COMPOSITION FOR INHIBITING THE GROWTH OF UNWANTED HAIR
This invention relates to a composition for inhibiting the growth of unwanted hair on human skin. Specifically, it discloses a novel composition for safely and effectively inhibiting the growth of unwanted hair without affecting the hormonal balance in the body thereby significantly reducing the possible side effects.
BACKGROUND OF THE INVENTION
Humans desire hair to grow in certain areas of the body and in other areas of the body, humans do not wish hair to grow. Much effort has been given to various methods to remove unwanted hair and to prevent its regrowth. These include mechanical methods, chemical methods and systemic methods.
Mechanical methods have included shaving, physical removal of the hair by using tweezers and plucking the hair away, and application of hot wax strips which pull the hair away from the body. These and other methods are of limited value since they remove hair in a small confined area and are quite painful, lead to skin irritation and do nothing to permanently stop hair regrowth.
Chemical methods include the use of depilatory compositions which generally cause the hair fibre to disintegrate. Many cause dermal irritation and cannot be used on sensitive areas of the skin.
Systemic methods include the ingestion of hormones which are thought to be able to control the hormonal balance in the body which affect hair growth. Each of these methods have
advantages and disadvantages but none have proven effective in permanently removing unwanted hair and preventing hair regrowth.
It is therefore an object of the present invention to provide a safe and effective topical composition which effectively inhibits the growth of unwanted hair.
It is a further object of this invention to provide a safe and effective topical composition which prevents regrowth of unwanted and which does not irritate the skin.
It is a yet further object of the present invention to provide a safe and effective topical composition which effectively prevents the regrowth of unwanted hair which can be incorporated into a variety of vehicles for easy application.
SUMMARY OF THIS INVENTION
To this end, in one of its aspects, the invention provides a topical composition which inhibits the regrowth of hair and which comprises the sodium salt of uric acid and glycerol.
In yet another of its aspects, the invention provides a topical composition which inhibits the regrowth of hair and which comprises the sodium salt of trihydroxypurine and glycerol as the solvent.
In a further object of this invention is provided a topical composition which inhibits the regrowth of hair and which comprises the sodium salt of uric acid and glycerol wherein the amount of the sodium salt of uric acid is present from trace amounts to 3.5 percent by volume.
In yet another aspect, the invention provides a method for preventing regrowth of unwanted hair in a mammal which comprises applying topically to an area of the skin, a composition which comprises the sodium salt of uric acid and glycerol.
DETAILED DESCRIPTION OF THE INVENTION
The inventor has found that fungi are present around the hair root or hair bulb in an area of the skin which suffers from hair loss. The fungi, both members of the Actinomyces family, secrete a waste product which will, when accumulating in a significantly large amount, cause the hair bulb to shrivel up and die which in turn causes the hair shaft to fall out. Once the hair bulb is killed, the blood supply will stop in about to six to eight months thereby causing permanent hair loss in that area in which the blood supply has stopped. Hair will not regrow in that area. This is commonly referred to as the Mailman Syndrome. Much work has been done on trying to restart the blood flow in those areas but so far, such efforts have been unsuccessful.
The inventor has found that if the properties of the waste products secreted by the fungi can be duplicated and apphed to healthy hair follicles, that will cause the hair bulb to die and the blood flow to the area to be stopped thereby resulting in permanent hair loss.
In doing so, the inventor has found that permanent hair loss can be created without affecting the hormonal balance in the body. The level of dihydrotestosterone which is the hormone which feeds the fungi is not affected at all, thereby eliminating the side effects of systemic products which affect hormonal balance in the body.
If the amount of dihydrotestosterone is increased, the amount of the fungi present will increase thereby increasing the amount of waste product thereby decreasing the amount of hair present. If the amount of dihydrotestosterone is decreased, less fungi is produced which produces less waste product which improves the quality of the hair.
