WO2005021790A3 - Use of gene sequences specific for mycobacterium tuberculosis and their related proteins for diagnosis and prevention of tubercular infection - Google Patents

Use of gene sequences specific for mycobacterium tuberculosis and their related proteins for diagnosis and prevention of tubercular infection Download PDF

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Publication number
WO2005021790A3
WO2005021790A3 PCT/IT2004/000471 IT2004000471W WO2005021790A3 WO 2005021790 A3 WO2005021790 A3 WO 2005021790A3 IT 2004000471 W IT2004000471 W IT 2004000471W WO 2005021790 A3 WO2005021790 A3 WO 2005021790A3
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WO
WIPO (PCT)
Prior art keywords
diagnosis
prevention
mycobacterium tuberculosis
gene sequences
sequences specific
Prior art date
Application number
PCT/IT2004/000471
Other languages
French (fr)
Other versions
WO2005021790A2 (en
Inventor
Giulia Cappelli
Francesca Mariani
Vittorio Colizzi
Original Assignee
Consiglio Nazionale Ricerche
Giulia Cappelli
Francesca Mariani
Vittorio Colizzi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Consiglio Nazionale Ricerche, Giulia Cappelli, Francesca Mariani, Vittorio Colizzi filed Critical Consiglio Nazionale Ricerche
Publication of WO2005021790A2 publication Critical patent/WO2005021790A2/en
Publication of WO2005021790A3 publication Critical patent/WO2005021790A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to the use of gene sequences specific Mycobacterium tuberculosis and their corresponding proteins for the diagnosis and the prevention of the tubercular infection.
PCT/IT2004/000471 2003-08-29 2004-08-25 Use of gene sequences specific for mycobacterium tuberculosis and their related proteins for diagnosis and prevention of tubercular infection WO2005021790A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2003A000411 2003-08-29
IT000411A ITRM20030411A1 (en) 2003-08-29 2003-08-29 USE OF SPECIFIC GENE SEQUENCES OF MYCOBACTERIUM TUBERCOLOSIS IN ADDITIONAL PROTEINS FOR DIAGNOSIS AND PREVENTION OF TUBERCULAR INFECTION.

Publications (2)

Publication Number Publication Date
WO2005021790A2 WO2005021790A2 (en) 2005-03-10
WO2005021790A3 true WO2005021790A3 (en) 2005-05-06

Family

ID=30131558

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2004/000471 WO2005021790A2 (en) 2003-08-29 2004-08-25 Use of gene sequences specific for mycobacterium tuberculosis and their related proteins for diagnosis and prevention of tubercular infection

Country Status (2)

Country Link
IT (1) ITRM20030411A1 (en)
WO (1) WO2005021790A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103589676A (en) * 2013-11-14 2014-02-19 复旦大学 rBCG (recombinant bacillus Calmette-Guerin):: Rv3425
JP7314358B2 (en) 2010-07-23 2023-07-25 セレスティス リミテッド Use of amino acid sequences from Mycobacterium tuberculosis or their corresponding nucleic acids for the diagnosis and prevention of tuberculosis infection, and diagnostic kits and vaccines derived therefrom

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2397852B1 (en) 2006-03-14 2013-12-04 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
CN100395342C (en) * 2006-06-22 2008-06-18 复旦大学 Recombinant Ag85B-Rv3425 bacillus Calmette-Guerin vaccine
CN103063843A (en) * 2011-10-20 2013-04-24 上海交通大学医学院 Specific marker of mycobacterium tuberculosis and application thereof
CN106237317A (en) * 2015-06-15 2016-12-21 复旦大学 The Vaccinum Calmette-Guerini being made up of antigen of mycobacterium tuberculosis
CN106093420B (en) * 2016-05-30 2017-09-29 南华大学 A kind of ELISA kit for tuberculosis serological diagnosis
CN106011296B (en) * 2016-08-01 2019-10-25 武汉大学 A kind of mycobacterium tuberculosis Rv1768 gene droplet digital pcr absolute quantitation detection kit

