WO2004000398A1 - Seringue d'injection possedant une aiguille retractable - Google Patents

Seringue d'injection possedant une aiguille retractable Download PDF

Info

Publication number
WO2004000398A1
WO2004000398A1 PCT/NL2003/000229 NL0300229W WO2004000398A1 WO 2004000398 A1 WO2004000398 A1 WO 2004000398A1 NL 0300229 W NL0300229 W NL 0300229W WO 2004000398 A1 WO2004000398 A1 WO 2004000398A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle
injection
liquid holder
needle mount
outlet opening
Prior art date
Application number
PCT/NL2003/000229
Other languages
English (en)
Inventor
Bjørn Olaf GOOSSENS
Jan Hendrik Lucas
Original Assignee
Medical Patents Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL1020937A external-priority patent/NL1020937C2/nl
Application filed by Medical Patents Limited filed Critical Medical Patents Limited
Priority to AU2003225416A priority Critical patent/AU2003225416A1/en
Publication of WO2004000398A1 publication Critical patent/WO2004000398A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/322Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34Constructions for connecting the needle, e.g. to syringe nozzle or needle hub

Definitions

  • the present invention relates to an injection syringe having a retractable injection needle.
  • Injection syringes of this type are known in practice. After the liquid which is present in the liquid holder of the injection syringe has been discharged, to enable the injection needle to be retracted, by way of example the plunger head of the plunger is coupled to the needle mount of the injection needle. As a result of the plunger then being moved back again, the injection needle can be drawn into the liquid holder of the injection syringe, so that it is possible to prevent the risk of injury from the injection needle. Moreover, this ensures that the injection syringe is not reused.
  • Another drawback of the known injection syringe is that the injection needle, when the injection needle is being fitted to the outlet opening of the liquid holder, is difficult to position, i.e. in the known injection syringe the coupling means have to be positioned very accurately through the outlet opening of the liquid holder. If care is not taken during this operation, which in everyday practice is often the case, this may mean that the injection needle is not secured stably to the outlet opening of the liquid holder and/or that the coupling means will be damaged in some way, with the result that it is impossible to ensure that the injection needle will be safely retracted after the injection syringe has been used.
  • a further drawback of known injection syringes is that during coupling of the known coupling means, there is often what is known as a dead space, with the result that not all the liquid which is present in the liquid holder of the injection syringe can be discharged. This is particularly disadvantageous if an expensive liquid is used.
  • a further significant drawback is that known injection syringes are often not liquid-tight and are therefore not free of leaks. This can lead to contamination and/or degradation of liquid which is present in the liquid holder, in particular if the injection syringes still have to be stored for a certain time in the filled state. In this context, it should be noted that in many injection syringes there is no fluid-tight connection between the injection needle and the liquid holder.
  • a further object of the present invention is to provide a leak- free, liquid-tight injection syringe having a retractable injection needle which is easy to product and is also simple to use .
  • an injection syringe having a retractable injection needle at least comprising: a liquid holder having an outlet opening; a plunger, which can be displaced inside the said liquid holder and has a plunger head, to which a plunger rod is or can be secured; an injection needle with needle mount, which is or can be mounted in or on the outlet opening of the liquid holder; ' the needle mount of the injection needle and the plunger head comprising coupling means which are designed such that they can be coupled unambiguously to one another in order that, after the plunger head has been moved completely into the liquid holder in order to discharge liquid present in the liquid holder via the outlet opening, the injection needle, after the plunger head has been coupled to the needle mount of the injection needle, can be drawn into the liquid holder; the coupling means of the needle mount being designed in the form of a recess with an inwardly directed collar, and the coupling means of the plunger head being designed in the form of a projecting element with a thickened end
  • the liquid-tight, leak-free injection syringe having a retractable injection needle according to the invention is simple and inexpensive to produce on account of its simple structure and the small number of components.
  • a further advantage of the injection syringe according to the invention is that the injection needle is very easy to fit to the outlet opening of the liquid holder of the injection syringe, with the risk of damage to the coupling means of the needle mount and the piston head being substantially minimized.
  • Yet another advantage of the injection syringe according to the invention is that a coupling with "zero dead space" can be obtained, i.e. substantially all the liquid which is present in the liquid holder can also be discharged.
