WO2003020875A3 - Staphylococci surface-exposed immunogenic polypeptides - Google Patents

Staphylococci surface-exposed immunogenic polypeptides Download PDF

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Publication number
WO2003020875A3
WO2003020875A3 PCT/US2002/019224 US0219224W WO03020875A3 WO 2003020875 A3 WO2003020875 A3 WO 2003020875A3 US 0219224 W US0219224 W US 0219224W WO 03020875 A3 WO03020875 A3 WO 03020875A3
Authority
WO
WIPO (PCT)
Prior art keywords
staphylococci
immunogenic polypeptides
exposed
exposed immunogenic
isolating
Prior art date
Application number
PCT/US2002/019224
Other languages
French (fr)
Other versions
WO2003020875A2 (en
Inventor
David L Scott Jr
Original Assignee
Squared Biotechnologies Inc D
David L Scott Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squared Biotechnologies Inc D, David L Scott Jr filed Critical Squared Biotechnologies Inc D
Priority to AU2002353764A priority Critical patent/AU2002353764A1/en
Publication of WO2003020875A2 publication Critical patent/WO2003020875A2/en
Publication of WO2003020875A3 publication Critical patent/WO2003020875A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The present invention is directed to membrane-bound immunogenic polypeptides associated with Staphylococci. The invention also relates to methods for isolating these immunogenic polypeptides and their use for the production of antibodies effective against Staphylococci infection.
PCT/US2002/019224 2001-06-17 2002-06-17 Staphylococci surface-exposed immunogenic polypeptides WO2003020875A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002353764A AU2002353764A1 (en) 2001-06-17 2002-06-17 Staphylococci surface-exposed immunogenic polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29897501P 2001-06-17 2001-06-17
US60/298,975 2001-06-17

Publications (2)

Publication Number Publication Date
WO2003020875A2 WO2003020875A2 (en) 2003-03-13
WO2003020875A3 true WO2003020875A3 (en) 2003-10-23

Family

ID=23152805

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/019224 WO2003020875A2 (en) 2001-06-17 2002-06-17 Staphylococci surface-exposed immunogenic polypeptides

Country Status (2)

Country Link
AU (1) AU2002353764A1 (en)
WO (1) WO2003020875A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002316619A1 (en) * 2001-07-10 2003-01-29 D-Squared Biotechnologies, Inc. Antimicrobial nucleic acid antibodies, and materials and methods for making and using same
US8119147B2 (en) 2003-09-19 2012-02-21 Epitopix, Llc Compositions produced using enteric pathogens and methods of use
KR20070083638A (en) * 2004-09-08 2007-08-24 더 유니버시티 오브 웨스턴 온타리오 Screening assays for inhibitors of a staphylococcus aureus siderophore
RU2419628C2 (en) * 2004-09-22 2011-05-27 ГлаксоСмитКлайн Байолоджикалз с.а. Immunogenic composition for use in vaccination against staphylococci
AU2015258239B2 (en) * 2005-02-14 2017-08-17 Epitopix, Llc Polypeptides from staphylococcus aureus and methods of use
AU2012244060B2 (en) * 2005-02-14 2015-08-20 Epitopix, Llc Polypeptides from staphylococcus aureus and methods of use
WO2006088803A2 (en) 2005-02-14 2006-08-24 Epitopix, Llc Polypeptides from staphylococcus aureus and methods of use
NZ614557A (en) 2009-03-23 2015-03-27 Epitopix Llc Polypeptides and immunizing compositions containing gram positive polypeptides and methods of use
CN109248313B (en) 2009-04-14 2023-01-17 葛兰素史密丝克莱恩生物有限公司 Compositions for immunization against staphylococcus aureus
EP4227685A3 (en) * 2013-12-03 2024-02-28 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COURCOL ET AL.: "Siderophore production by staphylococcus aureus and identification of iron-regulated proteins", INFECT. IMMUN., vol. 65, no. 5, May 1997 (1997-05-01), pages 1944 - 1948, XP002964177 *
MODUN ET AL.: "Staphylococci express a receptor for human transferrin: identification of a 42-kilodalton cell wall transferrin-binding protein", INFECT. IMMUN., vol. 62, no. 9, September 1994 (1994-09-01), pages 3850 - 3858 *
MODUN ET AL.: "The staphylococcus aureus and staphylococcus epidermidis transferrin-binding proteins are expressed in vivo during infection", MICROBIOLOGY, vol. 144, 1998, pages 1005 - 1012, XP001084239 *

Also Published As

Publication number Publication date
WO2003020875A2 (en) 2003-03-13
AU2002353764A1 (en) 2003-03-18

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