WO2004033655A3 - Transporteur de solute organique humain - Google Patents

Transporteur de solute organique humain Download PDF

Info

Publication number
WO2004033655A3
WO2004033655A3 PCT/US2003/032087 US0332087W WO2004033655A3 WO 2004033655 A3 WO2004033655 A3 WO 2004033655A3 US 0332087 W US0332087 W US 0332087W WO 2004033655 A3 WO2004033655 A3 WO 2004033655A3
Authority
WO
WIPO (PCT)
Prior art keywords
transporters
agents
organic solute
substrates
human organic
Prior art date
Application number
PCT/US2003/032087
Other languages
English (en)
Other versions
WO2004033655A2 (fr
Inventor
Noa Zerangue
Christopher Paddon
Original Assignee
Xenoport Inc
Noa Zerangue
Christopher Paddon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenoport Inc, Noa Zerangue, Christopher Paddon filed Critical Xenoport Inc
Priority to AU2003279917A priority Critical patent/AU2003279917A1/en
Priority to US10/763,644 priority patent/US20040161424A1/en
Publication of WO2004033655A2 publication Critical patent/WO2004033655A2/fr
Publication of WO2004033655A3 publication Critical patent/WO2004033655A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne plusieurs protéines transporteuses, des acides nucléiques codant pour celles-ci et des procédés utilisant les transporteurs à des agents de criblage, des conjugués ou des fractions de conjugués, liés ou pouvant être liés à des agents, en vue d'avoir la capacité d'être transportés en tant que substrats par les transporteurs. L'invention concerne également des procédés de traitement impliquant l'administration orale d'agents qui, soit seuls, soit à la suite de liaison à une fraction conjuguée, sont des substrats de l'un des transporteurs.
PCT/US2003/032087 2002-10-08 2003-10-08 Transporteur de solute organique humain WO2004033655A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003279917A AU2003279917A1 (en) 2002-10-08 2003-10-08 Human organic solute transporters
US10/763,644 US20040161424A1 (en) 2002-10-08 2004-01-22 Human organic solute transporters

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41729802P 2002-10-08 2002-10-08
US60/417,298 2002-10-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/763,644 Continuation-In-Part US20040161424A1 (en) 2002-10-08 2004-01-22 Human organic solute transporters

Publications (2)

Publication Number Publication Date
WO2004033655A2 WO2004033655A2 (fr) 2004-04-22
WO2004033655A3 true WO2004033655A3 (fr) 2005-06-23

Family

ID=32093997

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/032087 WO2004033655A2 (fr) 2002-10-08 2003-10-08 Transporteur de solute organique humain

Country Status (2)

Country Link
AU (1) AU2003279917A1 (fr)
WO (1) WO2004033655A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005075992A1 (fr) * 2004-01-30 2005-08-18 Xenoport, Inc. Transporteur mct1 exprime dans des cellules de la barriere hemato-encephalique
WO2006001986A2 (fr) * 2004-06-04 2006-01-05 Xenoport, Inc. Transporteurs glut3 exprimes dans des cellules cancereuses

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061471A2 (fr) * 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Proteines transmembranaires humaines
WO2001049728A2 (fr) * 2000-01-06 2001-07-12 Protegene Inc. Proteines humaines a domaines hydrophobes et adn codant ces proteines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061471A2 (fr) * 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Proteines transmembranaires humaines
WO2001049728A2 (fr) * 2000-01-06 2001-07-12 Protegene Inc. Proteines humaines a domaines hydrophobes et adn codant ces proteines

Also Published As

Publication number Publication date
AU2003279917A8 (en) 2004-05-04
AU2003279917A1 (en) 2004-05-04
WO2004033655A2 (fr) 2004-04-22

Similar Documents

Publication Publication Date Title
WO2006040129A3 (fr) Conjugues de proteine utilisables en therapie, pour le diagnostic et en chromatographie
WO2008073162A3 (fr) Sites d'acétylation de lysine
WO2007047834A3 (fr) Conjugués de peptides pour administration par voie orale pour traiter des maladies métaboliques
WO2006050930A3 (fr) Composes a molecules conjugues presentant une activite d'absorption de cellules ameliorees
WO2004005326A3 (fr) Conjugues de tubulysine
WO2000056774A8 (fr) Procede d'utilisation de bioelastomeres
WO2006116475A3 (fr) Compositions immunostimulantes
WO2002002638A3 (fr) Methodes de traitement de maladies rhumatismales a l'aide d'une molecule ctla4 soluble
WO2006047631A3 (fr) Composes antimitotiques antiproliferatifs
EP2230254A3 (fr) Combinaisons thérapeutiques d'anticorps anti-igfr1
IL157993A0 (en) Molecular conjugates for use in cancer treatment and methods for the preparation thereof
WO2002083171A3 (fr) Traitement du cancer par utilisation d'anticorps specifiques de la fap-alpha
AU2002364954A1 (en) ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO BLyS
HUP0402626A3 (en) Photochemical internalization for virus-mediated molecule delivery into the cyosol
WO2001092283A3 (fr) Composes de cobalamine utilises en tant qu'agents cardio-vasculaires et agents d'imagerie
WO2008054597A3 (fr) Sites de phosphorylation de tyrosine
WO2008013954A3 (fr) Sites de phosphorylation de la tyrosine
NL1024831A1 (nl) N-terminaal monogepegyleerde conjugaten van humaan groeihormoon en werkwijze voor de bereiding daarvan.
AP2001002377A0 (en) Substituted phenoxyacetic acids.
WO2008013934A3 (fr) Sites de phosphorylation de tyrosines
EP1153607A3 (fr) Hormone de croissance pour le traitement de l'inflammation articulaire
WO2005042566A3 (fr) Peptides pour traitement et prevention de l'endometriose
AU2002309122A1 (en) Compositions based on branched chain amino acids for improving the myocardial ventricular function in patients suffering from diabetes
WO2008021542A3 (fr) Sites d'acétylation de la lysine
WO2004033655A3 (fr) Transporteur de solute organique humain

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 10763644

Country of ref document: US

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP