WO2003053497A1 - Behälter enthaltend mindestens zwei feststoffe und dessen verwendung - Google Patents

Behälter enthaltend mindestens zwei feststoffe und dessen verwendung Download PDF

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Publication number
WO2003053497A1
WO2003053497A1 PCT/EP2002/013334 EP0213334W WO03053497A1 WO 2003053497 A1 WO2003053497 A1 WO 2003053497A1 EP 0213334 W EP0213334 W EP 0213334W WO 03053497 A1 WO03053497 A1 WO 03053497A1
Authority
WO
WIPO (PCT)
Prior art keywords
container according
solids
container
solid
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/013334
Other languages
German (de)
English (en)
French (fr)
Inventor
François DUMONT D'AYOT
Stéphany DUPLANIL
Thomas Graf
Philippe Laffay
Thomas Wild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Medical Care Deutschland GmbH
Original Assignee
Fresenius Medical Care Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/498,004 priority Critical patent/US7311886B2/en
Priority to CA002465824A priority patent/CA2465824A1/en
Priority to KR10-2004-7007191A priority patent/KR20040065217A/ko
Priority to AU2002356736A priority patent/AU2002356736B2/en
Priority to JP2003554253A priority patent/JP2005512688A/ja
Priority to EP02805294A priority patent/EP1458433B1/de
Priority to BRPI0214597A priority patent/BRPI0214597B8/pt
Priority to DE50214432T priority patent/DE50214432D1/de
Application filed by Fresenius Medical Care Deutschland GmbH filed Critical Fresenius Medical Care Deutschland GmbH
Priority to AT02805294T priority patent/ATE467432T1/de
Publication of WO2003053497A1 publication Critical patent/WO2003053497A1/de
Anticipated expiration legal-status Critical
Priority to US11/979,734 priority patent/US20080135480A1/en
Priority to US12/003,056 priority patent/US20080149515A1/en
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1666—Apparatus for preparing dialysates by dissolving solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1668—Details of containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1668—Details of containers
    • A61M1/167—Flexible packaging for solid concentrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • B65D81/20—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient under vacuum or superatmospheric pressure, or in a special atmosphere, e.g. of inert gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders

