WO2003080542A3 - Verfahren zur herstellung von 3-hydroxy-2-methylbenzoesäure - Google Patents

Verfahren zur herstellung von 3-hydroxy-2-methylbenzoesäure Download PDF

Info

Publication number
WO2003080542A3
WO2003080542A3 PCT/EP2003/002415 EP0302415W WO03080542A3 WO 2003080542 A3 WO2003080542 A3 WO 2003080542A3 EP 0302415 W EP0302415 W EP 0302415W WO 03080542 A3 WO03080542 A3 WO 03080542A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydroxy
methylbenzoic acid
producing
sulfonation
alkalis
Prior art date
Application number
PCT/EP2003/002415
Other languages
English (en)
French (fr)
Other versions
WO2003080542A2 (de
Inventor
Friedrich Mueller-Hauck
Johannes Scherer
Gerhard Schroeder
Horst Behre
Original Assignee
Bayer Chemicals Ag
Friedrich Mueller-Hauck
Johannes Scherer
Gerhard Schroeder
Horst Behre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Chemicals Ag, Friedrich Mueller-Hauck, Johannes Scherer, Gerhard Schroeder, Horst Behre filed Critical Bayer Chemicals Ag
Priority to AU2003218717A priority Critical patent/AU2003218717A1/en
Priority to US10/507,875 priority patent/US20050222455A1/en
Priority to EP03711957A priority patent/EP1490319A2/de
Publication of WO2003080542A2 publication Critical patent/WO2003080542A2/de
Publication of WO2003080542A3 publication Critical patent/WO2003080542A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
    • C07C303/06—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with sulfuric acid or sulfur trioxide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/31—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation of cyclic compounds with ring-splitting
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von 3-Hydroxy-2-methylbenzoesäure bzw. Lösungen enthaltend Salze der 3-Hydroxy-2-methylbenzoesäure ausgehend von Naphthalin, das im Wesentlichen die Schritte Sulfonierung, Umsetzung mit Alkalien bei hohen Temperaturen und die vorteilhafte Aufarbeitung der resultierenden Reaktionsmischung umfasst.
PCT/EP2003/002415 2002-03-22 2003-03-10 Verfahren zur herstellung von 3-hydroxy-2-methylbenzoesäure WO2003080542A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2003218717A AU2003218717A1 (en) 2002-03-22 2003-03-10 Method for producing 3-hydroxy-2-methylbenzoic acid
US10/507,875 US20050222455A1 (en) 2002-03-22 2003-03-10 Method for producing 3-hydroxy-2-methylbenzoic acid
EP03711957A EP1490319A2 (de) 2002-03-22 2003-03-10 Verfahren zur herstellung von 3-hydroxy-2-methylbenzoes ure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10212885.5 2002-03-22
DE10212885A DE10212885A1 (de) 2002-03-22 2002-03-22 Verfahren zur Herstellung von 3-Hydroxy-2-methylbenzoesäure

Publications (2)

Publication Number Publication Date
WO2003080542A2 WO2003080542A2 (de) 2003-10-02
WO2003080542A3 true WO2003080542A3 (de) 2004-01-15

Family

ID=27798088

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/002415 WO2003080542A2 (de) 2002-03-22 2003-03-10 Verfahren zur herstellung von 3-hydroxy-2-methylbenzoesäure

Country Status (6)

