WO2004096658A1 - Contenant a dessus de couvercle rabattable a siccatif integre - Google Patents

Contenant a dessus de couvercle rabattable a siccatif integre Download PDF

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Publication number
WO2004096658A1
WO2004096658A1 PCT/IB2004/001335 IB2004001335W WO2004096658A1 WO 2004096658 A1 WO2004096658 A1 WO 2004096658A1 IB 2004001335 W IB2004001335 W IB 2004001335W WO 2004096658 A1 WO2004096658 A1 WO 2004096658A1
Authority
WO
WIPO (PCT)
Prior art keywords
cap
container
package
sieve
wall
Prior art date
Application number
PCT/IB2004/001335
Other languages
English (en)
Inventor
Rajiv Malik
Santanu Chowdhury
Nidhi Aggarwal
Indranath Sengupta
Golukonda Prasanna Kumar
Original Assignee
Ranbaxy Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Limited filed Critical Ranbaxy Laboratories Limited
Priority to EP04730611A priority Critical patent/EP1638856A1/fr
Publication of WO2004096658A1 publication Critical patent/WO2004096658A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D43/00—Lids or covers for rigid or semi-rigid containers
    • B65D43/14—Non-removable lids or covers
    • B65D43/16—Non-removable lids or covers hinged for upward or downward movement
    • B65D43/162—Non-removable lids or covers hinged for upward or downward movement the container, the lid and the hinge being made of one piece
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/30—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials for desiccators

