WO2004015427A3 - Methodes diagnostiques et therapeutiques s'adressant a des maladies associees au recepteur 19 couple a la proteine g (gpr19) - Google Patents

Methodes diagnostiques et therapeutiques s'adressant a des maladies associees au recepteur 19 couple a la proteine g (gpr19) Download PDF

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Publication number
WO2004015427A3
WO2004015427A3 PCT/EP2003/008142 EP0308142W WO2004015427A3 WO 2004015427 A3 WO2004015427 A3 WO 2004015427A3 EP 0308142 W EP0308142 W EP 0308142W WO 2004015427 A3 WO2004015427 A3 WO 2004015427A3
Authority
WO
WIPO (PCT)
Prior art keywords
gpr19
therapeutics
diagnostics
diseases associated
coupled receptor
Prior art date
Application number
PCT/EP2003/008142
Other languages
English (en)
Other versions
WO2004015427A2 (fr
Inventor
Stefan Golz
Ulf Brueggemeier
Holger Summer
Original Assignee
Bayer Healthcare Ag
Stefan Golz
Ulf Brueggemeier
Holger Summer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Stefan Golz, Ulf Brueggemeier, Holger Summer filed Critical Bayer Healthcare Ag
Priority to AU2003250165A priority Critical patent/AU2003250165A1/en
Publication of WO2004015427A2 publication Critical patent/WO2004015427A2/fr
Publication of WO2004015427A3 publication Critical patent/WO2004015427A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un GPR19 humain associé aux maladies hématologiques, cancer, maladies cardio-vasculaires et troubles du système périphérique et central. Elle concerne également des méthodes servant à identifier les composés utiles pour traiter ou prévenir des maladies hématologiques, le cancer, des maladies cardio-vasculaires et des troubles du système nerveux périphérique et central. Elle concerne également des composés se fixant à GPR19 et/ou activant ou inhibant l'activité de ce dernier, ainsi que des compositions pharmaceutiques contenant ces composés.
PCT/EP2003/008142 2002-08-06 2003-07-24 Methodes diagnostiques et therapeutiques s'adressant a des maladies associees au recepteur 19 couple a la proteine g (gpr19) WO2004015427A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003250165A AU2003250165A1 (en) 2002-08-06 2003-07-24 Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 19 (gpr19)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02017627.7 2002-08-06
EP02017627 2002-08-06

Publications (2)

Publication Number Publication Date
WO2004015427A2 WO2004015427A2 (fr) 2004-02-19
WO2004015427A3 true WO2004015427A3 (fr) 2005-06-09

Family

ID=31502693

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/008142 WO2004015427A2 (fr) 2002-08-06 2003-07-24 Methodes diagnostiques et therapeutiques s'adressant a des maladies associees au recepteur 19 couple a la proteine g (gpr19)

Country Status (2)

Country Link
AU (1) AU2003250165A1 (fr)
WO (1) WO2004015427A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021088920A1 (fr) * 2019-11-05 2021-05-14 上海翰森生物医药科技有限公司 Régulateur de dérivé de benzothiophène, son procédé de préparation et son utilisation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022129A1 (fr) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Recepteurs couples a la proteine g humaine non endogenes et actives de façon constitutive
WO2001044295A2 (fr) * 1999-12-17 2001-06-21 Astrazeneca Ab Nouveau compose
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
WO2003000928A2 (fr) * 2001-06-25 2003-01-03 Buadbo Aps Innovation en matiere de therapie anti-cancereuse

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022129A1 (fr) * 1998-10-13 2000-04-20 Arena Pharmaceuticals, Inc. Recepteurs couples a la proteine g humaine non endogenes et actives de façon constitutive
WO2001044295A2 (fr) * 1999-12-17 2001-06-21 Astrazeneca Ab Nouveau compose
WO2002061087A2 (fr) * 2000-12-19 2002-08-08 Lifespan Biosciences, Inc. Peptides antigeniques destines a des recepteurs couples a la proteine g (gpcr), anticorps s'y rapportant, et systeme d'identification desdits peptides antigeniques
WO2003000928A2 (fr) * 2001-06-25 2003-01-03 Buadbo Aps Innovation en matiere de therapie anti-cancereuse

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISS-PROT [online] 1 November 1997 (1997-11-01), XP002262914, Database accession no. Q15760 *
O'DOWD B F ET AL: "A NOVEL GENE CODES FOR PUTATIVE G PROTEIN-COUPLED RECEPTOR WITH AN ABUNDANT EXPRESSION IN BRAIN", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 394, no. 3, 7 October 1996 (1996-10-07), pages 325 - 329, XP000984803, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO2004015427A2 (fr) 2004-02-19
AU2003250165A1 (en) 2004-02-25

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