WO2003048351A1 - 6-phosphogluconate dehydrogenase mutee - Google Patents

6-phosphogluconate dehydrogenase mutee Download PDF

Info

Publication number
WO2003048351A1
WO2003048351A1 PCT/JP2002/012661 JP0212661W WO03048351A1 WO 2003048351 A1 WO2003048351 A1 WO 2003048351A1 JP 0212661 W JP0212661 W JP 0212661W WO 03048351 A1 WO03048351 A1 WO 03048351A1
Authority
WO
WIPO (PCT)
Prior art keywords
amino acid
dna
microorganism
phosphogluconate dehydrogenase
polypeptide
Prior art date
Application number
PCT/JP2002/012661
Other languages
English (en)
French (fr)
Inventor
Masato Ikeda
Junko Ohnishi
Satoshi Mitsuhashi
Keiko Ochiai
Original Assignee
Kyowa Hakko Kogyo Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19177880&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003048351(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kogyo Co., Ltd. filed Critical Kyowa Hakko Kogyo Co., Ltd.
Priority to DE60231333T priority Critical patent/DE60231333D1/de
Priority to JP2003549530A priority patent/JP4074251B2/ja
Priority to AU2002349753A priority patent/AU2002349753A1/en
Priority to US10/497,502 priority patent/US7524667B2/en
Priority to EP02781875.6A priority patent/EP1462516B2/en
Publication of WO2003048351A1 publication Critical patent/WO2003048351A1/ja
Priority to US12/430,592 priority patent/US7989191B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/10Citrulline; Arginine; Ornithine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227Tryptophan

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PCT/JP2002/012661 2001-12-03 2002-12-03 6-phosphogluconate dehydrogenase mutee WO2003048351A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE60231333T DE60231333D1 (de) 2001-12-03 2002-12-03 Mutierte 6-phosphogluconat-dehydrogenase
JP2003549530A JP4074251B2 (ja) 2001-12-03 2002-12-03 変異型6−ホスホグルコン酸デヒドロゲナーゼ
AU2002349753A AU2002349753A1 (en) 2001-12-03 2002-12-03 Mutated 6-phosphogluconate dehydrogenase
US10/497,502 US7524667B2 (en) 2001-12-03 2002-12-03 Mutated 6-phosphogluconate dehydrogenase
EP02781875.6A EP1462516B2 (en) 2001-12-03 2002-12-03 Mutated 6-phosphogluconate dehydrogenase
US12/430,592 US7989191B2 (en) 2001-12-03 2009-04-27 Mutant 6-phosphogluconate dehydrogenase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001368264 2001-12-03
JP2001-368264 2001-12-03

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10497502 A-371-Of-International 2002-12-03
US12/430,592 Division US7989191B2 (en) 2001-12-03 2009-04-27 Mutant 6-phosphogluconate dehydrogenase

Publications (1)

Publication Number Publication Date
WO2003048351A1 true WO2003048351A1 (fr) 2003-06-12

Family

ID=19177880

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/012661 WO2003048351A1 (fr) 2001-12-03 2002-12-03 6-phosphogluconate dehydrogenase mutee

Country Status (7)

Country Link
US (2) US7524667B2 (ja)
EP (1) EP1462516B2 (ja)
JP (1) JP4074251B2 (ja)
AT (1) ATE423843T1 (ja)
AU (1) AU2002349753A1 (ja)
DE (1) DE60231333D1 (ja)
WO (1) WO2003048351A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9796991B2 (en) 2014-02-14 2017-10-24 Institute Of Microbiology, Chinese Academy Of Sciences Recombinant strain producing L-amino acids, constructing method therefor and method for producing L-amino acids

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005032426A1 (de) * 2004-12-18 2006-06-22 Degussa Ag Allele des gnd-Gens aus coryneformen Bakterien
WO2013158749A2 (en) * 2012-04-17 2013-10-24 Gevo, Inc. Engineered microorganisms with improved growth properties
CN108893502A (zh) * 2018-06-28 2018-11-27 无锡晶海氨基酸股份有限公司 一种提高l-异亮氨酸产量的方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011985A1 (fr) * 1993-10-28 1995-05-04 Ajinomoto Co., Inc. Procede de production d'une substance
JPH09224662A (ja) * 1996-02-23 1997-09-02 Mitsubishi Chem Corp 6−ホスホグルコン酸デヒドロゲナーゼおよびそれをコードするdna
WO2000034484A1 (en) * 1998-12-08 2000-06-15 Children's Hospital And Regional Medical Center Polymorphic loci that differentiate escherichia coli 0157:h7 from other strains
WO2001004325A1 (en) * 1999-07-09 2001-01-18 Degussa Ag Nucleotide sequences for the tal gene
EP1108790A2 (en) 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Novel polynucleotides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162618A (en) * 1998-04-10 2000-12-19 Smithkline Beecham Corporation 6-phosphogluconate dehydrogenase of Streptococcus pneumoniae
EP1227152A1 (en) 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Bacterial strain and genome of bifidobacterium
DE10154270A1 (de) * 2001-11-05 2003-05-15 Basf Ag Gene die für Kohlenstoffmetabolismus- und Energieproduktion-Proteine codieren