Definitions

  • the present invention relates to a package that includes a body and flip-top cap with a built-in component for a desiccant.
  • the invention particularly relates to packages for moisture sensitive materials, particularly pharmaceutical substances.
  • the containment of a product is a fundamental function of packaging for medicinal products, as well as food products.
  • the design of high-quality packaging must take into account both the needs of the products and of the manufacturing and distribution system.
  • the packaging Apart from being strong, inert, and leak-proof, the packaging must provide protection of the product against all adverse external variables that may affect a products quality or potency. These variables include light, moisture, oxygen, biological contamination and mechanical damage.
  • Moisture control during the initial placement of substances into sealed, moisture- free containers is usually manageable.
  • the container should be selected so that it has a low permeability to moisture; such a selection also is usually manageable.
  • the product is protected from moisture until it reaches the end user.
  • the container is repeatedly opened and closed to access the product. Each time the container is opened moisture will be introduced into the container. Unless this moisture is removed from the container, it may be detrimentally absorbed by the product. For this reason, it is a well known practice to include a desiccating unit together with the product in the container.
  • a small sachet, bag or pouch may contain the desiccating material and be placed into the container. Problems may arise when the desiccant is loose and comes in direct contact with the product, is unknowingly ingested by the consumer or is accidentally thrown away or otherwise lost.
  • U.S. Patent No. 5,114,003 discloses a container in which the desiccant canister is secured to the inside at the base of the container and the desiccant canister is punctured immediately prior to use.
  • Sud-Chemie Performance packaging markets desiccant filled plastic inserts that can be easily placed into screw or bottle container caps.
  • Desiccants have also been integrated into product packaging.
  • Capital Specialty Plastics has developed vials and containers having desiccant linings that are airtight and leak proof.
  • Sanner provides closures equipped with highly active adsorbents for moisture protection, as well as spaces for protection from damage during transportation.
  • U.S. Patent No. 5,348,201 and U.S. Patent No. 5,417,350 disclose flip top closure devices for a dispensing opening of a container.
  • the closure devices have a first body member with a flip top adapted to be mounted on the container and a second body member mounted on the first body member.
  • U.S. Patent No. 5,992,659 discloses a tamper evident flip top pouring closure for use with a container having a neck with an opening.
  • the neck also has an outer surface with a screw thread and interlocking means thereon.
  • the inventors have now designed an improved package for moisture-sensitive products, that includes a flip-top cap with a built in desiccant. Summary of the Invention
  • a package for containing materials that require a substantially moisture-free environment includes a container, a flip-top cap, a hinge joining the container and the cap, and a sieve.
  • the flip-top cap has an inner side, an outer side, and a wall extending from the inner side.
  • the inner side and the wall define a compartment.
  • the sieve includes a perforated top and a wall extending from the perforated top, the sieve being configured to be mounted to the wall extending from the inner side to retain at least a desiccant material in the compartment.
  • Embodiments of the package may include one or more of the following features.
  • the hinge may be integral with the container and the cap.
  • the hinge may not be integral with either or both of the container and the cap.
  • the cap may be press-fitted into an opening of the container to provide an air-tight environment.
  • the sieve may be snap-fitted on the wall extending from the inner side.
  • the hinge may be integral with the container and the cap.
  • the package may further include an extending member on the cap, the extending member extending from the cap such that the extending member can function as a lever to open the cap.
  • the package may further include at least one desiccant within the compartment.
  • the desiccant may be one or more of montmorillonite clay, silica gel, molecular sieve, calcium oxide, calcium sulphate and calcium chloride.
  • the sieve may be a high density polyethylene.
  • the container may be made of one or more of polyolefms and elastomers.
  • the container and cap may be manufactured by injection molding.
  • the container may have a differential wall thickness across the cross- section.
  • the wall extending from the inner side of the cap may include at least one detent.
  • the sieve includes the perforated top, the wall extending from the perforated top, and may include at least one detent extending from the wall. Mounting the sieve to the cap includes forming an interference fit between the detents and the opposite walls.
  • the package may further include tamper-evident packaging.
  • the tamper-evident packaging may be heat shrink wrappers and film wrappers.
  • a process of making a package for containing materials that require a substantially moisture-free environment includes forming a container; forming a flip-top cap having an inner side, an outer side, and a wall extending from the inner side, the inner side and the wall defining a compartment; forming a hinge joining the container and the cap; and forming a sieve comprising a perforated top and a wall extending from the top.
  • the sieve is configured to be mounted to the wall extending from the inner side to retain at least a desiccant material in the compartment.
  • Embodiments of the process may include one or more of the following features or those described above.
  • the wall extending from the inner side of the cap may include at least one detent
  • the sieve includes the perforated top
  • the wall extending from the perforated top and may include at least one detent extending from the wall
  • mounting the sieve to the cap may include forming an interference fit between the detents and the opposite walls.
  • One or more of the container, the hinge, the cap, and the sieve may be formed by injection molding.
  • the hinge may be formed integrally with the container and the cap.
  • the hinge may not be formed integrally with one or both of the container and the cap.
  • Fig. la is a side view of one embodiment of a package having a flip top lid in an opened position.
  • Fig. lb is a top view of the package of Fig. la.
  • Fig. 2 is a top plan view of another embodiment of a package having a flip top lid in a closed position.
  • Fig. 3 is a cross-sectional side view of the package of Fig. 2 in a closed position.
  • Fig. 4 is an enlarged sectional view of the hinge connecting the container with the cap and locking of the cap onto the body of the container in a closed position.
  • Fig. 5 is a top plan view of the package of Fig. 2 in an opened position.
  • Figs. 6a and 6b are sectional side views and top plan views, respectively of the plastic sieve that retains the desiccant within the compartment of the cap.
  • Fig. 7 is a longitudinal sectional view of the package of Fig. 2 in an opened position.
  • the inventors have generally developed a package for containing materials that require a substantially moisture-free or reduced moisture environment.
