier.
  • a respective receiving sleeve when the carrier rotates, can be displaced by sliding against a positive guidance means.
  • the positive guidance means can be arranged in a lancing device or a blood analysis device in such a way that when a relevant lancing element with a receiving sleeve is moved into its working position, the receiving sleeve slides against a positive guide means fixed to the housing and this can result in the aforementioned displacement of the receiving sleeve.
  • a respective receiving sleeve has at least one resilient return means which effects or at least supports a return movement of the receiving sleeve, in particular after a lancing process has been carried out.
  • the respective receiving sleeve, together with the lancing element accommodated therein can only be arranged on the carrier in a preferred orientation.
  • the receiving sleeve also holds or carries the test agent. In such a case, it can then be ensured that the test means can be positioned in a predetermined orientation to the wearer and thus in a predetermined orientation to an evaluation device of the type mentioned in a blood analysis device.
  • the receiving sleeve can have a non-circular outer circumference, that is to say which deviates from the circular shape. With a corresponding design of a recess or any other holder for the receiving sleeve on the carrier, it can be achieved that the receiving sleeve can only be arranged on the carrier in a predetermined orientation.
  • the lancing elements have an end portion that can be gripped behind, with which they can be coupled to a drive device within a lancing device or within a blood analysis device for performing the lancing process.
  • This coupling is preferably brought about by the end portions of the lancing elements which can be reached behind being moved into a rear engagement position or coupling position with a correspondingly designed organ of the drive device by displacement, in particular rotation of the carrier, and by further displacement, in particular further rotation of the carrier after carrying out a lancing process out of engagement with the aforementioned Organ of the drive device are brought.
  • the subject of the present invention is also a lancing device for piercing the body surface for taking a minimal amount of blood from the human or animal body for analysis or examination purposes, with a plurality of ones provided on a carrier and with the carrier in a housing body insertable lancing elements by a
  • the lancing device is characterized by a carrier of the design according to the invention described above, that is a carrier according to one or more of claims 1 to 25, which can be used together with the lancing elements in the housing body and can be removed from the housing body again after use of the lancing elements.
  • the invention also relates to a blood analysis device with the features of claim 27, that is to say a blood analysis device which is characterized by a carrier of the design according to the invention described above, that is to say a carrier according to one or more of claims 1 to 25, which together with the lancing elements in the housing body can be used and can be removed from the housing body after use of the lancing elements.
  • FIG. 1 shows a perspective view of an embodiment of a blood analysis device according to the invention
  • Figure 2 is a perspective view of the blood analyzer of Figure 1 in half-torn shape
  • Figure 3 is a sectional view of the blood analyzer of Figures 1 and 2 seen in the direction of the arrows Hill I in Figure 1;
  • Figure 4a is an exploded view of a gear section of the blood analyzer according to the invention;
  • Figure 4b is a perspective view of the gear section of Figure 4a torn in half;
  • FIG. 5a shows a perspective view of an impact mechanism of the blood analysis device according to the invention (without other further components);
  • Figure 5b is a sectional view of the impact mechanism of Figure 5a;
  • 6a-d show three views and a sectional view of a lancing element accommodated in an accommodating sleeve
  • Figure 7a-d four views of a lancing element received in a receiving sleeve in cooperation with a lower region of the push mechanism
  • FIG. 8 a-c show a perspective view, a top view and a sectional view of a carrier for a plurality of lancing elements
  • FIG. 9 shows a perspective view of a further embodiment of a blood analysis device according to the invention.
  • Figure 10 is a side view of the blood analyzer of Figure 9 and
  • FIG 11 is a perspective view of a carrier with radially arranged lancing elements.
  • a blood analyzer designated as a whole by reference number 2 can be seen from FIGS. 1 to 3. It comprises a housing body 4 with a display device 6 for displaying the result of the analysis or examination of a minimal amount of blood.
  • the blood analysis device 2 also includes an integrated blood sampling device, designated overall by the reference numeral 8, which interacts with a plurality of lancing elements 10, which are able to penetrate a skin surface of a user applied to a lancing position 12 quickly and as painlessly as possible in order to obtain a minimal amount of blood , Blood emerging from the skin surface wets a test agent 14, in which an analysis or test reaction takes place, which can be evaluated by means of an evaluation device (not shown).
