WO2003090556A1 - Composition biologiquement active - Google Patents

Composition biologiquement active Download PDF

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Publication number
WO2003090556A1
WO2003090556A1 PCT/RU2003/000173 RU0300173W WO03090556A1 WO 2003090556 A1 WO2003090556 A1 WO 2003090556A1 RU 0300173 W RU0300173 W RU 0300173W WO 03090556 A1 WO03090556 A1 WO 03090556A1
Authority
WO
WIPO (PCT)
Prior art keywords
business
disease
treatment
kelp
patients
Prior art date
Application number
PCT/RU2003/000173
Other languages
English (en)
Russian (ru)
Inventor
Boris Nikolaevich Maslennikov
Nikolai Alexeevich Kostelev
Original Assignee
Boris Nikolaevich Maslennikov
Nikolai Alexeevich Kostelev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boris Nikolaevich Maslennikov, Nikolai Alexeevich Kostelev filed Critical Boris Nikolaevich Maslennikov
Priority to AU2003235559A priority Critical patent/AU2003235559A1/en
Publication of WO2003090556A1 publication Critical patent/WO2003090556A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • A23L17/30—Fish eggs, e.g. caviar; Fish-egg substitutes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives

Definitions

  • ⁇ ⁇ slednie g ⁇ dy v ⁇ all b ⁇ ly ⁇ em ⁇ beme is ⁇ lzuyu ⁇ sya for lechebn ⁇ - ⁇ ila ⁇ iches ⁇ g ⁇ power
  • the content of caviar in the finished product is 15–25%, see patent No. 2 116 039
  • a biologically active food supplement from laminaria is known, which is a direct product of laminar extract, which contains valuable amino acids 4.17-5.0% of weight of 200% of weight of 2005, of 100% of weight of 200% of weight of 2% % to absolute dry weight, see patent No. 2 134 522 on 08.20. 1999 year.
  • the benefits obtained by the claimed invention are ensured by the use of small amounts of biological resources for the use of mineral resources and the use of mining ⁇ dnim of as ⁇ e ⁇ v nas ⁇ yascheg ⁇ iz ⁇ b ⁇ e ⁇ eniya yavlyae ⁇ sya bi ⁇ l ⁇ giches ⁇ i a ⁇ ivnaya ⁇ m ⁇ zitsiya, vy ⁇ lnennaya ⁇ me in (a) ⁇ ischev ⁇ y d ⁇ bav ⁇ i, ⁇ m ⁇ ensi ⁇ uyuschey ne ⁇ va ⁇ u in ⁇ bychn ⁇ m ⁇ atsi ⁇ ne power The ned ⁇ s ⁇ a ⁇ in es ⁇ es ⁇ venny ⁇ ma ⁇ - and mi ⁇ elemen ⁇ a ⁇ , ⁇ a ⁇ a ⁇ e ⁇ ny ⁇ for s ⁇ s ⁇ ava lamina ⁇ ii and m ⁇ s ⁇ g ⁇ hedgehog.
  • the invention in the form of a food supplement, is obtained in this case, since it is general and pragmatic.
  • the food supplement has the composition indicated above (in wt.%): Shell laminaria 20.0 - 60.0; caviar of a sea urchin 6.6 - 20.0.
  • the compaction may be supplemented with physiologically acceptable additives necessary for its use, for example, a percentage of 1.2%; lactose - the rest.
  • An effective dose of the equipment for this aspect of the invention is no more than a few mg / kg of weight in the case of a single unit.
  • Another aspect of the invention is the composi- tion for the treatment and / or treatment of a disease in a patient in need of such treatment and / or treatment.
  • Compounds in this aspect of the invention provide for their own medical and / or medical treatment, the method mentioned above.
  • a part of this invention is an effective combination of components, which is at least a large 2 mg / kg or more.
  • a further aspect of the invention is the method of manufacturing a new biological active composition. This means that the equipment is prepared by the following methods: dried and grinded in the shells of sea kelp and fresh eggs of the sea hedgehog, obtained by freeze-drying, on the basis of 1 Then, the resulting mixture can be tested or encapsulated;
  • Palliatively acceptable additives can predominantly be calcium and lactose.
  • the content of the calcium mixture in the com- paction may be around 0.47-1.25 wt.%.
  • the claimed equipment may be performed in the form of a tablet by any known specialist in this area and include, in particular, the following components:
  • Kernels of tablets can contain (in wt%):
  • Tablets may contain (in wt%): Methyl cellulose (brands ⁇ -16) 4.5 ⁇ 0.8 Net oil 0.1 ⁇ 0.03
  • Titanium dioxide 0.4 ⁇ 0.2 5
  • the claimed offer may be placed in a box made from a physiologically acceptable biodegradable material.
  • a physiologically acceptable biodegradable material include all materials known in the field of pharmaceutical technology, in particular, for example, gelatin.
  • the invention may be used in the form of a food supplement in accordance with the invention.
  • the use of the food product in the form of a dietary supplement is effective in the dose of 1 mg / kg daily and during the course of a week.
  • the claimed equipment may be used in the quality of pharmaceutical and / or medicinal product.
