WO2004033655A2 - Transporteur de solute organique humain - Google Patents

Transporteur de solute organique humain Download PDF

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Publication number
WO2004033655A2
WO2004033655A2 PCT/US2003/032087 US0332087W WO2004033655A2 WO 2004033655 A2 WO2004033655 A2 WO 2004033655A2 US 0332087 W US0332087 W US 0332087W WO 2004033655 A2 WO2004033655 A2 WO 2004033655A2
Authority
WO
WIPO (PCT)
Prior art keywords
conjugate
transporter
agent
sequence
nucleic acid
Prior art date
Application number
PCT/US2003/032087
Other languages
English (en)
Other versions
WO2004033655A3 (fr
Inventor
Noa Zerangue
Christopher Paddon
Original Assignee
Xenoport, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenoport, Inc. filed Critical Xenoport, Inc.
Priority to AU2003279917A priority Critical patent/AU2003279917A1/en
Priority to US10/763,644 priority patent/US20040161424A1/en
Publication of WO2004033655A2 publication Critical patent/WO2004033655A2/fr
Publication of WO2004033655A3 publication Critical patent/WO2004033655A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Abstract

L'invention concerne plusieurs protéines transporteuses, des acides nucléiques codant pour celles-ci et des procédés utilisant les transporteurs à des agents de criblage, des conjugués ou des fractions de conjugués, liés ou pouvant être liés à des agents, en vue d'avoir la capacité d'être transportés en tant que substrats par les transporteurs. L'invention concerne également des procédés de traitement impliquant l'administration orale d'agents qui, soit seuls, soit à la suite de liaison à une fraction conjuguée, sont des substrats de l'un des transporteurs.
PCT/US2003/032087 2002-10-08 2003-10-08 Transporteur de solute organique humain WO2004033655A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003279917A AU2003279917A1 (en) 2002-10-08 2003-10-08 Human organic solute transporters
US10/763,644 US20040161424A1 (en) 2002-10-08 2004-01-22 Human organic solute transporters

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41729802P 2002-10-08 2002-10-08
US60/417,298 2002-10-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/763,644 Continuation-In-Part US20040161424A1 (en) 2002-10-08 2004-01-22 Human organic solute transporters

Publications (2)

Publication Number Publication Date
WO2004033655A2 true WO2004033655A2 (fr) 2004-04-22
WO2004033655A3 WO2004033655A3 (fr) 2005-06-23

Family

ID=32093997

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/032087 WO2004033655A2 (fr) 2002-10-08 2003-10-08 Transporteur de solute organique humain

Country Status (2)

Country Link
AU (1) AU2003279917A1 (fr)
WO (1) WO2004033655A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075992A1 (fr) * 2004-01-30 2005-08-18 Xenoport, Inc. Transporteur mct1 exprime dans des cellules de la barriere hemato-encephalique
WO2006001986A2 (fr) * 2004-06-04 2006-01-05 Xenoport, Inc. Transporteurs glut3 exprimes dans des cellules cancereuses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061471A2 (fr) * 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Proteines transmembranaires humaines
WO2001049728A2 (fr) * 2000-01-06 2001-07-12 Protegene Inc. Proteines humaines a domaines hydrophobes et adn codant ces proteines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061471A2 (fr) * 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Proteines transmembranaires humaines
WO2001049728A2 (fr) * 2000-01-06 2001-07-12 Protegene Inc. Proteines humaines a domaines hydrophobes et adn codant ces proteines

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075992A1 (fr) * 2004-01-30 2005-08-18 Xenoport, Inc. Transporteur mct1 exprime dans des cellules de la barriere hemato-encephalique
US7452680B2 (en) 2004-01-30 2008-11-18 Xenoport, Inc. MCT1 transporters expressed in blood brain barrier cells
WO2006001986A2 (fr) * 2004-06-04 2006-01-05 Xenoport, Inc. Transporteurs glut3 exprimes dans des cellules cancereuses
WO2006001986A3 (fr) * 2004-06-04 2006-08-03 Xenoport Inc Transporteurs glut3 exprimes dans des cellules cancereuses

Also Published As

Publication number Publication date
WO2004033655A3 (fr) 2005-06-23
AU2003279917A8 (en) 2004-05-04
AU2003279917A1 (en) 2004-05-04

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