WO2003039407A2 - Procede de realisation de tuteur endovasculaire - Google Patents

Procede de realisation de tuteur endovasculaire Download PDF

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Publication number
WO2003039407A2
WO2003039407A2 PCT/GB2002/005076 GB0205076W WO03039407A2 WO 2003039407 A2 WO2003039407 A2 WO 2003039407A2 GB 0205076 W GB0205076 W GB 0205076W WO 03039407 A2 WO03039407 A2 WO 03039407A2
Authority
WO
WIPO (PCT)
Prior art keywords
stent
powder
manufacturing
laser
set forth
Prior art date
Application number
PCT/GB2002/005076
Other languages
English (en)
Other versions
WO2003039407A3 (fr
Inventor
Denis Dominic Healy
Original Assignee
Biocompatibles Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocompatibles Limited filed Critical Biocompatibles Limited
Priority to AU2002339126A priority Critical patent/AU2002339126A1/en
Publication of WO2003039407A2 publication Critical patent/WO2003039407A2/fr
Publication of WO2003039407A3 publication Critical patent/WO2003039407A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C10/00—Solid state diffusion of only metal elements or silicon into metallic material surfaces
    • C23C10/28—Solid state diffusion of only metal elements or silicon into metallic material surfaces using solids, e.g. powders, pastes
    • C23C10/30—Solid state diffusion of only metal elements or silicon into metallic material surfaces using solids, e.g. powders, pastes using a layer of powder or paste on the surface
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C24/00—Coating starting from inorganic powder
    • C23C24/02—Coating starting from inorganic powder by application of pressure only
    • C23C24/04—Impact or kinetic deposition of particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91525—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak

Definitions

  • the present invention relates generally to a manufacturing process for stents and stents formed by the manufacturing process, and in particular to methods and stents formed therefrom having increased radiopacity.
  • a stent is a medical device, usually a hollow tubular structure, which is inserted into a body lumen to provide support thereto.
  • Stents are well known in the art and there are many different types of stents available. Some are configured to be expanded after being located at a desired position in the lumen by an expansive force provided by an inflatable balloon. Others are delivered under compression so that, upon delivery they expand to provide the necessary supporting force. Others are made from heat-sensitive materials that expand at body temperature to provide the necessary supportive force. In recent times there has been a desire to form such stents from smaller and smaller quantities of material to provide greater flexibility, i.e., so that they are more flexible prior to delivery.
  • the present invention seeks to provide a method, and a stent produced therefrom, which increases the radiopacity of the stent without causing some of the problems associated with previous attempts at increasing radiopacity.
  • a method of manufacturing a stent 0 formed from a metal or metal alloy including the steps of applying a powder of a material having a higher radiopacity than that of the material from which the stent is formed to a region of the surface of the stent, and applying laser light to the surface having the radiopaque powder placed thereon such that the surface melts to incorporate the powder.
  • the preferred embodiment of the method may include the step of forming the 5 stent from stainless steel.
  • the powder may be formed from gold, platinum, tantalum, niobium, titanium or tungsten or a combination thereof.
  • the powder may be applied at the same time as applying the laser light.
  • the powder may also be applied by cold gas dynamic spraying.
  • the laser light may be generated by a YAG laser, a CO 2 laser, a Diode laser or Femto 0 laser.
  • the method may also include the step of cutting holes in the stent using the same laser either before or after fixing the powder to the surface of the stent.
  • the laser light may be applied to the powder at least twice in order to smooth the surface profile of the end product.
  • the present invention also may be used to manufacture a stent formed from a metal or
  • the stent having a powder impregnated in the surface thereof and the power being formed from a material having a radiopacity greater than that of the metal or metal alloy.
  • the stent of the present invention manufactured by applying a powder of a material having a higher radiopacity than that of the material from which the stent is formed to a region of the surface of the stent and applying laser light to the surface having the radiopaque powder
  • the powder is selected from the group including gold, platinum, tantalum, niobium, titanium or tungsten or a combination thereof.
  • Figure 1 is a side view of a known stent
  • Figure 2 is a side view of a stent manufactured in accordance with the present invention
  • FIGS 3A and 3B are schematic diagrams of the steps of the method of the present invention.
  • Figures 4A-4C are a series of images of the surface of stents produced in accordance with the method of the present invention.
  • a known stent 1 is shown.
  • the stent 1 has a body portion formed from a hollow tube of metal or metal alloy, usually stainless steel, as is well known in the art with cuts or openings in the surface of the stent 1 in a series of holes 2 which define struts 3.
  • the stent shown is a balloon-expandable stent 1 and the struts 3 are shaped so that, when a balloon 5 is inserted into the stent 1 and expanded, the stent 1 expands to form a rigid structure that can support a body lumen.
  • FIG. 2 shows a stent 1 according to the present invention in which components that correspond to those in the known stent 1 of figure 1 are numbered identically.
  • the stent 1 according to the invention has regions 4 of higher radiopacity 4 bonded on struts 3 at either end of the structure of the stent 1. These regions 4 of higher radiopacity enhance the visibility of the stent 1 under x-ray imaging so that, either during deployment or after deployment, a surgeon can more easily view the location of the stent 1.
  • Figure 3 A illustrates a preferred embodiment of the method of the present invention at various stages in the process of manufacturing the stent 1 of Figure 2.
  • a hollow tube of metal such as stainless steel, is provided with holes 2 etched or cut therein with a laser 6 which may be a YAG laser or, more cost effectively, a CO 2 laser.
  • Powdered radiopaque material is then applied either manually or automatically to at least a portion of the struts 3 at either end of the stent 1.
  • Laser light either from a separate laser light source or the same laser light source 6 that carried out the etching, is then applied so as to either melt the powder, or the surface of the struts 3, or both, when the light is applied in order to impregnate the surface of the stent 1 with the powder to form a radiopaque region 4.
  • the process is repeated in order to provide sufficient number of radiopaque regions 4 to ensure good visibility of the stent 1 in use.
  • the laser 6 may be applied a second time in order to smooth the overall surface.
  • Figure 3B illustrated another embodiment of the method of the present invention.
  • the powder is applied simultaneously with the laser light application.
  • This may involve use of a laser light source 6 with a surrounding powder dispensing nozzle 7 or a separate nozzle 7, both of which are shown in the figure.
  • the speed of the particles of the powder will preferably be in the range of 0.1 to 20m per second, providing flow rate for the powder particles which will be in the region of 1 to 1000 ⁇ g per second.
  • the powder is fed with an inert gas such as argon, helium or nitrogen.
  • the laser may be applied a second time, during which powder is not fed to the surface of the stent.
  • the method may employ one of a number of types of lasers, and in general it would be expected that the power of the laser would be no more than 50 Watts.
  • the method of the invention may be employed using a YAG welding laser with a Nb-Ti alloy powder, and Figure 4A shows a radiopaque region formed by such an approach.
  • a 250 am wide line of radiopaque region is formed which rises about 15 to 20 ⁇ m from of the surface of the stent 1.
  • the laser light was applied as spots which overlapped, and a higher repetition of the spots can increase the smoothness of the applied radiopaque region as can be seen from Figure 4B.
  • Figure 4C shows how the radiopaque region of Figure 4B can be further smoothed by passing the laser light over the region for a second time.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Metallurgy (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne un procédé permettant la réalisation d'un tuteur endovasculaire formé à partir d'un métal ou d'un alliage métallique, comprenant les étapes suivantes : application d'une poudre d'un matériau ayant une radiopacité supérieure à celle du matériau à partir duquel le tuteur endovasculaire est réalisé, sur une partie de la surface du tuteur endovasculaire ; et application de lumière laser sur la surface recouverte de la poudre radiopaque, de sorte que la poudre se trouve incorporée à la surface du tuteur endovasculaire. Le procédé peut également comprendre la formation dudit tuteur endovasculaire à partir d'acier inoxydable. De plus, la poudre peut être sélectionnée parmi le groupe comprenant l'or, le platine, le tantale, le niobium, le titane, ou le tungstène ou une combinaison de ceux-ci, et la lumière laser peut être produite par un laser à YAG, un laser à CO2, un laser à diode ou un femtolaser. De façon alternative, l'invention concerne un tuteur endovasculaire formé à partir d'un métal ou d'un alliage métallique et comprenant une poudre imprégnée à sa surface.
PCT/GB2002/005076 2001-11-09 2002-11-11 Procede de realisation de tuteur endovasculaire WO2003039407A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002339126A AU2002339126A1 (en) 2001-11-09 2002-11-11 Method for manufacturing a stent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0127033.9 2001-11-09
GBGB0127033.9A GB0127033D0 (en) 2001-11-09 2001-11-09 Stent manufacture