  • Yet another advantage of the injection syringe according to the invention is that when the injection needle is secured to the outlet opening of the liquid holder, the needle mount with injection needle can therefore only enter the liquid holder once the blocking means has been unblocked.
  • the blocking means may be designed in various ways for this purpose, provided only that it is possible to provide for unblocking after the liquid holder has been emptied.
  • the coupling mechanism according to the present invention is not limited to a "normal" injection syringe.
  • the coupling mechanism according to the present invention is also of value, for example, for use in other types of injection syringes, such as for example prefilled injection syringes, luer-lock syringes, etc., provided only that the injection needle is retracted into the liquid holder after the liquid holder has been emptied.
  • the injection needle with needle mount can be mounted in or on the outlet opening in various ways, provided that a reliable, stable and liquid-tight securing method is provided.
  • the injection needle after it has been mounted in or on the outlet opening of the liquid holder, can no longer be removed from the outlet opening, except by being pulled inward into the liquid holder after the liquid holder has been emptied.
  • FR 2 658 724 has disclosed an injection syringe having a retractable injection needle which is a very complicated design. However, FR 2 658 724 does not relate to a liquid-tight injection syringe in accordance with the present invention.
  • the term "liquid-tight" is understood as meaning that when the injection syringe has been assembled, it is impossible for any liquid to pass into or out of the injection syringe except via the injection needle.
  • the injection syringe comprises a sealing material in the outlet opening, as will be illustrated in more detail in the figures (sealing means 17 in Fig. 1) .
  • the plunger head and the needle mount of the injection needle will be coupled to one another and, at the same time, the needle mount of the injection needle will as a result be released from the outlet opening of the liquid holder.
  • the plunger head then being moved back away from the outlet opening with the aid of the plunger rod, the needle mount with injection needle is as a result drawn into the liquid holder.
  • the coupling is an "unambiguous" coupling, i.e. it is not effected by, for example, clamping or friction. This is because clamping based on friction may be insufficient for the needle mount with injection needle to be drawn back into the liquid holder after the liquid holder has been emptied.
  • the injection needle of the injection syringe according to the invention can be mounted in or on the outlet opening of the liquid holder both "through the inside” (i.e. via the end of the liquid holder which is remote from the outlet opening - cf. Fig. 1) and "around the outside” (i.e. as a result of the needle mount with injection needle being placed onto the outlet opening of the liquid holder - cf. Fig. 2) .
  • the injection needle it is preferable for it to be possible for the injection needle to be fitted "around the outside” (for example as shown in Fig. 2) .
  • the thickened end of the projecting element of the plunger head comprises an outwardly directed collar.
  • the outlet opening of the liquid holder is advantageously designed in the form of a narrowed section.
  • This narrowed section which generally forms part of the liquid holder and in this case, therefore, is fixedly connected thereto, ensures improved sealing - and therefore absence of leaks - for the injection syringe.
  • the narrowed section may, for example, be in the form of a standard cone to which standard injection needles can be fitted.
  • the narrowed section may also, for example, be provided with a screw thread or the like.
  • At least the narrowed section, and even more preferably the entire liquid holder is made from a rigid material, such as a rigid plastic, in order to improve the liquid-tightness of the injection syringe.
  • the blocking means is designed in the form of one or more resilient projections which can yield in the direction of the wall of the liquid holder when the plunger head is pressed onto the outlet opening. This ensures that, at the same time that the plunger head is coupled to the needle mount, the blocking means is also unblocked, so that it is possible to retract the needle mount together with injection needle.
  • the needle mount is provided with one or more fingers which yield inward. These yielding fingers, separately or together, form an inwardly directed collar to which the projecting element of the plunger head can be coupled. This therefore provides unambiguous coupling of the plunger head and needle mount.
  • the injection syringe advantageously comprises means for preventing rotation of the needle mount over the longitudinal axis of the liquid holder when the needle mount is mounted in or on the outlet opening of the liquid holder. This prevents the injection needle from being able to rotate in the assembled state.
  • it is possible to prevent a very painful feeling in the person receiving the injection, which is particularly the case if - as is customary in the prior art - slightly curved injection needles are being used.
  • the rotation-preventing means are formed by a protruding projection on the needle mount which can be deformed when the plunger head is coupled to the needle mount, all this in such a manner that rotation of the needle mount on the longitudinal axis of the liquid container becomes possible again (after the plunger head has been coupled to the needle mount) . It is preferable for the projection to extend over substantially the entire length of the needle mount.