The present invention will duplicate the effect of the waste product of the fungi without altering the level of dihydrotestosterone in the body. This is a significant advance since the invention will cause the same results without the undesired side effects.
The inventor has found that the use of the sodium salt of uric acid (sodium salt of trihydroxypurine - CsH N403Na) in a glycerol base when applied topically to hair on the skin, will duplicate the effect of the waste product of the fungi thereby causing permanent hair loss. The amount of the sodium salt of the uric acid may be from a trace amount to 3.5 percent and glycerol is used as the solvent.
EXAMPLES
The inventors have found that the composition may be incorporated into various formulations. These include lotions, creams, sprays, deodorants and gels. The composition may be incorporated into both aerosol sprays or in non-aerosol sprays as an appropriate vehicle. The composition of the present invention is illustrated in the following non-limiting examples. All parts, percentages and ratios used herein are by volume unless stated otherwise. Conventional methods are used to produce the final product. For ease of reference, the Master Mix referred to in the following formulations is expressed as follows:
MASTER MIX:
60% vegetable glycerine
37% de-ionized water
3% sodium salt of uric acid (2, 6, 8-Trihydroxypurine) (C5H3N403Na)
Example 1 - LOTION: 11,600 It. Mineral Oil
3,800 Sepigel 502
1,950 Master Mix
82,650 De-ionized Water q.s. Fragrance
Example 2 - LOTION: 1,200 Cremophor A-6
1,200 Cremophor A-25
2,000 GMS-SE
1,600 Cetyl Alcohol
3,200 It. Mineral Oil
0,800 IPM
0,800 IPP
2,000 Eutanol G
84,195 De-ionized Water
0,070 Carbopol
1,600 Master Mix
1,000 Germaben II
0,200 Fragrance
0,135 Triethanolamine
Example 3 - CREAM: 1,250 Cremophor A-6
1,250 Cremophor A-25
1,600 Stearyl Alcohol
1,770 Promulgen G
1,050 It. Mineral Oil
0.070 Carbopol
2,400 Glycerine
2,000 Master Mix
0.135 Triethanolamine
0.200 Fragrance
88.275 De-ionized Water
Example 4 - CREAM: 11,600 It. Mineral Oil
4,000 Sepigel 305
1,950 Master Mix
82,450 De-ionized Water q.s. Fragrance
Example 5 - SPRAY: 93,000 De-ionized Water
0.300 Fragrance
2,000 Master Mix
4,700 Methanol
Example 6 - DEODORANT STICK:
48,800 Propylene Glycol
26,000 De-ionized Water
2,000 Master Mix
8,000 Sodium Stearate
0,100 Triclosan
3,000 Arosurf
10,000 Steareth-100
1,000 Triethanolamine
0,200 Fragrance
Example 7 - DEODORANT STICK:
45,000 Propylene Glycol
40,000 De-ionized Water
1,000 Sodium Hydroxide
5,000 Stearic Acid
6,500 Methanol
0.200 Triclosan
2,000 Master Mix
0.300 Fragrance
Example 8 - DEODORANT STICK:
64,000 Propylene Glycol
22,000 De-ionized Water
5,000 DEA
7,000 Sodium Stearate
2,000 Master Mix q.s. Fragrance
Example 9 - DEODORANT SPRAY:
93,200 De-ionized Water
2,000 Master Mix
4,200 Methanol
0,200 Triclosan
0.400 Fragrance
Example 10 - GEL: 96,000 De-ionized Water
0,150 Carbopol
0,950 Aloe Vera Gel 10X
1,600 Master Mix
0,300 Triethanolamine
1,000 Polysorbate-20 q.s. Fragrance
The Master Mix may also be incorporated in a wet towelette and applied to the skin by wiping the towelette over the desired area.
While particular embodiments of the subject invention have been described, it will be obvious to one skilled in the art that various changes and modifications of the subject invention can be made without departing from the spirit and scope of the invention.