  • the package includes a container, a flip-top cap, a hinge joining the cap to the container, and a sieve.
  • the container may be a bottle, cylinder, or other article that functions to hold, for example, pharmaceutical dosage forms.
  • the flip-top cap has an inner side, an outer side, and a wall extending from the inner side. The inner side and the wall define a compartment.
  • the hinge joins the container and the cap.
  • the sieve is configured to be mounted to the wall extending from the inner side to retain a desiccant material in the compartment.
  • a package 10 include a container 1 which may be of a cylindrical type having a closed bottom with a lid or cap 2 integrally formed with the body of the container. As illustrated in Figs, la and lb, the container 1 and the lid or cap 2 are affixed together or attached to each other by a hinge 3. Although hinge 3 is shown as being integrally formed with the container 1 and cap 2, the hinge 3 can be formed such that it can be mounted to the container in a manner that makes the cap difficult to lose.
  • the container can have an outer circumferential groove that receives a ring that is integral with the cap. Because the ring is received in the groove, it will be difficult to remove from the container thereby keeping the opened cap with the container.
  • the lid or cap 2 has a built in compartment 4 for housing a desiccant on its inner side 7.
  • a suitable desiccant material is enclosed within the compartment 4 with the help of a plastic sieve 5 (sieve openings not shown in Fig. lb) which is snap-fitted on the circumferential lip(s) or wall 9 that extends from the inner side 7 of the desiccant compartment.
  • the compartment 4 is defined at least in part by the lip or wall 9 and the inner side 7.
  • the lip or wall 9 may have multiple configurations (e.g., curved, straight edged, a step shape, interrupted, etc.) so long as the lip functions to retain the compartment 4 to the cap 2.
  • the compartment may be retained by an interference fit, a threaded means, etc. as are known to those of ordinary skill in the art.
  • the cap 2 has an outer side 8 and an extended portion 6, which acts as a lever in opening the cap.
  • a second embodiment of a package 100 includes a container 101, a lid or cap 102, and a hinge 103 that joins the lid to the container.
  • the lid 102 includes a compartment 104 that receives a desiccant material, a sieve cap 105 mounted to a circumferential lip or wall 109 to retain the desiccant material within the compartment 104, and an extended portion 106 which acts as a lever in opening the lid.
  • the lid 102 also has an inner side 107 and an outer side 108. The inner side 107 is adjacent to the desiccant.
  • the compartment 104, which receives the desiccant is defined by the circumferential lip or wall 109 and the inner side 107.
  • the wall 109 includes an inner surface 115 and an outer surface 116.
  • the lid also includes an optional circumferential channel 110 having an outer edge 112 that mates with a circumferential lip 114 of the container 101.
  • the channel 110 can be replaced by, for example, merely extending the outer surface 116 of the cap such that it contacts the lip 114 and forms a seal.
  • the seal formed between the lip 114 and the outer edge 112 serves as a barrier to moisture entry.
  • the container 101 also includes a circumferential lip 118 that extends outwardly from the container and serves as a stop to the lip 102 when the lid is closed against the container.
  • the sieve 105 mates with the circumferential lip 109 of the compartment 104 using any means that ensure that the sieve is retained against the circumferential lip and compartment.
  • Fig. 4 illustrates the use of a pair of detents 120 and 122 that extend inwardly from the sieve 105 and outwardly from the compartment 104, respectively.
  • detent 122 extends from the outer surface 116 of the wall 109.
  • the sieve will be securely retained against the lip 109, thereby keeping the desiccant within the lid.
  • the sieve can be configured to fit within the compartment 104 against the inner surface 115. The detents then would extend inwardly from the wall 109 and outwardly from the sieve.
  • the sieve 105 includes a perforated plate 123 from which the circumferential wall 124 extends. When the sieve 105 is mounted to the compartment 104, the circumferential wall 124 generally overlaps the lip or wall 109, thereby providing additional protection from moisture.
  • the container body is constructed from a substantially moisture impermeable, polyolefin material. While it is contemplated that any polyolefin may be utilized, polypropylene is particularly useful for the construction of the container and cap. Polypropylene is desirable because of its durability, rigidity, flexural resistance and impact resistance after being molded into the form of a container. Particularly, the container and cap are manufactured by injection molding suitable combination of polyolefins and elastomers. Suitable polyolefins include one or more of polyethylene and polypropylene.
  • Suitable elastomers include one or more of polyisoprene, polybutadiene, polyisobutylene, polyurethanes and copolymers, such as poly (styrene-butadiene styrene), ethylene methacrylate copolymer and ethylene vinyl acetate copolymer.
  • Suitable desiccant materials include one or more of montmorillonite clay, silica gel, molecular sieve, calcium oxide, calcium sulphate and calcium chloride.
  • the choice of desiccant material is not critical to the invention. The amount of desiccant is determined by the needs of the user.
  • the sieve on the desiccant compartment may be constructed using any thermoplastic. Particularly, it can be prepared from high density polyethylene (HDPE).
  • HDPE high density polyethylene
  • HDPE is a high density version of polyethylene. It is harder, stronger and has better chemical resistance than low density polyethylene.
  • the container and cap may be manufactured by, for example, the process of injection molding. In this process, plastic parts are molded by using heat and pressure during the injection of a molten plastic polymer into a desired mold.
  • the package is designed with a differential wall thickness across the cross-section of the container body which enables it to achieve the requisite air-tightness while keeping the pack easy to open. It is a desirable option to design the package to be a secure package.
  • a secure pack is one that has an indicator or barrier to entry, which, if breached or missing can reasonably be expected to provide visible evidence to the consumer that tampering has occurred. While nonetheless desirable, this type of packaging is an option and the inventions described herein can be applied to products that do not have a tamper-evident packaging.
  • Tamper-evident packaging can be provided using heat shrink wrappers, film wrappers, sealed tubes, etc.
  • Shrink sleeving is the most widely used due to its ease of use. It involves simply placing the shrink sleeve over the component and applying heat. The sleeve shrinks and encapsulates the component. It also provides good insulation, chemical resistance, toughness and excellent colourability.
  • the shrink sleeves may be prepared from one or more of polyethylene, polypropylene, polyvinylchloride, polystyrene or polyester.
  • Air-tightness in the pack is ascertained by vacuum-leakage test method using a desiccator fitted with a vacuum pump. The packs are tested at 15 inch of mercury pressure for 2 minutes. Packs in which no water enters is termed air-tight.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)