  • the said means for preventing rotation of the needle mount also to form the blocking means for blocking the needle mount in the outlet opening.
  • the present invention also relates to a needle mount which is clearly intended for the injection syringe according to the invention.
  • the present invention relates to a plunger head which is clearly intended for the injection syringe according to the invention.
  • the present invention relates to a liquid holder which is clearly intended for the injection syringe according to the invention.
  • Figure 1 shows a diagrammatic cross section through an injection syringe, assembled "through the inside", with retractable injection needle in accordance with the invention
  • Figure 2 shows a diagrammatic cross section through an alternative embodiment of the injection syringe according to the invention, which is assembled "around the outside” and moreover is provided with a protective cap;
  • Figure 3 shows a diagrammatic cross section through the liquid holder of the injection syringe shown in Figure 2, on which the injection needle has not yet been mounted;
  • Figure 4 shows a perspective view of a preferred embodiment of the needle mount according to the invention
  • Figure 5 shows a diagrammatic cross section through a further alternative embodiment of the injection syringe according to the invention.
  • Figure 6 shows a partial view of the narrowed section of the liquid holder of the injection syringe shown in Fig. 5;
  • Figure 7 shows a cross section through the narrowed section in Fig. 6;
  • Figure 8 shows a diagrammatic cross section through yet another embodiment of the injection syringe according to the invention.
  • Figure 9 shows a cross section through the narrowed section in Fig. 8.
  • FIG. 1 shows a liquid-tight injection syringe 1 having a retractable injection needle 2 in accordance with the present invention.
  • the injection syringe 1 comprises a liquid holder 3 having an outlet opening 4.
  • the injection needle 2 with needle mount 8 is secured in the outlet opening 4 of the liquid holder 3.
  • the needle mount 8 of the injection needle 2 and the plunger head 6 comprise coupling means which are designed such that they can be unambiguously coupled to one another in order that, after the plunger head 6 has been moved completely into the liquid holder 3 in order to discharge liquid 9 which is present in the liquid holder 3 via the outlet opening 4, the injection needle 2, after the plunger head 6 has been coupled to the needle mount 8 of the injection needle 2, can be drawn into the liquid holder 3.
  • the term "unambiguously" coupled to one another is intended to mean that firm coupling is created, i.e. coupling which is. not based on friction or clamping.
  • the coupling means of the needle mount 8 are designed in the form of a recess 10 with an inwardly directed collar 11.
  • the coupling means of the plunger head 6 are designed in the form of a projecting element 12 with a thickened end 13.
  • the thickened end 13 of the projecting element 12 of the plunger head 6 in this case comprises an outwardly directed collar.
  • the outlet opening 4 of the liquid holder 3 comprises a narrowed section 14.
  • the narrowed section 14 forms part of the liquid holder 3 and is fixedly connected thereto, thereby contributing to improved sealing of the injection syringe 1.
  • the liquid holder 3 and narrowed section 14 are made from a rigid plastic.
  • a significant advantage in this context is that the coupling means of the needle mount 8 can be designed in such a way, as also shown in Fig. 1, that they do not extend beyond the narrowed section 14 into the liquid holder 3.
  • the outlet opening 4 of the liquid holder 3 comprises a blocking means 15 in the transition from the liquid holder 3 to the narrowed section 14.
  • This blocking means 15 is designed to block the needle mount 8 in the outlet opening 4 and can be unblocked when the plunger head 6 is coupled to the needle mount 8 of the injection needle.
  • the blocking means 15 is to this end designed in the form of a resilient projection which can yield in the direction of the wall of the liquid holder 3 when the plunger head 6 is pressed onto the outlet opening 4.
  • Fig. 1 also shows a ring 16 made from a hard material, such as metal, and a sealing means 17 with a passage.
  • the liquid holder 3 will be emptied as a result of the plunger 5 being moved towards the outlet opening 4 with the aid of the plunger rod 7.
  • the liquid 9 which is present in the liquid holder 3 is forced through the injection needle 2.
  • the blocking means 15 will be unblocked as a result of the shoulder 18 of the plunger head 6 pushing against the resilient projection.
  • a favourable aspect in this context is that during coupling of the plunger head 6 and needle mount 8 there is substantially no dead space, so that substantially all the liquid 9 which is present in the liquid holder 3 can be discharged, apart, of course, from any liquid which remains behind in the injection needle 2.
  • Figure 2 shows a diagrammatic cross section through a preferred alternative embodiment of the injection syringe 1 according to the present invention, provided with a protective cap 19.
  • the narrowed section 14 is provided with a groove 20, so that as a result the injection need 2 can be stably coupled to the liquid holder 3.
