WO2003027296A1 - Genes intervenant dans la synthese d'acide gras presentant une liaison double conjuguee trans-11-, cis-13-, et utilisation desdits genes - Google Patents

Genes intervenant dans la synthese d'acide gras presentant une liaison double conjuguee trans-11-, cis-13-, et utilisation desdits genes Download PDF

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Publication number
WO2003027296A1
WO2003027296A1 PCT/JP2002/009683 JP0209683W WO03027296A1 WO 2003027296 A1 WO2003027296 A1 WO 2003027296A1 JP 0209683 W JP0209683 W JP 0209683W WO 03027296 A1 WO03027296 A1 WO 03027296A1
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WO
WIPO (PCT)
Prior art keywords
fatty acid
double bond
base sequences
cis
trans
Prior art date
Application number
PCT/JP2002/009683
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English (en)
French (fr)
Inventor
Mari Osumi
Junko Murase
Jun Imamura
Original Assignee
Plantech Research Institute
Bio-Oriented Technology Research Advancement Institution
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plantech Research Institute, Bio-Oriented Technology Research Advancement Institution filed Critical Plantech Research Institute
Priority to EP02765609A priority Critical patent/EP1437412A4/en
Priority to US10/490,299 priority patent/US7402418B2/en
Publication of WO2003027296A1 publication Critical patent/WO2003027296A1/ja

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
PCT/JP2002/009683 2001-09-20 2002-09-20 Genes intervenant dans la synthese d'acide gras presentant une liaison double conjuguee trans-11-, cis-13-, et utilisation desdits genes WO2003027296A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02765609A EP1437412A4 (en) 2001-09-20 2002-09-20 GENES INVOLVED IN THE SYNTHESIS OF FATTY ACID WITH A TRANS-11, CIS-13-CONJUGATED DOUBLE BINDING AND USE THEREOF
US10/490,299 US7402418B2 (en) 2001-09-20 2002-09-20 Genes participating in the synthesis of fatty acid having trans-11-,cis-13-conjugated double bond and utilization thereof

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2001-286390 2001-09-20
JP2001286390 2001-09-20
JP2002-127810 2002-04-30
JP2002127810 2002-04-30
JP2002-226386 2002-08-02
JP2002-226387 2002-08-02
JP2002226387 2002-08-02
JP2002226386 2002-08-02

Publications (1)

Publication Number Publication Date
WO2003027296A1 true WO2003027296A1 (fr) 2003-04-03

Family

ID=27482567

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/009683 WO2003027296A1 (fr) 2001-09-20 2002-09-20 Genes intervenant dans la synthese d'acide gras presentant une liaison double conjuguee trans-11-, cis-13-, et utilisation desdits genes

Country Status (3)

Country Link
US (1) US7402418B2 (ja)
EP (1) EP1437412A4 (ja)
WO (1) WO2003027296A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005239704A (ja) * 2004-01-30 2005-09-08 Shokubutsu Kogaku Kenkyusho:Kk 脂肪蓄積抑制剤
WO2005070412A3 (en) * 2004-01-20 2005-11-10 Nutrition Therapeutics Inc Method of using punicic acid to enhance immune response and prevent metabolic disorders

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4019147B2 (ja) 2003-10-31 2007-12-12 独立行政法人農業生物資源研究所 種子特異的プロモーターおよびその利用
US20050159483A1 (en) 2004-01-20 2005-07-21 Josep Bassaganya-Riera Method of using punicic acid to enhance immune response and prevent metabolic disorders
US20080193550A1 (en) * 2004-05-11 2008-08-14 Fonterra Corporate Research And Development Limited Cla-Enriched Milkfat and Uses Thereof
EP2336782B1 (en) * 2006-03-24 2014-08-27 Metanomics GmbH Methods for predicting diabetes type II
EP2298883B1 (en) * 2008-05-28 2016-07-27 Kyoto University Novel selection marker gene and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000011176A2 (en) * 1998-08-20 2000-03-02 E.I. Du Pont De Nemours And Company Genes for plant fatty acid modifying enzymes associated with conjugated double bond formation
WO2000062772A1 (fr) * 1999-04-15 2000-10-26 Kaneka Corporation Agonistes du recepteur sensible a l'activateur du type peroxysome
WO2001016362A2 (de) * 1999-09-01 2001-03-08 Basf Aktiengesellschaft Fettsäure-desaturase-gen aus pflanzen
JP2002238566A (ja) * 2001-02-13 2002-08-27 Shokubutsu Kogaku Kenkyusho:Kk カタルピック酸及び/またはプニシック酸の合成に関与する遺伝子