Definitions

  • the invention relates to a container with at least one inlet and / or outlet, which contains at least two different solids arranged in layers, and to the use of the container for producing a liquid dialysate.
  • Dialysis is used to treat a patient suffering from renal insufficiency. This is done either in the peritoneum or by extracorporeal dialysis or filtration of the blood. Both methods have in common that dialysis fluids or dialysates absorb the metabolites. These dialysates usually contain a high content of sodium chloride and other electrolytes such as calcium or potassium chloride, a buffer substance such as bicarbonate or acetate as well as acid for the production of a physiological pH and optionally glucose as an osmotic.
  • Either finished dialysates are delivered or dialysates made from concentrates - including solid concentrates - are produced on site.
  • solids offer the advantage of the small pack volume and light weight.
  • the solids also have disadvantages - for example, the electrolyte salts are highly hygroscopic - the tendency is only to offer solid components for dialysate production.
  • the solids are usually salts or crystals, which can be in powder or granular form.
  • EP 0 287 987 describes a mixture of granules of the ionic components which are necessary for the preparation of dialysate.
  • DE 43 03 372 describes a bag for holding solid or liquid concentrate, usually bicarbonate, which is used for the production of dialysate and is coupled directly to a dialysis machine.
  • Characteristic of the invention is the layer-by-layer storage of at least two solids within a container.
  • the solids should preferably be components for a dialysate and are then in the form of powder, crystal or granules, since the dialysate components are produced from salts or glucose.
  • the contained solids can, but need not, be water-soluble. In the case of solids that are to form components for a dialysate, they are of course water-soluble. Furthermore, the use of such a container for the production of a diaysate is claimed.
  • the layers must be spaced apart from one another according to the invention. This can be done either by means of a separation unit, for example a loose film, or another solid component.
  • the components which are incompatible with one another are preferably separated from one another by a layer of a further, third component which is itself compatible with each of the two other components.
  • Compatible is defined as mutually not changing their chemical and / or physical properties, incompatible or incompatible accordingly vice versa. This is understood to mean that the container is also exposed to a long storage period or to extreme environmental conditions, such as during sterilization.
  • a third solid this can be used, for example, as small polymer beads be formed which are insoluble even in water, while the other solids are water soluble.
  • the third solid is a further component for producing a dialysate, which is then particularly preferably in the form of granules, powder or crystal and is likewise water-soluble.
  • components used to make dialysate are electrolytes, acids, sodium chloride, sodium bicarbonate and glucose. Of these substances, sodium bicarbonate and glucose, for example, are not compatible with each other. Therefore, according to the invention, a layer of sodium chloride is filled between the layer of sodium bicarbonate and the layer of glucose.
  • solid cartridge or flexible bag is conceivable as a container, which should be made from a material that is also compatible with its ingredients.
  • solid cartridges made of polycarbonate or flexible bags made of polyvinylpyrrolidone were mainly provided. However, these are increasingly being replaced by polyolefins, in particular polypropylene and polyethylene in connection with synthetic rubbers.
  • Special coatings, which additionally offer a gas barrier or water vapor barrier, special compatibility or similar advantages, have been described in numerous numbers in the prior art.
  • the container should have at least one inlet so that it can be filled with the components. According to the invention, this inlet can also be used as an outlet at the same time. However, it is also conceivable to provide inlets and outlets separately and / or to provide several inlets or outlets. These containers can also have connections such as injection points, ventilation devices or the like.
  • the solids are filled into the container in layers. So that the layers do not slip during transport, it is advantageous to fix the layers. It is conceivable to place a cover plate on the solid press layers that can be locked. However, it is particularly advantageous to remove unnecessary gases or liquids from the container, for example by suction.
  • the preferred embodiment of the invention is a flexible bag, in which a vacuum is drawn after the solids have been filled in layers by means of a pump and which is then sealed airtight. It should be noted that a completely air-free space can never be created, which is why the correct description describes an interior of the container that contains as little gas or liquid as possible. Likewise, the embodiment as a flexible bag is not absolutely necessary, but is particularly helpful if one wishes to fix the contained solids with the aid of a “vacuum pack”.
  • the preferred embodiment is nevertheless a flexible container which is filled with as many as possible all the substances necessary for the production of a dialysate, but at least filled with solids which form a partial concentrate ,
  • a common partial concentrate is the use of the three substances bicarbonate, sodium chloride and glucose.
  • Glucose is subject to degradation if it comes into contact with an incompatible substance of basic character, here bicarbonate. This is particularly the case during hot steam sterilization.
  • the particularly preferred embodiment is a flexible bag with three layers of solids composed of glucose, sodium chloride and sodium bicarbonate, with sodium chloride forming the middle boundary layer and with the layers being fixed is formed by extracting the air inside.
  • Such a filled bag serves as a concentrate supply for the production of dialysate. It is particularly advantageous if the amount presented in the bag is just sufficient to produce exactly the amount of dialysate that is necessary and sufficient for dialysis.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Bag Frames (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Processing Of Solid Wastes (AREA)
PCT/EP2002/013334 2001-12-20 2002-11-27 Behälter enthaltend mindestens zwei feststoffe und dessen verwendung Ceased WO2003053497A1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
BRPI0214597A BRPI0214597B8 (pt) 2001-12-20 2002-11-27 recipiente compreendendo pelo menos uma entrada ou saída e contendo pelo menos dois sólidos diferentes solúveis na água afetando mutuamente suas propriedades químicas e/ou físicas para produzir um dialisato
KR10-2004-7007191A KR20040065217A (ko) 2001-12-20 2002-11-27 적어도 2개의 고체물질을 포함하는 용기 및 그의 이용
AU2002356736A AU2002356736B2 (en) 2001-12-20 2002-11-27 Container containing at least two solid materials, and use thereof
JP2003554253A JP2005512688A (ja) 2001-12-20 2002-11-27 少なくとも２つの固形物を収容する容器およびその使用方法
EP02805294A EP1458433B1 (de) 2001-12-20 2002-11-27 Behälter enthaltend mindestens zwei feststoffe und dessen verwendung
US10/498,004 US7311886B2 (en) 2001-12-20 2002-11-27 Container containing at least two solid materials, and use thereof
CA002465824A CA2465824A1 (en) 2001-12-20 2002-11-27 Container containing at least two solids and use thereof
DE50214432T DE50214432D1 (de) 2001-12-20 2002-11-27 Behälter enthaltend mindestens zwei feststoffe und dessen verwendung
AT02805294T ATE467432T1 (de) 2001-12-20 2002-11-27 Behälter enthaltend mindestens zwei feststoffe und dessen verwendung
US11/979,734 US20080135480A1 (en) 2001-12-20 2007-11-07 Container containing at least two solid materials, and use thereof
US12/003,056 US20080149515A1 (en) 2001-12-20 2007-12-19 Container containing at least two solids and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10162959.1 2001-12-20
DE10162959.1A DE10162959B4 (de) 2001-12-20 2001-12-20 Behälter enthaltend mindestens zwei Feststoffe und dessen Verwendung