  • the injection syringe 1 can be designed in such a manner that the needle mount 8 with injection needle 2 can no longer be removed from the outlet opening 4 except by being retracted into the liquid holder 3.
  • the needle mount 8 (as shown in Fig. 2) preferably does not project beyond the outlet opening 4.
  • Figure 3 shows a diagrammatic cross section through the liquid holder 3 shown in Fig. 2, in which the injection needle 2 which is to be fitted to it has been omitted for the sake of clarity.
  • a particular aspect of the injection syringe 1 according to the invention is that it is very simple to produce, for example by injection-moulding.
  • the person skilled in the art will quickly realize that the liquid holder 3 as shown in Fig. 3 can be produced without problems .
  • the injection syringe 1 shown in Fig. 1 or Fig. 2 When the injection syringe 1 shown in Fig. 1 or Fig. 2 is in use, the injection syringe 1 will be emptied as a result of the liquid 9 which is present in the liquid holder 3 being forced through the injection needle 2 by the plunger 5 being moved towards the outlet opening 4.
  • the plunger head 6 of the plunger 5 When the injection syringe 1 is in its completely empty state, the plunger head 6 of the plunger 5 will have moved into the recess 10 in the needle mount 8. In the process, the thickened end 13 of the projecting element 12 of the plunger head 6 and the inwardly directed collar 11 of the needle mount 8 will interact and provide unambiguous coupling.
  • the blocking means 15, which is designed to block the needle mount 8 in the outlet opening 4, so that the needle mount 8 with injection needle cannot inadvertently pass into the liquid holder 3, will be unblocked as a result of, in the embodiment shown, a shoulder 18 of the plunger head 6 pushing against the resilient projection which, as a result, yields in the direction of the liquid-holder wall. If the plunger 5 is then drawn back away from the outlet opening 4 with the aid of the plunger rod 7, the needle mount 8 with injection needle 2 will as a result be drawn into the liquid holder. This prevents the injection needle 2 from being reused. Moreover, this also minimises the risk of injury from the injection needle 2.
  • FIG 4 shows a perspective view of a preferred embodiment of the needle mount according to the invention.
  • the needle mount 8 connected to the injection needle 2 comprises a recess, which is denoted overall by 10, for receiving the projecting element 12 of the plunger head 6 (cf. Fig. 1) .
  • the needle mount 8 is provided with two fingers 21 which yield inwards and of which the sides 22 which face the injection needle 2 form an inwardly directed collar 11 to which the thickened end 13 of the projecting element 12 of the plunger head 6 (cf. Fig. 1) can be unambiguously coupled.
  • the needle mount 8 preferably also comprises means 23 which prevent the needle mount 8 from rotating over the longitudinal axis of the liquid holder 3 when the needle mount 8 is mounted in or on the outlet opening 4 of the liquid holder.
  • Figures 5 and 8 each show a diagrammatic cross section through alternative embodiments of the injection syringe 1 according to the invention, the injection syringe 1 being provided with means 23 of this type for preventing the needle mount 8 from rotating over the longitudinal axis of the liquid holder 3.
  • the person skilled in the art will understand that the means 23 can be designed in a wide range of ways, provided only that the intended effect is achieved.
  • the means 23 are formed by an S-shaped blocking lip on the needle mount 8, which interacts with ribs 24 which are present in the narrowed section 14 of the liquid holder 3 and run parallel to the longitudinal axis of the liquid holder 3. This prevents the needle mount 8 from rotating over the longitudinal axis of the liquid holder 3.
  • the top part of the S-shaped blocking lip (which forms the inwardly directed collar 11) will be pressed outward, and at the same time the blocking means 15 will be unblocked, so that the needle mount 8 with injection needle can be retracted into the liquid holder 3.
  • Figure 6 shows a diagrammatic partial view of the narrowed section 14 shown in Fig. 5.
  • the inwardly projecting ribs 24 are clearly visible in this figure.
  • Figure 7 shows a plan view of a cross section through the narrowed section 14 from Fig. 6, in which the ribs 24 are shown in a different way. It will be obvious that as an alternative to the six ribs 24 shown, it is possible to use any other suitable number.
  • the rotation-preventing means 23 are designed as a protruding projection which is moved inwards when the needle mount 8 and the element 12 are coupled.
  • the means 23 functions as both a rotation-preventing means for the needle mount and as a blocking means 15 for blocking the needle mount 8 in the outlet opening 4.
  • the means 23 has three functions: 1) preventing rotation of the injection needle 2 over the longitudinal axis of the liquid holder 3; 2) blocking the needle mount 8 in the outlet opening 4 of the liquid holder 3 during injection (in this case, therefore, the means 23 carries out the function of the blocking means 15 in, for example Fig.
  • the means 23 is fulfilling the function of the inwardly directed collar 11 in, for example, Fig. 2) .
  • Figure 9 shows a plan view of a cross section through the narrowed section 14 shown in Fig. 8.
  • the means 23 will be deformed in such a manner that rotation of the needle mount 8 is no longer prevented.
  • the blocking means 15 is unblocked as a result, so that the injection needle 2 can be retracted into the liquid holder 3.