  • the evaluation device can be an optically acting or electrochemically or electro-physically acting evaluation device, by means of which a test or analysis reaction which takes place in the test means can be recorded and evaluated, which is known per se and is therefore not described in more detail here.
  • the evaluation device can interact with the test device in the lancing position 12 shown or in another position within the blood analysis device 2.
  • the test means 14 shown in FIGS. 2 and 3 is brought into a different position by rotating a carrier 16 for lancing elements 10 and test means 14 to be described in more detail, where the test means 14 directly with the evaluation device, not shown can work together.
  • the blood collection device 8 When the blood collection device 8 is put into operation, it is inside the housing body 4 and thus also in the area of the
  • Lancing position 12 generates a negative pressure. There is one for this
  • Vacuum generating device 18 is provided which Volume-changeable area 20, which is limited by a bellows 22.
  • the vacuum generating device 18 can be actuated by finger pressure on a printer 24. In the course of the low pressure of the printer 24, air is displaced outward from the volume-variable region 20 and the housing body 4. During the subsequent releasing, a vacuum is generated under the action of a first spring 26 in the interior of the volume-variable region 20 and thus in the interior of the housing body 4.
  • a rotary movement is generated at the same time via a gear device 28, which will be described in detail, and which is applied to the carrier 16 for a plurality of at least 4, in particular at least 6, in particular at least 8, in particular at least 10, and further transmitted in particular by at least 12 lancing elements 10 and a corresponding number of test means 14 in order to bring a new, still unused lancing element 10 and associated test means 14 m into the working position 30 assigned to the lancing position 12.
  • a coupling mechanism 32 of the blood collection device 8 is tensioned via a coupling device 32 to be described in more detail with a Bowden cable 34.
  • Bowden cable 34 is moved under the action of a third spring 38 m in the direction of arrow 40.
  • a drive lever 42 protruding to the side from the Bowden cable 34 is displaced 8 m in the direction of arrow 46 with the aid of a tensioning means 44 for a pull wire of the drive mechanism 36 of the blood collection device.
  • the driving lever 42 can be fixed in the tensioned state with an engaging end 48 m of a locking device 50.
  • the clamping means 44 is released the pulling wire and the pulling wire snap under the action of spring means to be described in more detail in the direction of the working position 30 and drives a lancing element 10 arranged there to carry out the lancing process.
  • the negative pressure prevailing in the area of the lancing position 12 supports the extraction of a minimum amount of blood from the surface of the skin and also supports the transport of the minimum amount of blood to the test means 14.
  • the lancing element 10 just used is removed from its working position 30 together with brought to the test means 14, and the test means 14 is brought into a working position for interaction with the evaluation device (not shown), where the test reaction of the blood with the test means 14 is then evaluated optically, electro-physically or electro-chemically.
  • the gear device 28 for converting an axial actuating movement into a rotary movement is explained below in conjunction with FIGS. 4a, 4b and 3.
  • the gear device 28 comprises a guide bush 52 fixed to the housing, in which a pressure piece 54 can be displaced to a limited extent by a step stop 55.
  • the pusher 24 is pressed in at the free end of the pressure piece 54.
  • a shaft section 56 engages with a spur toothing 58, which spur toothing 58 cooperates with a spur toothing 60 of the pressure piece 54 facing it.
  • the shaft section 56 is prestressed in the direction of the pressure piece 54 by a second spring 62.
  • the shaft section 56 comprises on its outer surface a plurality of radially projecting and longitudinally extending webs 64, which engage in longitudinal grooves 66 in the interior of the fixed guide bush 52 and prevent the shaft section 56 from rotating relative to the guide bush 52 while maintaining axial displaceability.
  • the pressure piece 54 is moved axially, its spur gear teeth 60 interacting with the spur gear teeth 58 of the shaft section 56 and thereby generating a rotational driving force.
  • a rotational movement is prevented by engagement of the webs 64 in the longitudinal grooves 66, so that the shaft section 56 is also moved axially, contrary to the action of the second spring 62, and downwards in the illustration in FIG. 3.
  • an incremental rotational movement of the shaft section 56 corresponding to the spur toothing is generated, which is ended by a positive engagement of the spur toothing 58 and 60 in one another.
  • a new, unused lancing element 10 is brought into its working position 30.
  • a push member 78 which can be releasably connected to an engaging head section 76 of the lancing member 10.
  • the push member 78 is biased in the pushing direction against a housing-fixed wall section 82 via a fifth spring 80. It comprises an axial opening 84 through which a semi-rigid pulling wire 86 extends into a cylindrical cavity 88 of the pushing element 78 and is biased there in the pushing direction by means of a sixth spring 90.