  • the use of the drug in the form of a medicinal product is effective in the dose of at least about 2 mg / kg with a daily dose of over a week.
  • the use of the invention in the form of a medicinal product is useful in the treatment and / or treatment of a disease or a symptom of an ulcerative disease that is caused by an ulcerative disease; uterine gastritis; dyspepsia; asthenic syndrome, atherosclerosis of the aorta, coronary artery of the heart, vessels of the main brain, coronary artery disease, malignant disease; Gastric iron deficiency anemia, cancer of the mammary gland and intestine; an asynchronous state on the background of the chronic foci of infection in the host or on the site of the hepatobiliary system. Otherwise, the indicated combination is useful for radiation therapy of patients, patients with skin and neck shirts.
  • the method of the invention may optionally include a stage of operation or a stage of biologically active use in a sustainable environment.
  • lin ⁇ liev ⁇ y a complex of unique natural foods - biostimulating the regeneration of an organism, a full vitamin complex with an increased content of a vitamin, a gourmet, C, ⁇ 1, ⁇ 2, ⁇ 6, ⁇ 12 and others.
  • Minerals and minerals including iodine, zinc, iron, in an easily assimilable form.
  • Phospholipids and monoglycerides 22.85-44.33, including 10-36 lecithins
  • ch ⁇ ⁇ edlagae maya bi ⁇ l ⁇ giches ⁇ i a ⁇ ivnaya ⁇ m ⁇ zitsiya m ⁇ zhe ⁇ yavlya ⁇ sya ⁇ ila ⁇ iches ⁇ im s ⁇ eds ⁇ v ⁇ m zab ⁇ levany schi ⁇ vidn ⁇ y gland snizhae ⁇ v ⁇ zdeys ⁇ vie ⁇ azlichny ⁇ neblag ⁇ iya ⁇ ny ⁇ ⁇ a ⁇ v foreign s ⁇ edy on ⁇ ganizm ⁇ atsien ⁇ a (including in ⁇ m - chel ⁇ ve ⁇ a).
  • EXAMPLE 1 Biologically active composition containing (in wt.%): Short-sea kelp 20.0; spawning sea urchin 6.6; Calcium Calcium 0.47; lactose - the rest, was introduced by experimental animals (dogs weighing 2.8-3.4 kg) in a dose of 100 - 200 mg / kg. Research has shown a favorable impact on the heart-vessel and trial systems.
  • Biologically active composition containing (in wt.%): Short-sea kelp 60.0; ikruu sea urchin 20.0; Calcium 1.25; lactose - the rest, was introduced by experimental animals (children weighing 2.7-3.5 kg) at a dose of 100 - 200 mg / kg. Studies have shown the enhancement of regenerative processes and the application of a ⁇ arma. Example 3. The study and evaluation of the exchange processes and the system of the green and the non-invasive system were used in living models, generating 200 deaths of the deaths of the population (2). The administration was administered at a dose of 10-20 mg / kg. With this, biologically active was used. 10
  • Composition containing (in% by mass): the loss of marine kelp 40.0; ikruu sea urchin 13.3; calcium 0.65; lactose - the rest. Observation was performed for a month. Noticeable improvement in the exchange processes and the state of the domestic and non-emergency system.
  • Example 4 The effect of the invention on the state of the economy of the country and of hypoxia was investigated. With this, there was a statistically significant increase in the% of surviving animals under hygienic conditions.
  • Example 5 We studied the effect of the incidence of active components of the invention, and at the same time, found that there was a cessation of the occurrence of a recurring illness.
  • ⁇ a ⁇ im ⁇ b ⁇ az ⁇ m have ⁇ eblyavshi ⁇ ⁇ m ⁇ zitsiyu ⁇ iz ⁇ b ⁇ e ⁇ eniyu, ⁇ vysil ⁇ s not ⁇ l ⁇ note ⁇ amya ⁇ , s ⁇ s ⁇ ed ⁇ chenn ⁇ s ⁇ , n ⁇ and ums ⁇ vennaya ⁇ ab ⁇ s ⁇ s ⁇ bn ⁇ s ⁇ .
  • the content in the body at the time of the run was 7.42 ⁇ 0.8 mmol / l, and there was a decrease of 70.8. , 32 ⁇ 1.2 mmol / l, and beta-lipid to 52.2 units.
  • the consumption of a product by the invention favorably affects lipid metabolism, reducing the level of cholesterol in the body.
  • I ⁇ a, ⁇ izv ⁇ di maya of m ⁇ s ⁇ i ⁇ urchins - sy ⁇ tsa, is ⁇ lzuemaya in ⁇ m ⁇ zitstsii ⁇ iz ⁇ b ⁇ e ⁇ eniyu, s ⁇ ve ⁇ s ⁇ vue ⁇ ( ⁇ e ⁇ niches ⁇ ie usl ⁇ viya ⁇ ° 926 5-001-00472182-V4) medi ⁇ -bi ⁇ l ⁇ giches ⁇ im ⁇ eb ⁇ vaniyam and sani ⁇ a ⁇ nym n ⁇ mam ⁇ aches ⁇ va ⁇ d ⁇ v ⁇ ls ⁇ - venn ⁇ g ⁇ sy ⁇ ya and ⁇ ischevy ⁇ ⁇ du ⁇ v (u ⁇ ve ⁇ zhdenny ⁇ ⁇ inzd ⁇ av ⁇ m August 1, 1989 for ⁇ 5061-89).
  • the use of the investigated food product demonstrates a beneficial effect on the heart-vessel system and the function of the thyroid gland.
  • the recommendation is to recommend a pharmaceutical and nutritional supplement, a biological active nutrient:
  • the company was prepared for the reception, and was handled by the developers.