Abstract

L'invention concerne une seringue d'injection possédant une aiguille rétractable et comprenant au moins : - un réservoir de liquide pourvu d'une ouverture de sortie ; - un piston pouvant se déplacer à l'intérieur dudit réservoir et comportant une tête à laquelle une tige est fixée ou peut être fixée ; - une aiguille d'injection possédant un porte-aiguille monté ou pouvant être monté dans l'ouverture de sortie du réservoir de liquide. Le porte-aiguille et la tête de piston comportent des moyens d'accouplement conçus pour accoupler ces derniers les uns aux autres, de façon à pouvoir faire pénétrer l'aiguille d'injection dans le réservoir de liquide, après pénétration complète de la tête de piston dans ce réservoir afin d'évacuer le liquide contenu dans celui-ci par l'ouverture de sortie, après accouplement de ladite tête de piston au porte-aiguille. Les moyens d'accouplement du porte-aiguille sont conçus sous forme d'un évidement comportant un col dirigé vers l'intérieur et les moyens d'accouplement de la tête de piston sont conçus sous forme d'un élément saillant présentant une extrémité épaissie. L'ouverture de sortie du réservoir de liquide comprend des moyens de blocage conçus pour bloquer le porte-aiguille dans l'ouverture de sortie, ces moyens de blocage pouvant être débloqués quand la tête de piston est accouplée au porte-aiguille.
PCT/NL2003/000229 2002-06-25 2003-03-25 Seringue d'injection possedant une aiguille retractable WO2004000398A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003225416A AU2003225416A1 (en) 2002-06-25 2003-03-25 Injection syringe having a retractable injection needle

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL1020937 2002-06-25
NL1020937A NL1020937C2 (nl) 2002-06-25 2002-06-25 Injectiespuit met terugtrekbare inspuitnaald.
US42312802P 2002-11-01 2002-11-01
US60/423,128 2002-11-01

Publications (1)

Publication Number Publication Date
WO2004000398A1 true WO2004000398A1 (fr) 2003-12-31

Family

ID=30002428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2003/000229 WO2004000398A1 (fr) 2002-06-25 2003-03-25 Seringue d'injection possedant une aiguille retractable

Country Status (2)