Abstract

La présente invention concerne un emballage constitué d'un contenant et d'un couvercle à dessus rabattable pourvu d'un élément intégré destiné à un siccatif. L'invention concerne notamment des emballages destinés à des substances sensibles à l'humidité, en particulier des préparations pharmaceutiques. Cet emballage est constitué d'un contenant (101), d'un couvercle à dessus rabattable (102), d'une charnière (103) unissant le contenant et le couvercle, et d'un tamis (105). Ce couvercle à dessus rabattable présente une face intérieure (107), une face extérieure (108), et une paroi (109) s'étendant depuis ladite face intérieure. La face intérieure et la paroi définissent un compartiment (104). Le tamis comporte une partie supérieure ajourée (123) et une paroi (124) s'étendant depuis cette dernière, le tamis étant configuré de manière à se fixer sur la paroi (109) en vue de maintenir au moins une substance siccative dans le compartiment.
PCT/IB2004/001335 2003-04-30 2004-04-30 Contenant a dessus de couvercle rabattable a siccatif integre WO2004096658A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04730611A EP1638856A1 (fr) 2003-04-30 2004-04-30 Contenant a dessus de couvercle rabattable a siccatif integre

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN648/DEL/2003 2003-04-30
IN648DE2003 2003-04-30

Publications (1)

Publication Number Publication Date
WO2004096658A1 true WO2004096658A1 (fr) 2004-11-11

Family

ID=33397658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/001335 WO2004096658A1 (fr) 2003-04-30 2004-04-30 Contenant a dessus de couvercle rabattable a siccatif integre

Country Status (2)

Country Link
EP (1) EP1638856A1 (fr)
WO (1) WO2004096658A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012131A2 (fr) * 2003-07-29 2005-02-10 AIRSEC S.A. (Société Anonyme) Conteneur dessicatif etanche pour le conditionnement de produits sensibles a l’humidite ambiante
WO2007034093A1 (fr) * 2005-09-23 2007-03-29 AIRSEC (Société par Actions Simplifiée) Conteneur monobloc a capot/couvercle a charniere
US8360257B2 (en) 2008-10-24 2013-01-29 Airsec S.A.S. Screw cap, container body and container
US8365932B2 (en) 2003-12-19 2013-02-05 Airsec S.A. Device for the leak-tight sealing of packaging containers for sensitive products
US8783485B2 (en) 2007-11-16 2014-07-22 Clariant Production (France) S.A.S. Container
DE102014106507A1 (de) 2014-05-08 2015-11-12 Sanner Gmbh Behälter und Verfahren zu dessen Herstellung