  • the semi-rigid puller wire 86 extends through an opening in the wall section 82 and further through a tensioning means 44 consisting of a clamping cone 92 and a clamping device 94 and further through an opening in the driving lever 42.
  • the clamping cone 92 In the released state of the clamping device 94, the clamping cone 92 is movable with respect to the pull wire 86. It is axially limitedly movable with respect to the driving lever 42 in such a way that when the driving lever 42 is adjusted, its persistence or frictional forces between the clamping cone 92 and a cylinder wall surrounding it cause clamping or release of the pull wire 86 in the clamping device 94.
  • Locking device 50 the graspable end 48 of the driving lever 42 is fixed.
  • the tensioning process described above takes place against the spring force of the fifth spring 80, which stores the impact energy required for the drive mechanism 36.
  • the locking device 50 is released by actuating a trigger 96, that is to say the rear end 48 of the driving lever 42 is released, then the persistence of the Clamping cone 92 that the clamping device 94 releases the pull wire 86.
  • the thrust member 78 and with it the puller wire 86 then snap down under the action of the fifth spring 80. Due to the coupling of the pushing element 78 and the lancing element 10, the lancing element 10 then carries out a lancing process. It snaps over the free end of a receptacle 98 to be described in more detail and is pulled back again behind the free end.
  • a respective lancing element 10 which is a metallic needle-shaped element with a length of 6-15 mm, has a molded-on holding body 100 and also a molded-on protective cap means 102, which protects the lancing element 10 against contamination and a preferably germ-tight, preferably sterile Ensures closure against the environment.
  • a respective lancing element 10 with holding body 100 and protective cap means 102 is accommodated in a receiving sleeve 98 which has already been mentioned and is displaceable in the axial direction.
  • the lancing element 10 is inserted with its engaging head portion 76 into the opening at the free end 104 of the receiving sleeve 98 and passed through the receiving sleeve 98 until the protective cap means 102 abuts an axial step 106 inside the preferably cylindrical opening 107 of the receiving sleeve 98.
  • a resilient return means 108 can also be seen in the figures, the resilient arms 110, which can be integrally formed on the holding body 100, rest on a collar-like section 112 of the receiving sleeve 98. When a lancing process is carried out, these restoring means 108 cause the lancing element 10 to be pulled back again behind the end 104 of the receiving sleeve 98.
  • the pretensioning of the resetting means 108 in the initial state of the lancing element 10 can also be used to hold the protective cap means 102 in contact with the receiving sleeve 98, to hold in particular in contact with the axial stop 106 of the receiving sleeve 98 and thus to bring about an improved, preferably germ-tight closure of the receiving sleeve 98.
  • FIGS. 7a to d illustrate how the head section 76, which can be formed in particular in one piece with the molded-on holding body 100, is positively gripped or gripped behind in a groove 114 of the pushing element 78 which can be gripped behind.
  • the pressing element 78 cooperates with a molded-on ramp means 116, which also forms an apparent from Figure 7b insertion opening 118 for the 'head portion 76 of the lancing element 10th
  • This ramp means 116 acts with a run-on slope 120, which is formed on the annular collar section 112 of the receiving sleeve 98.
  • the run-up slope 120 slides against the ramp means 116 and the entire receiving sleeve 98 is axially moved in the direction of the arrow 122. Due to the positive engagement of the head section 76 of the lancing element 10 in the groove 114 of the pushing element 78, the lancing element is held in its original axial position, so that it does not carry out the axial movement in the direction of arrow 122. The lancing element 110 is therefore withdrawn relative to the receiving sleeve 98. As a result, the protective cap means 102 is released from the free end of the lancing element 10. It can fall down.
  • the blood collection device 8 is then ready to perform a lancing process.
  • the protective cap means 102 is removed, the test means 14 is also released, which is advantageously received in the region of the free end 104 of the receiving sleeve 98.
  • the test means 14 can be provided in an opening in the wall of the receiving sleeve 98.
  • the test means is covered on the inside by the protective cap means 102 and in this way before Contamination, in particular protected from the ingress of air humidity and germs, which is to be regarded as particularly advantageous.
  • the protective cap means 102 thus performs a double function, it serves both to cover the lancing element 10 and to cover and protect the test means 14.
  • FIGS. 6 and 7 also show helical webs on the outer circumference of the receiving sleeve 98.
  • These are spring-back means 124 which are molded onto the collar-shaped section 112 at their upper end. If the carrier 16 is moved further and the receiving sleeve 98 just considered is thereby moved out of its working position 30 and thus out of the influence of the ramp means 116, these spring-back means 124 cause the receiving sleeve 98 to be withdrawn again against the arrow 122.
