WO2005045850A3 - Radioaktives arsentriiodid und dessen verwendung zur radioaktiven markierung - Google Patents
Radioaktives arsentriiodid und dessen verwendung zur radioaktiven markierung Download PDFInfo
- Publication number
- WO2005045850A3 WO2005045850A3 PCT/EP2004/011799 EP2004011799W WO2005045850A3 WO 2005045850 A3 WO2005045850 A3 WO 2005045850A3 EP 2004011799 W EP2004011799 W EP 2004011799W WO 2005045850 A3 WO2005045850 A3 WO 2005045850A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- radioactive
- markings
- arsenic
- marked
- arsenic triiodide
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G4/00—Radioactive sources
- G21G4/04—Radioactive sources other than neutron sources
- G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
- G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/02—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes in nuclear reactors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Plasma & Fusion (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
Beschrieben ist radioaktives Arsentriiodid der Formel *Asl3, wobei * für 70, 71, 72, 74, 76 oder 77 steht, sowie ein Verfahren zur radioaktiven Markierung organischer Verbindungen, wobei mindestens eine reaktive Gruppe in den zu markierenden Verbindungen mit dem Arsen(III)halogenid unter Ausbildung einer kovalenten Bindung reagiert. Die zu markierende Verbindung ist vorzugsweise eine Aminosäure, ein Peptid oder ein Protein. Sie enthält vorzugsweise Mercaptogruppen und/oder primäre Aminogruppen. Gegebenenfalls wird sie auf bekannte Weise chemisch so modifiziert, daß geeignete Bindungsstellen entstehen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2003150397 DE10350397A1 (de) | 2003-10-28 | 2003-10-28 | Radioaktives Arsentriiodid und dessen Verwendung zur radioaktiven Markierung |
DE10350397.8 | 2003-10-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2005045850A2 WO2005045850A2 (de) | 2005-05-19 |
WO2005045850A3 true WO2005045850A3 (de) | 2006-02-16 |
Family
ID=34559227
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2004/011799 WO2005045850A2 (de) | 2003-10-28 | 2004-10-19 | Radioaktives arsentriiodid und dessen verwendung zur radioaktiven markierung |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE10350397A1 (de) |
WO (1) | WO2005045850A2 (de) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997002246A1 (en) * | 1995-07-06 | 1997-01-23 | Research Corporation Technologies, Inc. | (aminostyryl)pyridinium compounds for radiolabelling cell membranes |
US6106804A (en) * | 1997-06-13 | 2000-08-22 | The University Of New Mexico | Arsenic-72 labeled compounds for tissue specific medical imaging |
-
2003
- 2003-10-28 DE DE2003150397 patent/DE10350397A1/de not_active Withdrawn
-
2004
- 2004-10-19 WO PCT/EP2004/011799 patent/WO2005045850A2/de active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997002246A1 (en) * | 1995-07-06 | 1997-01-23 | Research Corporation Technologies, Inc. | (aminostyryl)pyridinium compounds for radiolabelling cell membranes |
US6106804A (en) * | 1997-06-13 | 2000-08-22 | The University Of New Mexico | Arsenic-72 labeled compounds for tissue specific medical imaging |
Non-Patent Citations (3)
Title |
---|
BILLINGHURST M W ET AL: "Separation of radioarsenic from a germanium dioxide target", APPLIED RADIATION AND ISOTOPES UK, vol. 41, no. 5, 1990, pages 501 - 507, XP008054863, ISSN: 0883-2889 * |
M. JENNEWEIN ET AL.: "A NEW 72SE/72AS ISOTOPE GENERATOR BASED ON SOLID PHASE EXTRACTION", JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS, vol. 46, no. s1, August 2003 (2003-08-01), pages S403, XP002351640 * |
WATTERS H F ET AL: "The radionuclides of arsenic produced by deuteron bombardment of germanium", PHYSICAL REVIEW USA, vol. 92, 1 December 1953 (1953-12-01), pages 1248 - 1249, XP002351641 * |
Also Published As
Publication number | Publication date |
---|---|
DE10350397A1 (de) | 2005-06-16 |
WO2005045850A2 (de) | 2005-05-19 |
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