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LT3038670T (lt) 2013-08-30 2020-11-25 Hollister Incorporated Prietaisas trans analinei irigacijai
EP3148625B1 (fr) 2014-05-30 2023-07-05 Hollister Incorporated Emballage de cathéter à ouverture par soulèvement
EP3166661B1 (fr) 2014-07-08 2019-01-09 Hollister Incorporated Dispositif d'irrigation trans-anale portable
EP3166662B1 (fr) 2014-07-08 2023-06-07 Hollister Incorporated Plateforme d'irrigation transanale ayant un module de lit
US11103676B2 (en) 2016-04-22 2021-08-31 Hollister Incorporated Medical device package with flip cap having a snap fit
EP3445435A1 (fr) 2016-04-22 2019-02-27 Hollister Incorporated Emballage de dispositif médical doté d'une capsule à vis
EP3593831B1 (fr) 2016-07-08 2023-09-06 Hollister Incorporated Reservoir d'alimentation en liquide pour dispositif d'irrigation de cavité corporelle
EP3554580B1 (fr) 2016-12-14 2020-10-07 Hollister Incorporated Dispositif et système d'irrigation transanale
WO2018156589A2 (fr) 2017-02-21 2018-08-30 Hollister Incorporated Emballage de dispositif médical à couvercle rabattable à encliquetage
EP3700612B1 (fr) 2017-10-25 2024-06-19 Hollister Incorporated Capuchons pour emballages de cathéters
CA3084803C (fr) 2017-12-08 2024-06-11 Hollister Incorporated Produit de catheter et emballage comprenant un moyen hygienique de retrait de l'emballage

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB731417A (en) * 1952-12-17 1955-06-08 Aviso Aksjeselskap Improvements in or relating to closures for bottles, vials and the like
FR2260512A1 (en) * 1974-02-12 1975-09-05 Sanner Kg Friedr Stopper with dessication insert - has distance piece on insert capsule wall clear of stopper boss when released
EP0147507A2 (fr) * 1983-12-24 1985-07-10 Friedrich Sanner GmbH & Co. KG Spritzgusswerk Fermeture inviolable
US5992659A (en) * 1997-09-25 1999-11-30 Pano Cap (Canada) Limited Tamper proof flip top cap
JP2003063551A (ja) * 2001-08-21 2003-03-05 Sato Kasei Kogyosho:Kk 容 器

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB731417A (en) * 1952-12-17 1955-06-08 Aviso Aksjeselskap Improvements in or relating to closures for bottles, vials and the like
FR2260512A1 (en) * 1974-02-12 1975-09-05 Sanner Kg Friedr Stopper with dessication insert - has distance piece on insert capsule wall clear of stopper boss when released
EP0147507A2 (fr) * 1983-12-24 1985-07-10 Friedrich Sanner GmbH & Co. KG Spritzgusswerk Fermeture inviolable
US5992659A (en) * 1997-09-25 1999-11-30 Pano Cap (Canada) Limited Tamper proof flip top cap
JP2003063551A (ja) * 2001-08-21 2003-03-05 Sato Kasei Kogyosho:Kk 容 器

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 2003, no. 07 3 July 2003 (2003-07-03) *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005012131A2 (fr) * 2003-07-29 2005-02-10 AIRSEC S.A. (Société Anonyme) Conteneur dessicatif etanche pour le conditionnement de produits sensibles a l’humidite ambiante
WO2005012131A3 (fr) * 2003-07-29 2005-03-31 Airsec S A Sa Conteneur dessicatif etanche pour le conditionnement de produits sensibles a l’humidite ambiante
US8365932B2 (en) 2003-12-19 2013-02-05 Airsec S.A. Device for the leak-tight sealing of packaging containers for sensitive products
WO2007034093A1 (fr) * 2005-09-23 2007-03-29 AIRSEC (Société par Actions Simplifiée) Conteneur monobloc a capot/couvercle a charniere
US8783485B2 (en) 2007-11-16 2014-07-22 Clariant Production (France) S.A.S. Container
US8360257B2 (en) 2008-10-24 2013-01-29 Airsec S.A.S. Screw cap, container body and container
DE102014106507A1 (de) 2014-05-08 2015-11-12 Sanner Gmbh Behälter und Verfahren zu dessen Herstellung
WO2015169651A1 (fr) * 2014-05-08 2015-11-12 Sanner Gmbh Récipient et procédé de fabrication de celui-ci

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