  • the studied product was prescribed for patients with a large difference of 1 mg / kg two times a day at the same time as the general treatment regimen was compared with severe, mild to severe cases.
  • the assessment of the medical effect of the medication was taken into account: a) its influence on the dynamics of the clinical manifestations of the disease (pain and disease), and the disease; b) the influence of it on the dynamics of the healing of the ulcerative defect of the mucous membrane and inflammatory changes in the gastrointestinal area in accordance with the data of the EPES c) the evaluation of the transmittance of the food.
  • Another group comprised five people aged 25 to 35 years, at which the incidence of an infection was unknown (there was a risk of infection).
  • the comparison group represented ten large ashenic syndromes of various origins, the maximum approximate to the primary group of clinics.
  • the treatment regimen is twice daily at a dose of 1 mg / kg for 15 days.
  • the above studies showed that all patients who had taken advantage of the competition rated it as having good taste and good taste. Only in two deteriorating cholecysts, when the food was eaten, did it cause a sense of discomfort and pressure in the process, and as a result, it was not endured.
  • the company is a valuable product, possessing good taste, convenience and wide range of medicinal properties. It stimulates the protective forces of the body, the corresponding, exchange processes, and has a hygienic-energetic effect. The regular application of the benefit of the welfare is reflected in the state and well-being of the oncological hospital Sh- ⁇ stage.
  • This product can be useful if: a) in the weakening and exhaustion of humanism; b) to improve the general physical condition; c) for the restoration of organism after prolonged and severe diseases; d) to prevent the rapid wilting and aging; e) to increase mental activity and workability; f) to improve the functions of the non-emergency, inter-court system, the exchange of substances.
  • Remote radiation therapy at the first stage consisted of a gamma of exposure of 2 G 5 5 times a week to reach a total focal dose of 20-30 G; at the second stage, the total dose to a point of 50-55 g.
  • Immediate radiation therapy was carried out at the KG-UU apparatus and consisted of 4-5 applications (40-50 Gy sum). Fifteen women received butter with cream from the 30th summer, and ten women made up a comparison group. The benefit of the company was equal to the benefits of radiation therapy and one more week after its termination.
  • ⁇ a ⁇ im ⁇ b ⁇ az ⁇ m ⁇ vedennye issled ⁇ vaniya identified d ⁇ s ⁇ a ⁇ chn ⁇ vys ⁇ uyu e ⁇ e ⁇ ivn ⁇ s ⁇ ⁇ m ⁇ zitsii, ⁇ aya ⁇ imenyalas with ⁇ iv ⁇ luchev ⁇ y aim at b ⁇ lny ⁇ ⁇ a ⁇ m ⁇ ela and shey ⁇ i ma ⁇ i, ⁇ busl ⁇ vlennym v ⁇ zdeys ⁇ viem b ⁇ lshi ⁇ luchevy ⁇ nag ⁇ uz ⁇ v ⁇ v ⁇ emya ⁇ mbini ⁇ vann ⁇ y luchev ⁇ y ⁇ e ⁇ a ⁇ ii.
  • the use of the company significantly reduced the frequency and severity of the total and local radiation treatment, and this ensured the overall success of the process.
  • the above clinical trial has shown that the investigated equipment has good taste and convenience.
  • the product does not cause any adverse events that are related to the gastrointestinal tract, and also does not cause an allergic reaction.
  • the claimed company has the advantage of being immune and stimulating, which makes it easier to use in the food industry.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention relève du domaine de l'industrie médicale, chimico-pharmaceutique et alimentaire. La composition biologiquement active de cette invention permet d'élargir la gamme des moyens thérapeutiques et/ou prophylactiques et des compléments alimentaires présentant un large spectre d'activités biologiques à double action, à savoir : a) l'alimentation d'appoint et l'élimination des déchets de l'organisme ; et b) le renforcement du traitement et/ou de la prévention de maladies. La composition biologiquement active de cette invention contient de la laminaire et des oeufs d'oursins et si nécessaire des excipients physiologiquement acceptables, en particulier le stéarate de calcium et le lactose.
PCT/RU2003/000173 2002-04-25 2003-04-17 Composition biologiquement active WO2003090556A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003235559A AU2003235559A1 (en) 2002-04-25 2003-04-17 Biologically active composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2002110993/13A RU2219806C1 (ru) 2002-04-25 2002-04-25 Пищевая биологически активная добавка "энерголам плюс"
RU2002110993 2002-04-25