Publications (2)

Publication Number Publication Date
WO2003039407A2 true WO2003039407A2 (fr) 2003-05-15
WO2003039407A3 WO2003039407A3 (fr) 2003-11-27

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Country Status (3)

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AU (1) AU2002339126A1 (fr)
GB (1) GB0127033D0 (fr)
WO (1) WO2003039407A2 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10335192A1 (de) * 2003-07-30 2005-03-03 Phytis Medical Devices Gmbh Marker auf einem Stent
WO2005058537A2 (fr) * 2003-12-10 2005-06-30 Boston Scientific Limited Dispositifs medicaux et leurs procedes de fabrication
EP1674596A1 (fr) * 2004-12-21 2006-06-28 United Technologies Corporation Dépôts de projection à froid amélioré par laser
WO2006082170A1 (fr) * 2005-02-02 2006-08-10 Siemens Aktiengesellschaft Procede de pulverisation par gaz froid
WO2009059141A2 (fr) * 2007-11-02 2009-05-07 Boston Scientific Limited Stent avec matériau incorporé
WO2009059180A2 (fr) * 2007-11-02 2009-05-07 Boston Scientific Limited Prothèse endovasculaire
US7739781B2 (en) 1996-12-30 2010-06-22 Sorin Biomedica Cardio S.R.L Process for producing a stent for angioplasty
WO2011083321A1 (fr) * 2010-01-11 2011-07-14 Smith & Nephew Plc Dispositif médical et procédé correspondant
US8221822B2 (en) * 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2187988B1 (fr) 2007-07-19 2013-08-21 Boston Scientific Limited Endoprothese pourvue d'une surface anti-encrassement
EP2185103B1 (fr) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Revêtement pour un dispositif médical ayant une aire surfacique accrue
JP5581311B2 (ja) 2008-04-22 2014-08-27 ボストン サイエンティフィック サイムド，インコーポレイテッド 無機材料のコーティングを有する医療デバイス及びその製造方法
WO2009132176A2 (fr) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Dispositifs médicaux comportant des couches de particules inorganiques

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2551770A1 (fr) * 1983-09-14 1985-03-15 Honda Motor Co Ltd Procede de traitement de surface d'une piece metallique par refusion et produits obtenus
EP0824900A2 (fr) * 1996-08-22 1998-02-25 Advanced Cardiovascular Systems, Inc. Revêtement protecteur pour un Stent muni d'une couche radio-opaque intermédiaire
WO2001049340A1 (fr) * 1999-12-30 2001-07-12 Advanced Cardiovascular Systems, Inc. Endoprothese a enrobage opacifiant constitue de particules dans un liant
WO2002026162A2 (fr) * 2000-09-26 2002-04-04 Advanced Cardiovascular Systems, Inc. Procede de chargement d'une substance sur un dispositif implantable

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2551770A1 (fr) * 1983-09-14 1985-03-15 Honda Motor Co Ltd Procede de traitement de surface d'une piece metallique par refusion et produits obtenus
EP0824900A2 (fr) * 1996-08-22 1998-02-25 Advanced Cardiovascular Systems, Inc. Revêtement protecteur pour un Stent muni d'une couche radio-opaque intermédiaire
WO2001049340A1 (fr) * 1999-12-30 2001-07-12 Advanced Cardiovascular Systems, Inc. Endoprothese a enrobage opacifiant constitue de particules dans un liant
WO2002026162A2 (fr) * 2000-09-26 2002-04-04 Advanced Cardiovascular Systems, Inc. Procede de chargement d'une substance sur un dispositif implantable

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7946019B2 (en) 1996-12-30 2011-05-24 Sorin Biomedica Cardio S.R.L. Process for producing a stent for angioplasty
US7739781B2 (en) 1996-12-30 2010-06-22 Sorin Biomedica Cardio S.R.L Process for producing a stent for angioplasty
DE10335192A1 (de) * 2003-07-30 2005-03-03 Phytis Medical Devices Gmbh Marker auf einem Stent
WO2005058537A2 (fr) * 2003-12-10 2005-06-30 Boston Scientific Limited Dispositifs medicaux et leurs procedes de fabrication
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WO2003039407A3 (fr) 2003-11-27

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