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996025519A1 (en) * 1995-02-17 1996-08-22 Pathogenesis Corporation Virulence-attenuating genetic deletions
WO1999054487A2 (en) * 1998-04-16 1999-10-28 Institut Pasteur A method for isolating a polynucleotide of interest from the genome of a mycobacterium using a bac-based dna library. application to the detection of mycobacteria
US6294328B1 (en) * 1998-06-24 2001-09-25 The Institute For Genomic Research DNA sequences for strain analysis in Mycobacterium tuberculosis
WO2002044406A2 (en) * 2000-11-28 2002-06-06 Health Protection Agency Projection against mycobacterial infections
US20020176873A1 (en) * 1998-08-25 2002-11-28 Marcel Behr Molecular differences between species of the M. tuberculosis complex
WO2003018053A1 (en) * 2001-08-22 2003-03-06 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccine against mycobacterial-induced diseases

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996025519A1 (en) * 1995-02-17 1996-08-22 Pathogenesis Corporation Virulence-attenuating genetic deletions
WO1999054487A2 (en) * 1998-04-16 1999-10-28 Institut Pasteur A method for isolating a polynucleotide of interest from the genome of a mycobacterium using a bac-based dna library. application to the detection of mycobacteria
US6294328B1 (en) * 1998-06-24 2001-09-25 The Institute For Genomic Research DNA sequences for strain analysis in Mycobacterium tuberculosis
US20020176873A1 (en) * 1998-08-25 2002-11-28 Marcel Behr Molecular differences between species of the M. tuberculosis complex
WO2002044406A2 (en) * 2000-11-28 2002-06-06 Health Protection Agency Projection against mycobacterial infections
WO2003018053A1 (en) * 2001-08-22 2003-03-06 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccine against mycobacterial-induced diseases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BEHR M A ET AL: "Comparative genomics of BCG vaccines by whole-genome DNA microarray", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 284, no. 5419, 28 May 1999 (1999-05-28), pages 1520 - 1523, XP002200574, ISSN: 0036-8075 *
BROSCH ET AL: "USE OF A MYCOBACTERIUM TUBERCULOSIS H37Rv BACTERIAL ARTIFICIAL CHROMOSOME LIBRARY FOR GENOME MAPPING, SEQUENCING, AND COMPARATIVE GENOMICS", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 66, no. 5, May 1998 (1998-05-01), pages 2221 - 2229, XP002104659, ISSN: 0019-9567 *
MAHAIRAS G G ET AL: "MOLECULAR ANALYSIS OF GENETIC DIFFERENCES BETWEEN MYCOBACTERIUM BOVIS BCG AND VIRULENT M. BOVIS", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 178, no. 5, 1 March 1996 (1996-03-01), pages 1274 - 1282, XP000647583, ISSN: 0021-9193 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7314358B2 (en) 2010-07-23 2023-07-25 セレスティス リミテッド Use of amino acid sequences from Mycobacterium tuberculosis or their corresponding nucleic acids for the diagnosis and prevention of tuberculosis infection, and diagnostic kits and vaccines derived therefrom
CN108642194B (en) * 2010-07-23 2024-05-17 塞尔雷斯蒂斯有限公司 Use of amino acid sequences or corresponding nucleic acids for diagnosis and prevention of tuberculosis infection
CN103589676A (en) * 2013-11-14 2014-02-19 复旦大学 rBCG (recombinant bacillus Calmette-Guerin):: Rv3425
CN103589676B (en) * 2013-11-14 2015-07-29 复旦大学 A kind of recombinant bacillus Calmette-Guerin vaccine rBCG::Rv3425

Also Published As

Publication number Publication date
ITRM20030411A1 (en) 2005-02-28
ITRM20030411A0 (en) 2003-08-29
WO2005021790A2 (en) 2005-03-10

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