Publications (1)

Publication Number Publication Date
WO2003090556A1 true WO2003090556A1 (fr) 2003-11-06

Family

ID=29268132

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2003/000173 WO2003090556A1 (fr) 2002-04-25 2003-04-17 Composition biologiquement active

Country Status (3)

Country Link
AU (1) AU2003235559A1 (fr)
RU (1) RU2219806C1 (fr)
WO (1) WO2003090556A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2113806C1 (ru) * 1997-02-05 1998-06-27 Ирина Дмитриевна Фадеева Пищевая биологически активная добавка
RU2116039C1 (ru) * 1997-07-08 1998-07-27 Александр Аркадьевич Макин Способ приготовления пищевого продукта с лечебно-профилактическими свойствами из гидробионтов
RU2134522C1 (ru) * 1998-02-25 1999-08-20 Товарищество с ограниченной ответственностью "Фитолон" Биологически активная пищевая добавка из ламинарии
RU2201116C1 (ru) * 2001-09-11 2003-03-27 Санталов Владимир Александрович Способ получения биологически активной добавки к пище и биологически активная добавка к пище, полученная этим способом

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2113806C1 (ru) * 1997-02-05 1998-06-27 Ирина Дмитриевна Фадеева Пищевая биологически активная добавка
RU2116039C1 (ru) * 1997-07-08 1998-07-27 Александр Аркадьевич Макин Способ приготовления пищевого продукта с лечебно-профилактическими свойствами из гидробионтов
RU2134522C1 (ru) * 1998-02-25 1999-08-20 Товарищество с ограниченной ответственностью "Фитолон" Биологически активная пищевая добавка из ламинарии
RU2201116C1 (ru) * 2001-09-11 2003-03-27 Санталов Владимир Александрович Способ получения биологически активной добавки к пище и биологически активная добавка к пище, полученная этим способом

Also Published As

Publication number Publication date
AU2003235559A1 (en) 2003-11-10
RU2219806C1 (ru) 2003-12-27

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