  • FIGS. 8a to c show the carrier 16 for the plurality of lancing elements 10 and test means 14 in different views.
  • twelve receiving sleeves 98 with twelve lancing elements 10 and twelve test means 14 are received.
  • a respective receiving sleeve 98 is inserted into an open-edged recess 126 of a disk-shaped part 128 of the carrier 16 in the axial direction. So that the receiving sleeves 98 cannot twist in their working position 30 when interacting with the ramp means 116, the open-edged recesses 126 and the outer circumference of the receiving sleeves 98 are non-circular, in the case shown being slightly elliptical.
  • a respective receiving sleeve 98 is held in a preferred orientation on the carrier 16, which is very important with regard to the positioning of the test means 14 received in the receiving sleeve 98, because it is at a predetermined position and orientation interact with the evaluation device must be able to.
  • the carrier 16 with a centrally arranged polygonal opening 130 for the engagement of an appropriately designed hub section 74 for the rotary drive of the carrier can be inserted together with the lancing elements 10 and test means 14 in the housing body 4 of the blood analysis device according to the invention and together with the used lancing elements and test means removable from the housing body. This can be seen from FIG. 2, where a cover which exposes or closes the insertion opening is provided.
  • FIGS. 9-11 show a further embodiment of a blood analysis device according to the invention, in which the lancing direction and the lancing elements themselves are arranged radially with respect to a carrier for the lancing elements which can be driven in rotation.
  • a drive device (not shown) for the lancing elements is provided radially inside the carrier.
  • the pusher 24 is depressed for the first time against the tension force of the first spring 26 and the second spring 62.
  • the pressure piece 54 and the shaft section 56 are thereby displaced axially downward.
  • a force is built up in the circumferential direction of rotation.
  • the construction train 34 releases the driving lever 42, which moves under the pressure of the third spring 38 in the direction of the arrow 40.
  • the puller wire 86 is clamped in the clamping device 94 and thus the puller wire 86 is also pulled upwards.
  • the impact member 78 still remains in its starting position.
  • the webs 64 come free from the longitudinal grooves 66 of the fixed guide bush 52 and the shaft section can carry out a rotational movement of 15 °.
  • the carrier is moved further by 15 ° via the pair of gearwheels 70, 72 and brings a lancing element 10 into the working position 30.
  • the head section 76 of the lancing element 10 slides into the opening 114 of the pushing element 78 and thus into the rear grip position.
  • the receiving sleeve 98 slides against the ramp means 116 with its chamfer 120 and is moved downward in the direction of the arrow 122, so that the protective cap means 102 is released from the lancing element 10.
  • the vacuum generating device 18 is now activated and the drive mechanism 36 of the blood collection device 8 is cocked.
  • the trigger 96 By actuating the trigger 96, the locking device 50 can be released, and thus the thrust member 78 shoots down under the force of the fifth spring 80 and the lancing process is carried out.
  • the pusher 24 is reset under the force of the first spring 26 and the second spring 62.
  • the volume-changeable region 20 is enlarged and a negative pressure is generated which extends to the lancing position 12 in the region of the free end 104 of the receiving sleeve 98 and supports and promotes blood withdrawal.
  • the fourth spring and the sixth spring 90 push the pushing element 78 back into its starting position and thus bring about the retraction movement of the lancing element 10, which is also supported by the resilience means 124.
  • the lancing element 10 just considered, together with its receiving sleeve 98 and the test means 14 is then rotated by a further 15 °; it is therefore removed from the working position 30 of the lancing elements.
  • the stroke of the pusher 24 is limited in this second actuation by a suitable design of the transmission device 28, so that the drive device 36 is not tensioned.
  • the test means 14 can thus be transported on to an optical, electro-chemical or electro-physical acting evaluation device, not shown.
  • the predetermined positioning of the receiving sleeves 98 on the carrier 16 ensures that the test means are arranged in the correct orientation to the evaluation device.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Geometry (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un support comportant une pluralité d'éléments de perforation, à utiliser dans un appareil d'analyse de sang ou dans un dispositif de perforation pour extraire une quantité minimale de sang du corps d'un homme ou d'un animal à des fins d'analyse ou d'examen, chaque élément de perforation étant logé respectivement dans une douille de réception où il peut se déplacer.
PCT/EP2004/013836 2003-12-23 2004-12-06 Support pourvu d'une pluralite d'elements de perforation, dispositif de perforation et appareil d'analyse de sang WO2005063124A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04803545A EP1699355A1 (fr) 2003-12-23 2004-12-06 Support pourvu d'une pluralite d'elements de perforation, dispositif de perforation et appareil d'analyse de sang