Country Link
US (1) US20050222455A1 (de)
EP (1) EP1490319A2 (de)
CN (1) CN1642895A (de)
AU (1) AU2003218717A1 (de)
DE (1) DE10212885A1 (de)
WO (1) WO2003080542A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1371626A3 (de) * 2002-06-13 2004-07-21 Bayer Chemicals AG Verfahren zur Herstellung von 3-Alkoxy-2-methylbenzoesäuren
CN114349627A (zh) * 2022-01-25 2022-04-15 山东友道化学有限公司 一种2-甲基-3-羟基苯甲酸的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE91201C (de) *
EP0639559A1 (de) * 1993-08-19 1995-02-22 Rohm And Haas Company Die Herstellung von 1,2-Diacyl-2-(t-alkyl)-Hydrazinen
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853337A1 (de) * 1978-12-09 1980-06-26 Bayer Ag Neue sulfierungsprodukte des naphthalins, verfahren zu ihrer herstellung und verwendung
DE2901178A1 (de) * 1979-01-13 1980-07-24 Bayer Ag Verfahren zur herstellung von naphthalin-1,3,5-trisulfonsaeure
DE19704885C1 (de) * 1997-02-11 1998-06-10 Clariant Gmbh Verfahren zur Herstellung von 3-Hydroxy-2-methylbenzoesäure und 3-Acetoxy-2-methylbenzoesäure
DE19730848A1 (de) * 1997-07-18 1999-01-21 Bayer Ag Verfahren zur Herstellung von 3-Hydroxy-2-methylbenzoesäure

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE91201C (de) *
EP0639559A1 (de) * 1993-08-19 1995-02-22 Rohm And Haas Company Die Herstellung von 1,2-Diacyl-2-(t-alkyl)-Hydrazinen
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors

Also Published As

Publication number Publication date
AU2003218717A8 (en) 2003-10-08
DE10212885A1 (de) 2003-10-02
US20050222455A1 (en) 2005-10-06
AU2003218717A1 (en) 2003-10-08
CN1642895A (zh) 2005-07-20
EP1490319A2 (de) 2004-12-29
WO2003080542A2 (de) 2003-10-02

Similar Documents

Publication Publication Date Title
EP2323204A4 (de) Elektrodenaktives material und verfahren zu seiner herstellung
WO2008088529A3 (en) Ordered mesoporous carbons and method for manufacturing same
WO2006055748A3 (en) Method for the preparation of sevoflurane
WO2002005782A3 (de) Stabile salze von o-acetylsalicylsäure mit basischen aminosäuren
WO2003003860A3 (en) Stabilized compositions and processes of their preparation
NZ601326A (en) Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone
MY153225A (en) Method for producing propylene oxide
WO2004032905A8 (en) Gabapentin tablets and methods for their preparation
PL1880989T3 (pl) Sposób wytwarzania diniotrotoluenu
TW200724495A (en) Nanowires and a method of the same
TWI365867B (en) Process for preparing cyclohexanone and cyclohexanol
AU2003264043A1 (en) Method of making mercaptoalkylalkoxysilanes
WO2003037843A3 (en) Preparation of amphetamines from phenylpropanolamines
TW200609210A (en) Preparation of acrylic acid by heterogeneously catalyzed gas phase partial oxidation of at least one c3 hydrocarbon precursor compound
EP1538174A3 (de) Verfahren zum Aufreinigen von Polyarylensulfiden
EP1266885A4 (de) Verfahren zur herstellung von 2-hydroxy-4-methylthiobuttersäure
IL188716A0 (en) Method for preparing 4??-amino-4'-dimethyl-4-
EP1860085A4 (de) Verfahren zur synthese einer verbindung
WO2008077035A3 (en) Processes for the preparation of levetiracetam
WO2003080542A3 (de) Verfahren zur herstellung von 3-hydroxy-2-methylbenzoesäure
WO2005037965A3 (en) Engine oil additive
WO2007149305A3 (en) Improved oxidation process with enhanced safety useful in the manufacture of moxidectin by means of stabilised 2-iodoxybenzoic acid (sibx)
WO2006086602A3 (en) Improved process for the preparation of 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine
PT1289930E (pt) Processo para produzir acido 5-aminosalicilico
WO2002008443A1 (fr) Dispositif destine a marquer une proteine au moyen d'un systeme de synthese de proteine acellulaire d'embryon de ble

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003711957

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2512/DELNP/2004

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 10507875

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 20038066270

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2003711957

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Ref document number: JP