Country Link
AU (1) AU2003225416A1 (fr)
WO (1) WO2004000398A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005087297A1 (fr) * 2004-03-11 2005-09-22 Meridian Medical Technologies, Inc. Ensemble aiguille et embout pour injecteur automatique
WO2006053568A1 (fr) 2004-11-22 2006-05-26 Borean Pharma Aps Antagonistes du tnf
WO2008064389A1 (fr) * 2006-11-28 2008-06-05 Morgan Meditech Inc Seringue rétractable
JP2015192925A (ja) * 2009-11-11 2015-11-05 ユニトラクト シリンジ プロプライエタリイ リミテッドUnitract Syringe Pty Ltd 格納式注射器、格納式注射器の交換式針アセンブリ、格納式注射器のバレル、格納式注射器キット、格納式注射器を操作する方法及びあらかじめ充填された注射器を製造する方法

Citations (8)

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Publication number Priority date Publication date Assignee Title
FR2658724A1 (fr) 1990-02-26 1991-08-30 Elfandi Patrice Seringue hygienique a aiguille retractable dans le corps de seringue apres usage.
US5066286A (en) * 1989-05-07 1991-11-19 Ryan Medical, Inc. Safety multiple sample luer adapter assembly
WO1993010842A1 (fr) * 1991-11-28 1993-06-10 Advanced Protective Injection Systems Medical B.V. Seringue pour injection
EP0557511A1 (fr) * 1991-09-18 1993-09-01 Jesgamabe, S.L. Seringue de securite simplifiee
US5453093A (en) * 1994-09-30 1995-09-26 Haining; Michael L. Disposable dental syringe
EP0824924A1 (fr) * 1996-08-21 1998-02-25 Long-Hsiung Chen Seringue hypodermique de sécurité
US5968020A (en) * 1993-03-12 1999-10-19 Saito; Yoshikuni Syringe assembly
GB2366205A (en) * 2000-06-06 2002-03-06 Huang Wu Shun Safety syringe with a needle sleeve

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066286A (en) * 1989-05-07 1991-11-19 Ryan Medical, Inc. Safety multiple sample luer adapter assembly
FR2658724A1 (fr) 1990-02-26 1991-08-30 Elfandi Patrice Seringue hygienique a aiguille retractable dans le corps de seringue apres usage.
EP0557511A1 (fr) * 1991-09-18 1993-09-01 Jesgamabe, S.L. Seringue de securite simplifiee
WO1993010842A1 (fr) * 1991-11-28 1993-06-10 Advanced Protective Injection Systems Medical B.V. Seringue pour injection
US5968020A (en) * 1993-03-12 1999-10-19 Saito; Yoshikuni Syringe assembly
US5453093A (en) * 1994-09-30 1995-09-26 Haining; Michael L. Disposable dental syringe
EP0824924A1 (fr) * 1996-08-21 1998-02-25 Long-Hsiung Chen Seringue hypodermique de sécurité
GB2366205A (en) * 2000-06-06 2002-03-06 Huang Wu Shun Safety syringe with a needle sleeve

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7544189B2 (en) 2000-10-10 2009-06-09 Meridian Medical Technologies, Inc. Needle and hub assembly for automatic injector
US7757370B2 (en) 2000-10-10 2010-07-20 Meridian Medical Technologies, Inc. Methods of forming a needle and hub assembly for automatic injectors
WO2005087297A1 (fr) * 2004-03-11 2005-09-22 Meridian Medical Technologies, Inc. Ensemble aiguille et embout pour injecteur automatique
JP2007528281A (ja) * 2004-03-11 2007-10-11 メリディアン メディカル テクノロジーズ,インコーポレーテッド 自動注射器用針/ハブ・アッセンブリ
JP4668260B2 (ja) * 2004-03-11 2011-04-13 メリディアン メディカル テクノロジーズ,インコーポレーテッド 自動注射器用針/ハブ・アッセンブリ
WO2006053568A1 (fr) 2004-11-22 2006-05-26 Borean Pharma Aps Antagonistes du tnf
WO2008064389A1 (fr) * 2006-11-28 2008-06-05 Morgan Meditech Inc Seringue rétractable
JP2015192925A (ja) * 2009-11-11 2015-11-05 ユニトラクト シリンジ プロプライエタリイ リミテッドUnitract Syringe Pty Ltd 格納式注射器、格納式注射器の交換式針アセンブリ、格納式注射器のバレル、格納式注射器キット、格納式注射器を操作する方法及びあらかじめ充填された注射器を製造する方法

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