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10361560A DE10361560A1 (de) 2003-12-23 2003-12-23 Träger mit einer Mehrzahl von Stechelementen, Stechvorrichtung und Blutanalysegerät
DE10361562A DE10361562A1 (de) 2003-12-23 2003-12-23 Blutanalysegerät zur Bestimmung eines Analyten
DE10361560.1 2003-12-23

Publications (2)

Publication Number Publication Date
WO2005063124A1 true WO2005063124A1 (fr) 2005-07-14
WO2005063124A8 WO2005063124A8 (fr) 2005-09-22

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ID=55970600

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2004/013825 WO2005065545A2 (fr) 2003-12-23 2004-12-04 Appareil d'analyse de sang servant a determiner la presence d'une substance a analyser
PCT/EP2004/013836 WO2005063124A1 (fr) 2003-12-23 2004-12-06 Support pourvu d'une pluralite d'elements de perforation, dispositif de perforation et appareil d'analyse de sang

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Application Number Title Priority Date Filing Date
PCT/EP2004/013825 WO2005065545A2 (fr) 2003-12-23 2004-12-04 Appareil d'analyse de sang servant a determiner la presence d'une substance a analyser

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EP (2) EP1699356A2 (fr)
DE (2) DE10361562A1 (fr)
WO (2) WO2005065545A2 (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
ES2335576T3 (es) 2001-06-12 2010-03-30 Pelikan Technologies Inc. Aparato y procedimiento de toma de muestras de sangre.
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
ATE497731T1 (de) 2001-06-12 2011-02-15 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
WO2002100460A2 (fr) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Actionneur electrique de lancette
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004107964A2 (fr) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Procede et appareil d'echantillonnage de fluides anatomiques et d'examen de l'analysat
WO2006001797A1 (fr) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Element penetrant peu douloureux
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (fr) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Procédé et appareil permettant d'améliorer le flux fluidique et le prélèvement d'échantillons
WO2006011062A2 (fr) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Hydrogel imprimable pour biocapteurs
WO2005120365A1 (fr) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Procede et appareil pour la fabrication d'un dispositif d'echantillonnage de liquides
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP2265324B1 (fr) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Système intégré de mesure d'analytes
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794926A (en) * 1986-11-24 1989-01-03 Invictus, Inc. Lancet cartridge
EP0877250A2 (fr) * 1997-04-28 1998-11-11 Bayer Corporation Dispositif de distribution pour des détecteurs de contrÔle de fluides
DE10057832C1 (de) * 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
WO2003070099A1 (fr) * 2002-02-21 2003-08-28 Facet Technologies, Llc Analyseur de sang et dispositif de piqure utilisables en analyse du sang
US20040049219A1 (en) * 2002-04-19 2004-03-11 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4627445A (en) * 1985-04-08 1986-12-09 Garid, Inc. Glucose medical monitoring system
EP0798004A1 (fr) * 1996-03-29 1997-10-01 Wagner, Wolfgang, Dr.med. Dispositif et méthode associée pour la commande du métabolisme d'un corps vivant
US5951492A (en) * 1996-05-17 1999-09-14 Mercury Diagnostics, Inc. Methods and apparatus for sampling and analyzing body fluid
US6027459A (en) * 1996-12-06 2000-02-22 Abbott Laboratories Method and apparatus for obtaining blood for diagnostic tests
US6132449A (en) * 1999-03-08 2000-10-17 Agilent Technologies, Inc. Extraction and transportation of blood for analysis
US6152942A (en) * 1999-06-14 2000-11-28 Bayer Corporation Vacuum assisted lancing device
DK1328192T3 (da) * 2001-03-29 2011-03-28 Lifescan Scotland Ltd Integreret blodprøvemåleapparat
US7025774B2 (en) * 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
GB2388898B (en) * 2002-04-02 2005-10-05 Inverness Medical Ltd Integrated sample testing meter
US7060192B2 (en) * 2002-05-09 2006-06-13 Lifescan, Inc. Methods of fabricating physiological sample collection devices

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794926A (en) * 1986-11-24 1989-01-03 Invictus, Inc. Lancet cartridge
EP0877250A2 (fr) * 1997-04-28 1998-11-11 Bayer Corporation Dispositif de distribution pour des détecteurs de contrÔle de fluides
DE10057832C1 (de) * 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
WO2003070099A1 (fr) * 2002-02-21 2003-08-28 Facet Technologies, Llc Analyseur de sang et dispositif de piqure utilisables en analyse du sang
US20040049219A1 (en) * 2002-04-19 2004-03-11 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation

Also Published As

Publication number Publication date
EP1699355A1 (fr) 2006-09-13
WO2005065545A3 (fr) 2005-10-27
DE10361560A1 (de) 2005-07-28
EP1699356A2 (fr) 2006-09-13
DE10361562A1 (de) 2005-07-28
WO2005063124A8 (fr) 2005-09-22
WO2005065545A2 (fr) 2005-07-21

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