WO2003051517A3 - Manipulierung kleinster flüssigkeitstropfen durch eine vielzahl von elektroden auf hydrophober oberfläche - Google Patents

Manipulierung kleinster flüssigkeitstropfen durch eine vielzahl von elektroden auf hydrophober oberfläche Download PDF

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Publication number
WO2003051517A3
WO2003051517A3 PCT/EP2002/014393 EP0214393W WO03051517A3 WO 2003051517 A3 WO2003051517 A3 WO 2003051517A3 EP 0214393 W EP0214393 W EP 0214393W WO 03051517 A3 WO03051517 A3 WO 03051517A3
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WO
WIPO (PCT)
Prior art keywords
electrodes
minuscule
hydrophobic surface
manipulation
fluid drops
Prior art date
Application number
PCT/EP2002/014393
Other languages
English (en)
French (fr)
Other versions
WO2003051517A2 (de
Inventor
Karsten Reihs
Original Assignee
Sunyx Surface Nanotechnologies
Karsten Reihs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunyx Surface Nanotechnologies, Karsten Reihs filed Critical Sunyx Surface Nanotechnologies
Priority to US10/499,607 priority Critical patent/US20050142037A1/en
Priority to AU2002360996A priority patent/AU2002360996A1/en
Priority to EP02795212A priority patent/EP1458487A2/de
Publication of WO2003051517A2 publication Critical patent/WO2003051517A2/de
Publication of WO2003051517A3 publication Critical patent/WO2003051517A3/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02N—ELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N11/00—Generators or motors not provided for elsewhere; Alleged perpetua mobilia obtained by electric or magnetic means
    • H02N11/006—Motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B01L2300/166—Suprahydrophobic; Ultraphobic; Lotus-effect
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Die vorliegende Erfindung betrifft eine Vorrichtung zum Manipulieren kleinster Flüssigkeitstropfen mit einer nach oben offenen ultraphoben Oberfläche, die im Bereich der hydrophoben Oberfläche ein Raster mit im wesentlichen gleichmässig verteilten Elektroden aufweist, mit denen jeweils ein elektrisches Feld erzeugbar ist und bei der gleichzeitig jeweils mindestens eine Elektrode von einer automatisierten Steuerungseinrichtung jeweils für einen bestimmeten Zeitraum mit einer elektrischen Spannung individuell so ansteuerbar ist, dass die Flüssigkeitstropfen auf der ultraphoben Oberfläche jeweils eine ganz bestimmte Bahn mit einer ganz bestimmten Geschwindigkeit durchlaufen.
PCT/EP2002/014393 2001-12-17 2002-12-17 Manipulierung kleinster flüssigkeitstropfen durch eine vielzahl von elektroden auf hydrophober oberfläche WO2003051517A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/499,607 US20050142037A1 (en) 2001-12-17 2002-12-17 Hydrophobic surface with a plurality of electrodes
AU2002360996A AU2002360996A1 (en) 2001-12-17 2002-12-17 Manipulation of minuscule fluid drops with a plurality of electrodes on a hydrophobic surface
EP02795212A EP1458487A2 (de) 2001-12-17 2002-12-17 Manipulierung kleinster flüssigkeitstropfen durch eine vielzahl von elektroden auf hydrophober oberfläche

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10162188A DE10162188A1 (de) 2001-12-17 2001-12-17 Hydrophobe Oberfläche mit einer Vielzahl von Elektroden
DE10162188.4 2001-12-17

Publications (2)

Publication Number Publication Date
WO2003051517A2 WO2003051517A2 (de) 2003-06-26
WO2003051517A3 true WO2003051517A3 (de) 2004-01-22

Family

ID=7709680

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/014393 WO2003051517A2 (de) 2001-12-17 2002-12-17 Manipulierung kleinster flüssigkeitstropfen durch eine vielzahl von elektroden auf hydrophober oberfläche

Country Status (5)

Country Link
US (1) US20050142037A1 (de)
EP (1) EP1458487A2 (de)
AU (1) AU2002360996A1 (de)
DE (1) DE10162188A1 (de)
WO (1) WO2003051517A2 (de)

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US7329545B2 (en) 2002-09-24 2008-02-12 Duke University Methods for sampling a liquid flow
US6911132B2 (en) 2002-09-24 2005-06-28 Duke University Apparatus for manipulating droplets by electrowetting-based techniques
US7048889B2 (en) 2004-03-23 2006-05-23 Lucent Technologies Inc. Dynamically controllable biological/chemical detectors having nanostructured surfaces
EP1859330B1 (de) 2005-01-28 2012-07-04 Duke University Vorrichtungen und verfahren zur manipulation von tropfen auf einer leiterplatte
KR101431775B1 (ko) 2005-05-11 2014-08-20 듀크 유니버서티 복수의 온도에서 생화학적 또는 화학적 반응을 수행하기위한 방법 및 장치
WO2007123908A2 (en) 2006-04-18 2007-11-01 Advanced Liquid Logic, Inc. Droplet-based multiwell operations
US8685344B2 (en) * 2007-01-22 2014-04-01 Advanced Liquid Logic, Inc. Surface assisted fluid loading and droplet dispensing
US8268246B2 (en) 2007-08-09 2012-09-18 Advanced Liquid Logic Inc PCB droplet actuator fabrication
FR2950133B1 (fr) * 2009-09-14 2011-12-09 Commissariat Energie Atomique Dispositif d'echange thermique a efficacite amelioree
US9513253B2 (en) 2011-07-11 2016-12-06 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based enzymatic assays

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EP0534002A1 (de) * 1991-08-07 1993-03-31 Naotake Mouri Verfahren zur Erstellung der Lage und der Anordnung eines sich in Untersuchung befindendem Objektes
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WO2002094442A1 (de) * 2001-05-22 2002-11-28 Infineon Technologies Ag Biosensorchip-dispensier-anordnung und verfahren zum dispensieren einer zu dispensierenden lösung unter verwendung der dispensier-anordnung auf einem biosensorchip

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Also Published As

Publication number Publication date
AU2002360996A1 (en) 2003-06-30
DE10162188A1 (de) 2003-06-18
AU2002360996A8 (en) 2003-06-30
US20050142037A1 (en) 2005-06-30
EP1458487A2 (de) 2004-09-22
WO2003051517A2 (de) 2003-06-26

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