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011985A1 (fr) * 1993-10-28 1995-05-04 Ajinomoto Co., Inc. Procede de production d'une substance
JPH09224662A (ja) * 1996-02-23 1997-09-02 Mitsubishi Chem Corp 6−ホスホグルコン酸デヒドロゲナーゼおよびそれをコードするdna
WO2000034484A1 (en) * 1998-12-08 2000-06-15 Children's Hospital And Regional Medical Center Polymorphic loci that differentiate escherichia coli 0157:h7 from other strains
WO2001004325A1 (en) * 1999-07-09 2001-01-18 Degussa Ag Nucleotide sequences for the tal gene
EP1108790A2 (en) 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Novel polynucleotides

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
GENE, vol. 38, 1985, pages 275
GENETICS, vol. 39, 1954, pages 440
J. MOL. BIOL., vol. 16, 1966, pages 118
J. MOL. BIOL., vol. 166, 1983, pages 1
J. MOL. BIOL., vol. 215, 1990, pages 403
METHODS IN ENZYMOLOGY, vol. 183, 1990, pages 63 - 98
SCIENCE, vol. 222, 1983, pages 778
STRATEGIES, vol. 5, 1992, pages 81

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9796991B2 (en) 2014-02-14 2017-10-24 Institute Of Microbiology, Chinese Academy Of Sciences Recombinant strain producing L-amino acids, constructing method therefor and method for producing L-amino acids

Also Published As

Publication number Publication date
EP1462516B1 (en) 2009-02-25
JP4074251B2 (ja) 2008-04-09
DE60231333D1 (de) 2009-04-09
JPWO2003048351A1 (ja) 2005-04-14
EP1462516A1 (en) 2004-09-29
US20050079586A1 (en) 2005-04-14
US7989191B2 (en) 2011-08-02
ATE423843T1 (de) 2009-03-15
US20100120088A1 (en) 2010-05-13
US7524667B2 (en) 2009-04-28
AU2002349753A1 (en) 2003-06-17
EP1462516A4 (en) 2006-07-26
EP1462516B2 (en) 2013-04-17

Similar Documents

Publication Publication Date Title
EP0889133A3 (en) Process for producing microbial transglutaminase
BRPI0515788A (pt) alelos do gene gnd de bactérias corineformes
EP0832974A3 (en) Alcohol-aldehyd-dehydrogenases
CA2252493A1 (en) .beta.-galactoside - .alpha. 2,6-sialyltransferase gene
JP5516664B2 (ja) N−アセチル−(R,S)−β−アミノ酸アシラーゼ遺伝子
AU9086398A (en) G protein chimeras
AU2099301A (en) Method for obtaining proteins having improved functional characteristics
AU2001274537A1 (en) Novel glucose-6-phosphate dehydrogenase
WO2004029202A3 (en) Microbial trypsin variants having chymotrypsin activity and nucleic acids encoding same
EP1335020A4 (en) POLYPEPTIDE WITH ALPHA-ISOMALTOSYL TRANSFERASE ACTIVITY
WO2003048351A1 (fr) 6-phosphogluconate dehydrogenase mutee
CA2253021A1 (en) New mutants of formate dehydrogenase from candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases
US6890746B1 (en) Gene participating in the production of homo-glutamic acid and utilization thereof
CA2422295A1 (en) A gene of aluminum-activated malate transporter of a plant and a protein encoded by the gene
AU2001278683A1 (en) Novel carbonyl reductase, gene thereof and method of using the same
EP0828004A3 (en) Protein disulfide isomerase gene derived from strain of methylotrophic yeast
EP1262551A3 (en) A sorbitol dehydrogenase gene, a recombinant DNA, and a process for producing sorbitol dehydrogenase
CA2407059A1 (en) Novel (r)-2-hydroxy-3-phenylpropionic acid (d-phenyllactic acid) dehydrogenase and gene encoding the same
US7098018B2 (en) Aminopeptidase derived from bacillus licheniformis, gene encoding the aminopeptidase, expression vector containing the gene, transformant and method for preparation thereof
KR100477062B1 (ko) 바실러스 리케니포미스 유래의 신규한 아미노펩티다아제, 이를 코딩하는 유전자, 이 유전자를 포함하는 발현벡터, 이 발현벡터로 형질전환된 형질전환체 및 이를 이용하는 천연형 단백질의 제조방법
AU2003221437A1 (en) Mutated isopropylmalate isomerase
WO2002010383A1 (fr) Genes codant des proteines capables de regenerer la luciferine, adn recombine et methode de production de proteines capables de regenerer la luciferine
EP0897984A3 (en) D-Sorbitol dehydrogenase gene
EP1408107A3 (en) Chlorohydrin and hydroxycarboxylic ester asymmetric hydrolase gene
WO2000050868A3 (en) Generation of diagnostic tools to assay the human lhx3/p-lim/lim-3 factor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2003549530

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 10497502

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2002781875

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002781875

Country of ref document: EP