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/979,734 Division US20080135480A1 (en) 2001-12-20 2007-11-07 Container containing at least two solid materials, and use thereof
US12/003,056 Continuation US20080149515A1 (en) 2001-12-20 2007-12-19 Container containing at least two solids and use thereof

Publications (1)

Publication Number Publication Date
WO2003053497A1 true WO2003053497A1 (de) 2003-07-03

Family

ID=7710177

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/013334 Ceased WO2003053497A1 (de) 2001-12-20 2002-11-27 Behälter enthaltend mindestens zwei feststoffe und dessen verwendung

Country Status (10)

Country Link
US (2) US7311886B2 (https=)
EP (1) EP1458433B1 (https=)
JP (1) JP2005512688A (https=)
KR (1) KR20040065217A (https=)
AT (1) ATE467432T1 (https=)
AU (1) AU2002356736B2 (https=)
BR (1) BRPI0214597B8 (https=)
CA (1) CA2465824A1 (https=)
DE (2) DE10162959B4 (https=)
WO (1) WO2003053497A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10162959B4 (de) * 2001-12-20 2017-10-12 Fresenius Medical Care Deutschland Gmbh Behälter enthaltend mindestens zwei Feststoffe und dessen Verwendung
US7736328B2 (en) 2007-07-05 2010-06-15 Baxter International Inc. Dialysis system having supply container autoconnection
PL2585023T3 (pl) * 2010-06-23 2019-12-31 Gambro Lundia Ab Przygotowanie roztworów medycznych ze sproszkowanego materiału
DE102010039489A1 (de) * 2010-08-18 2012-02-23 Fresenius Medical Care Deutschland Gmbh Konzentrat
DE102011017048A1 (de) 2011-04-14 2012-10-18 Fresenius Medical Care Deutschland Gmbh Mehrkammercontainer zur Herstellung medizinischer Lösungen
AU2012272483B2 (en) 2011-06-24 2016-06-16 Lo, Richard W. C. Multi-container systems and uses thereof
US10636321B2 (en) 2014-07-02 2020-04-28 Gojo Industries, Inc. Methods and systems for improving hand hygiene
WO2016063811A1 (ja) * 2014-10-23 2016-04-28 ニプロ株式会社 透析用剤充填体
US10276029B2 (en) 2014-11-13 2019-04-30 Gojo Industries, Inc. Methods and systems for obtaining more accurate compliance metrics
US11583621B2 (en) 2015-05-27 2023-02-21 Triomed Ab Cartridge and apparatus for performing adsorption dialysis
WO2017193065A1 (en) 2016-05-06 2017-11-09 Gambro Lundia Ab Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation including testing thereof

Citations (8)

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Publication number Priority date Publication date Assignee Title
US3669880A (en) * 1969-06-30 1972-06-13 Cci Aerospace Corp Recirculation dialysate system for use with an artificial kidney machine
EP0287987A1 (en) 1987-04-23 1988-10-26 L.B.S. S.r.l. LABORATORIO BIOCHIMICO SPERIMENTALE Analgesic and antiinflammatory pharmaceutical compositions containing a naphthyl-acetic acid derivative
WO1990013323A1 (en) * 1989-05-01 1990-11-15 Baxter International Inc. Composition of beneficial agent and method for administering the same by controlled dissolution
DE4303372A1 (de) 1993-02-05 1994-08-11 Fresenius Ag Beutel zur Aufnahme von Konzentrat
JPH0940562A (ja) * 1995-08-02 1997-02-10 Tomita Seiyaku Kk 固形透析用剤及びその製造方法
US5616305A (en) * 1994-06-24 1997-04-01 Fresenius Ag Flexible medical hemodialysis packaging unit for the production of concentrated dialysis solution including a device for the same
WO2000057833A1 (en) * 1999-03-25 2000-10-05 Gambro Lundia Ab Method and supply bag for providing a medical solution
WO2001060428A1 (en) * 2000-02-16 2001-08-23 Teijin Limited Dialyzing fluid preparing device and powdery dialyzing fluid preparing chemical

