WO2003031414A1 - Nouveau compose heterocyclique et agent anti-inflammatoire - Google Patents

Nouveau compose heterocyclique et agent anti-inflammatoire Download PDF

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Publication number
WO2003031414A1
WO2003031414A1 PCT/JP2002/010291 JP0210291W WO03031414A1 WO 2003031414 A1 WO2003031414 A1 WO 2003031414A1 JP 0210291 W JP0210291 W JP 0210291W WO 03031414 A1 WO03031414 A1 WO 03031414A1
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Prior art keywords
heterocyclic compound
inflammatory agent
novel heterocyclic
sulfur
alkyl
Prior art date
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PCT/JP2002/010291
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English (en)
French (fr)
Inventor
Masae Takagi
Keiichi Ishimitsu
Tadayuki Nishibe
Original Assignee
Nippon Soda Co.,Ltd.
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Filing date
Publication date
Application filed by Nippon Soda Co.,Ltd. filed Critical Nippon Soda Co.,Ltd.
Priority to US10/489,682 priority Critical patent/US20050032858A1/en
Priority to EP02800750A priority patent/EP1435353A4/en
Priority to JP2003534398A priority patent/JPWO2003031414A1/ja
Publication of WO2003031414A1 publication Critical patent/WO2003031414A1/ja

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/26—2-Pyrrolidones
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    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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PCT/JP2002/010291 2001-10-03 2002-10-02 Nouveau compose heterocyclique et agent anti-inflammatoire WO2003031414A1 (fr)

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US10/489,682 US20050032858A1 (en) 2001-10-03 2002-10-02 Novel heterocyclic compound and anti-inflamatory agent
EP02800750A EP1435353A4 (en) 2001-10-03 2002-10-02 NEW HETEROCYCLIC COMPOUND AND ANTI-INFLAMMATORY AGENT
JP2003534398A JPWO2003031414A1 (ja) 2001-10-03 2002-10-02 新規なヘテロ環化合物および抗炎症薬

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JP2001307301 2001-10-03

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WO2003106437A1 (en) * 2002-06-12 2003-12-24 The Board Of Trustees Of The University Of Illinois 2-oxazolidinones and their use as inhibitors of animal cell motility and growth
JP2016130309A (ja) * 2015-01-08 2016-07-21 住友化学株式会社 樹脂、レジスト組成物及びレジストパターンの製造方法
KR20190015232A (ko) * 2016-05-31 2019-02-13 키에시 파르마슈티시 엣스. 피. 에이. 인간 호중구 엘라스타제 억제제로서 이미다졸론 화합물

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AR057218A1 (es) 2005-12-15 2007-11-21 Astra Ab Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato
KR20080103584A (ko) * 2006-03-30 2008-11-27 아사히 가세이 파마 가부시키가이샤 치환 이환식 환상 유도체 및 그 용도
KR101269393B1 (ko) * 2008-04-28 2013-05-29 아사히 가세이 파마 가부시키가이샤 페닐프로피온산 유도체 및 이의 용도
WO2012041253A1 (en) * 2010-09-30 2012-04-05 Zhejiang Beta Pharma Inc. Compounds for increase of hdl-c level and uses thereof
WO2014099834A1 (en) * 2012-12-20 2014-06-26 Merck Sharp & Dohme Corp. Therapeutic thiazolidinone compounds
US20160152579A1 (en) * 2013-07-11 2016-06-02 Servicio Andaluz De Salud Oxazolidinone derivatives as ppar ligands
EP3402777B1 (en) * 2015-12-16 2023-12-13 Merck Sharp & Dohme Corp. Oxazolidinones as taro inhibitors
CN111499623B (zh) * 2020-04-01 2022-07-08 南京缘聚医药科技有限公司 一类非核苷抗肿瘤药物的噻唑酮脲衍生物及其药物用途
WO2021230710A1 (ko) * 2020-05-15 2021-11-18 (주)신테카바이오 신규 ido/tdo 억제제, 그의 항암 용도, 그의 항암 병용 요법

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US4442116A (en) * 1979-10-03 1984-04-10 Nippon Soda Company, Limited Heterocyclic compounds
US4804657A (en) * 1986-06-18 1989-02-14 Nippon Chemiphar Co., Ltd. Process for protection of brain cells
JPH08291155A (ja) * 1995-04-19 1996-11-05 Mitsui Toatsu Chem Inc チアゾリジン系殺菌剤
WO1999037630A1 (en) * 1998-01-23 1999-07-29 Versicor, Inc. Oxazolidinone combinatorial libraries, compositions and methods of preparation
WO2000037473A1 (en) * 1998-12-22 2000-06-29 Novartis Ag Epothilone derivatives and their use as antitumor agents

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106437A1 (en) * 2002-06-12 2003-12-24 The Board Of Trustees Of The University Of Illinois 2-oxazolidinones and their use as inhibitors of animal cell motility and growth
US7390826B2 (en) 2002-06-12 2008-06-24 The Board Of Trustees Of The University Of Illinois Inhibitors of animal cell motility and growth
JP2016130309A (ja) * 2015-01-08 2016-07-21 住友化学株式会社 樹脂、レジスト組成物及びレジストパターンの製造方法
KR20190015232A (ko) * 2016-05-31 2019-02-13 키에시 파르마슈티시 엣스. 피. 에이. 인간 호중구 엘라스타제 억제제로서 이미다졸론 화합물
JP2019520313A (ja) * 2016-05-31 2019-07-18 シエッシ ファーマスーティシ エス．ピー．エー． ヒト好中球エラスターゼ阻害剤としてのイミダゾロン化合物
JP6990663B2 (ja) 2016-05-31 2022-01-13 シエッシ ファーマスーティシ エス．ピー．エー． ヒト好中球エラスターゼ阻害剤としてのイミダゾロン化合物
KR102404031B1 (ko) 2016-05-31 2022-06-02 키에시 파르마슈티시 엣스. 피. 에이. 인간 호중구 엘라스타제 억제제로서 이미다졸론 화합물

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US20050032858A1 (en) 2005-02-10
JPWO2003031414A1 (ja) 2005-01-20
EP1435353A1 (en) 2004-07-07

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