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2293674A (en) 1941-06-04 1942-08-18 Dry Zero Corp Strip punching machine
US2421157A (en) 1942-01-20 1947-05-27 Emery Industries Inc Method of separating fatty acids
JPS58110600A (ja) 1981-12-25 1983-07-01 Kyowa Hakko Kogyo Co Ltd ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド
JP2564268B2 (ja) 1985-08-28 1996-12-18 協和醗酵工業株式会社 融合抗原ポリペプチド
JPH0322979A (ja) 1989-06-19 1991-01-31 Kyowa Hakko Kogyo Co Ltd 新規プラスミノーゲン活性化因子
US5850026A (en) * 1996-07-03 1998-12-15 Cargill, Incorporated Canola oil having increased oleic acid and decreased linolenic acid content
JP2000355538A (ja) 1999-04-15 2000-12-26 Kanegafuchi Chem Ind Co Ltd ペルオキシゾーム活性化剤応答性受容体アゴニスト
ATE455172T1 (de) 1999-08-16 2010-01-15 Du Pont Verfahren zur herstellung von calendulasäure, einer fettsäure mit delta-8,10,12 konjugierten doppelbindungen und dimorphekolinsäure, einer fettsäure mit einer 9-hydroxyl-gruppe und delta- 10,12 konjugierten doppelbindungen
DE10134660A1 (de) * 2001-07-20 2003-02-06 Basf Plant Science Gmbh Fettsäure-Desaturase-Gene aus Granatapfel und Verfahren zur Herstellung von ungesättigten Fettsäuren
GB0118935D0 (en) 2001-08-02 2001-09-26 Icgeb Xylanase production

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000011176A2 (en) * 1998-08-20 2000-03-02 E.I. Du Pont De Nemours And Company Genes for plant fatty acid modifying enzymes associated with conjugated double bond formation
WO2000062772A1 (fr) * 1999-04-15 2000-10-26 Kaneka Corporation Agonistes du recepteur sensible a l'activateur du type peroxysome
WO2001016362A2 (de) * 1999-09-01 2001-03-08 Basf Aktiengesellschaft Fettsäure-desaturase-gen aus pflanzen
JP2002238566A (ja) * 2001-02-13 2002-08-27 Shokubutsu Kogaku Kenkyusho:Kk カタルピック酸及び/またはプニシック酸の合成に関与する遺伝子

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HORNUNG E. ET AL.: "Formation of conjugated delta11delta13-double bonds by delta12-linoleic acid(1,4)-acyl-lipid-desaturase in pomegranate seeds", EUR. J. BIOCHEM., vol. 269, no. 19, October 2002 (2002-10-01), pages 4852 - 4859, XP002961719 *
See also references of EP1437412A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070412A3 (en) * 2004-01-20 2005-11-10 Nutrition Therapeutics Inc Method of using punicic acid to enhance immune response and prevent metabolic disorders
JP2005239704A (ja) * 2004-01-30 2005-09-08 Shokubutsu Kogaku Kenkyusho:Kk 脂肪蓄積抑制剤

Also Published As

Publication number Publication date
US20050108788A1 (en) 2005-05-19
US7402418B2 (en) 2008-07-22
EP1437412A1 (en) 2004-07-14
EP1437412A4 (en) 2005-02-02

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