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DE3539619C1 (en) * 1985-11-08 1987-04-30 Bayer Ag Packaging for granular or small-grain products with a high degree of purity, and method for filling, transporting and emptying the packaging
FR2614219B1 (fr) 1987-04-23 1993-07-09 Materiels Annexes Dialyse Procede de fabrication de granules destines a la preparation de solutions de dialyse et installation pour sa mise en oeuvre.
US5217854A (en) * 1990-05-10 1993-06-08 Fuji Photo Film Co., Ltd. Vacuum packaged color developing composition
FR2666739B1 (fr) * 1990-09-13 1998-01-02 Soludia Sa Dispositif pour la preparation extemporanee et en continu de dialysat.
JP3530235B2 (ja) * 1994-09-27 2004-05-24 味の素ファルマ株式会社 血液透析用剤
ATE178555T1 (de) 1994-12-09 1999-04-15 James Percival Robertson Aromatisierungsvorrichtung und verfahren
JPH08164198A (ja) * 1994-12-15 1996-06-25 Cytec Kk 固剤用容器が一体化の透析液調剤用固剤と溶解調剤装置
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US6274103B1 (en) * 1999-03-26 2001-08-14 Prismedical Corporation Apparatus and method for preparation of a peritoneal dialysis solution
US6489301B1 (en) * 1999-06-07 2002-12-03 Nipro Corporation Solid pharmaceutical preparation for dialysis and a process for producing the same
JP3714050B2 (ja) * 1999-09-07 2005-11-09 ニプロ株式会社 固形重曹透析用剤およびその製造方法
DE10162959B4 (de) * 2001-12-20 2017-10-12 Fresenius Medical Care Deutschland Gmbh Behälter enthaltend mindestens zwei Feststoffe und dessen Verwendung

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3669880A (en) * 1969-06-30 1972-06-13 Cci Aerospace Corp Recirculation dialysate system for use with an artificial kidney machine
EP0287987A1 (en) 1987-04-23 1988-10-26 L.B.S. S.r.l. LABORATORIO BIOCHIMICO SPERIMENTALE Analgesic and antiinflammatory pharmaceutical compositions containing a naphthyl-acetic acid derivative
WO1990013323A1 (en) * 1989-05-01 1990-11-15 Baxter International Inc. Composition of beneficial agent and method for administering the same by controlled dissolution
DE4303372A1 (de) 1993-02-05 1994-08-11 Fresenius Ag Beutel zur Aufnahme von Konzentrat
US5616305A (en) * 1994-06-24 1997-04-01 Fresenius Ag Flexible medical hemodialysis packaging unit for the production of concentrated dialysis solution including a device for the same
JPH0940562A (ja) * 1995-08-02 1997-02-10 Tomita Seiyaku Kk 固形透析用剤及びその製造方法
WO2000057833A1 (en) * 1999-03-25 2000-10-05 Gambro Lundia Ab Method and supply bag for providing a medical solution
WO2001060428A1 (en) * 2000-02-16 2001-08-23 Teijin Limited Dialyzing fluid preparing device and powdery dialyzing fluid preparing chemical
EP1177801A1 (en) * 2000-02-16 2002-02-06 Teijin Limited Dialyzing fluid preparing device and powdery dialyzing fluid preparing chemical

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 06 30 June 1997 (1997-06-30) *

Also Published As

Publication number Publication date
DE50214432D1 (de) 2010-06-24
DE10162959B4 (de) 2017-10-12
EP1458433A1 (de) 2004-09-22
US20050031509A1 (en) 2005-02-10
US7311886B2 (en) 2007-12-25
KR20040065217A (ko) 2004-07-21
CA2465824A1 (en) 2003-07-03
JP2005512688A (ja) 2005-05-12
BR0214597A (pt) 2004-11-03
ATE467432T1 (de) 2010-05-15
AU2002356736B2 (en) 2007-09-13
DE10162959A1 (de) 2003-07-17
US20080149515A1 (en) 2008-06-26
BRPI0214597B8 (pt) 2016-05-31
AU2002356736A1 (en) 2003-07-09
BR0214597B1 (pt) 2013-10-01
EP1458433B1 (de) 2010-05-12

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