WO2003037262A3 - Novel anit-infectives - Google Patents

Novel anit-infectives Download PDF

Info

Publication number
WO2003037262A3
WO2003037262A3 PCT/US2002/034655 US0234655W WO03037262A3 WO 2003037262 A3 WO2003037262 A3 WO 2003037262A3 US 0234655 W US0234655 W US 0234655W WO 03037262 A3 WO03037262 A3 WO 03037262A3
Authority
WO
WIPO (PCT)
Prior art keywords
infectives
anit
novel
disclosed
making
Prior art date
Application number
PCT/US2002/034655
Other languages
French (fr)
Other versions
WO2003037262A2 (en
Inventor
Dashyant Dhanak
Kevin J Duffy
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Original Assignee
Smithkline Beecham Corp
Dashyant Dhanak
Kevin J Duffy
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Dashyant Dhanak, Kevin J Duffy, Robert T Sarisky, Antony N Shaw, Rosanna Tedesco filed Critical Smithkline Beecham Corp
Priority to AU2002359320A priority Critical patent/AU2002359320A1/en
Publication of WO2003037262A2 publication Critical patent/WO2003037262A2/en
Publication of WO2003037262A3 publication Critical patent/WO2003037262A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Abstract

Disclosed are compounds useful as HCV anti-infectives and methods of making and using the same.
PCT/US2002/034655 2001-10-29 2002-10-28 Novel anit-infectives WO2003037262A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002359320A AU2002359320A1 (en) 2001-10-29 2002-10-28 Novel anit-infectives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33619001P 2001-10-29 2001-10-29
US60/336,190 2001-10-29

Publications (2)

Publication Number Publication Date
WO2003037262A2 WO2003037262A2 (en) 2003-05-08
WO2003037262A3 true WO2003037262A3 (en) 2003-09-04

Family

ID=23314956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034655 WO2003037262A2 (en) 2001-10-29 2002-10-28 Novel anit-infectives

Country Status (2)

Country Link
AU (1) AU2002359320A1 (en)
WO (1) WO2003037262A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902203B2 (en) 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
NZ549079A (en) 2004-02-20 2010-08-27 Boehringer Ingelheim Int Viral polymerase inhibitors
AU2005276648A1 (en) 2004-08-23 2006-03-02 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
KR100889185B1 (en) 2004-12-21 2009-03-16 에프. 호프만-라 로슈 아게 Tetralin and indane derivatives and uses thereof as 5-ht antagonists
JP2008540370A (en) 2005-05-04 2008-11-20 エフ．ホフマン−ラ ロシュ アーゲー Heterocyclic antiviral compounds
AU2006310612A1 (en) 2005-11-03 2007-05-10 F. Hoffmann-La Roche Ag Arylsulfonylchromans as 5-HT6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
DE602007011213D1 (en) * 2006-02-17 2011-01-27 Hoffmann La Roche HETEROCYCLIC ANTIVIRAL COMPOUNDS
MY145314A (en) 2006-10-10 2012-01-13 Medivir Ab Hcv nucleoside inhibtor
JP5148188B2 (en) * 2007-07-19 2013-02-20 山本化成株式会社 Barbituric acid compounds
TW201035083A (en) 2009-03-06 2010-10-01 Hoffmann La Roche Heterocyclic antiviral compounds
SG175774A1 (en) 2009-04-25 2011-12-29 Hoffmann La Roche Heterocyclic antiviral compounds
MX2011012541A (en) 2009-06-24 2012-08-03 Hoffmann La Roche Heterocyclic antiviral compound.
JP2013505218A (en) 2009-09-21 2013-02-14 エフ．ホフマン−ラ ロシュ アーゲー Heterocyclic antiviral compounds
CN102713630A (en) 2009-11-14 2012-10-03 弗·哈夫曼-拉罗切有限公司 Biomarkers for predicting rapid response to HCV treatment
CA2778206A1 (en) 2009-11-21 2011-05-26 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
SG181104A1 (en) 2009-12-02 2012-07-30 Hoffmann La Roche Biomarkers for predicting sustained response to hcv treatment
RU2534613C2 (en) 2013-03-22 2014-11-27 Александр Васильевич Иващенко Alkyl2-{[(2r,3s,5r)-5-(4-amino-2-oxo-2h-pyrimidine-1-yl)- -hydroxy- tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino}-proptonates, nucleoside inhibitors of rna-polymerase hcv ns5b, methods for producing and using them

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025508A (en) * 1973-08-06 1977-05-24 Serdex - Societe D'etudes, De Recherches, De Diffusion Et D'exploitation 6-(Trifluoromethyl)-benzothiadiazines
US4029780A (en) * 1974-10-29 1977-06-14 Dainippon Pharmaceutical Co., Ltd. 3-Piperazinyl 1,2,4-benzothiadiazine 1,1-dioxide derivatives their compositions and method of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025508A (en) * 1973-08-06 1977-05-24 Serdex - Societe D'etudes, De Recherches, De Diffusion Et D'exploitation 6-(Trifluoromethyl)-benzothiadiazines
US4029780A (en) * 1974-10-29 1977-06-14 Dainippon Pharmaceutical Co., Ltd. 3-Piperazinyl 1,2,4-benzothiadiazine 1,1-dioxide derivatives their compositions and method of use

Also Published As

Publication number Publication date
WO2003037262A2 (en) 2003-05-08
AU2002359320A1 (en) 2003-05-12

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