WO2003059356A3 - Novel anti-infectives - Google Patents

Novel anti-infectives Download PDF

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Publication number
WO2003059356A3
WO2003059356A3 PCT/US2002/034591 US0234591W WO03059356A3 WO 2003059356 A3 WO2003059356 A3 WO 2003059356A3 US 0234591 W US0234591 W US 0234591W WO 03059356 A3 WO03059356 A3 WO 03059356A3
Authority
WO
WIPO (PCT)
Prior art keywords
infectives
novel anti
disclosed
making
methods
Prior art date
Application number
PCT/US2002/034591
Other languages
French (fr)
Other versions
WO2003059356A2 (en
Inventor
Michael G Darcy
Dashyant Dhanak
Kevin J Duffy
Duke M Fitch
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Michael N Zimmerman
Original Assignee
Smithkline Beecham Corp
Michael G Darcy
Dashyant Dhanak
Kevin J Duffy
Duke M Fitch
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Michael N Zimmerman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Michael G Darcy, Dashyant Dhanak, Kevin J Duffy, Duke M Fitch, Robert T Sarisky, Antony N Shaw, Rosanna Tedesco, Michael N Zimmerman filed Critical Smithkline Beecham Corp
Priority to AU2002365198A priority Critical patent/AU2002365198A1/en
Publication of WO2003059356A2 publication Critical patent/WO2003059356A2/en
Publication of WO2003059356A3 publication Critical patent/WO2003059356A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Disclosed are compounds useful as HCV anti-infectives and methods of making and using the same.
PCT/US2002/034591 2001-10-30 2002-10-28 Novel anti-infectives WO2003059356A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002365198A AU2002365198A1 (en) 2001-10-30 2002-10-28 Novel anti-infectives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33854201P 2001-10-30 2001-10-30
US60/338,542 2001-10-30

Publications (2)

Publication Number Publication Date
WO2003059356A2 WO2003059356A2 (en) 2003-07-24
WO2003059356A3 true WO2003059356A3 (en) 2004-01-22

Family

ID=23325196

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034591 WO2003059356A2 (en) 2001-10-30 2002-10-28 Novel anti-infectives

Country Status (2)

Country Link
AU (1) AU2002365198A1 (en)
WO (1) WO2003059356A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4738172B2 (en) * 2002-11-01 2011-08-03 アボット・ラボラトリーズ Antiinfectives
US7902203B2 (en) 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
EP2361913A1 (en) * 2002-11-01 2011-08-31 Abbott Laboratories Anti-infective agents
CN103304541A (en) 2004-02-20 2013-09-18 贝林格尔.英格海姆国际有限公司 Viral polymerase inhibitors
SG137868A1 (en) * 2004-08-23 2007-12-28 Hoffmann La Roche Heterocyclic antiviral compounds
AP2007004040A0 (en) 2004-12-17 2007-06-30 Anadys Pharmaceuticals Inc Pyridazinone compounds
ATE409179T1 (en) 2004-12-21 2008-10-15 Hoffmann La Roche TETRALIN AND INDANDE DERIVATIVES AND THEIR APPLICATIONS AS 5-HT ANTAGONISTS
BRPI0611388A2 (en) 2005-05-04 2010-09-08 Hoffmann La Roche heterocyclic antiviral compounds, their use and pharmaceutical composition
AU2007263084A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Tetralin and indane derivatives and uses thereof
EP2041079A1 (en) 2006-06-20 2009-04-01 F. Hoffmann-Roche AG Arylsulfonyl naphthalene derivatives and uses thereof
WO2007147762A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Arylsulfonamidyl tetralin derivatives and uses thereof
WO2007150001A1 (en) * 2006-06-22 2007-12-27 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
WO2008011337A1 (en) 2006-07-19 2008-01-24 Abbott Laboratories Hcv inhibitors
KR20090078347A (en) 2006-10-10 2009-07-17 메디비르 아베 Hcv nucleoside inhibitor
WO2008073987A1 (en) * 2006-12-12 2008-06-19 Anadys Pharmaceuticals, Inc. Saturated fused [1,2-b] pyridazinone compounds
TW200840572A (en) 2006-12-12 2008-10-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
UA100120C2 (en) 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
US7834009B2 (en) 2007-08-27 2010-11-16 Anadys Pharmaceuticals, Inc. 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds
GB0800855D0 (en) * 2008-01-17 2008-02-27 Syngenta Ltd Herbicidal compounds
WO2009152166A1 (en) 2008-06-10 2009-12-17 Anadys Pharmaceuticals, Inc. [1,2,4]thiadiazine 1,1-dioxide compounds
TW201026675A (en) 2008-10-09 2010-07-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
ES2435799T3 (en) 2008-10-09 2013-12-23 Anadys Pharmaceuticals, Inc. A method of inhibiting hepatitis C virus by combining a 5,6-dihydro-1H-pyridin-2-one and one or more additional antiviral compounds
CN102203091B (en) * 2008-10-29 2014-08-13 巴斯夫欧洲公司 Substituted pyridines having a herbicidal effect
WO2010100178A1 (en) 2009-03-06 2010-09-10 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
AU2010240888A1 (en) 2009-04-25 2011-11-17 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
JP2012527420A (en) * 2009-05-20 2012-11-08 エフ．ホフマン−ラ ロシュ アーゲー Antiviral heterocyclic compounds
SG176976A1 (en) 2009-06-24 2012-02-28 Hoffmann La Roche Heterocyclic antiviral compound
WO2011033045A1 (en) 2009-09-21 2011-03-24 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
EP2493476A4 (en) 2009-10-28 2013-06-19 Anadys Pharmaceuticals Inc Deuterated 5,6-dihydro-1h-pyridin-2-one compounds
BR112012012085A2 (en) 2009-11-21 2016-05-17 Hoffmann La Roche heterocyclic antiviral compounds
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
WO2021030278A1 (en) * 2019-08-12 2021-02-18 Aligos Therapeutics, Inc. Bicyclic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMISTRY OF HETEROCYCLIC COMPOUNDS (NEW YORK), vol. 36, no. 3, 2000, pages 346 - 350 *
DATABASE CAPLUS [online] UKRAINETS ET AL.: "4-Hydroxy-2-quinolones. Part 42. Synthesis and biological activity of 1-substituted 2-oxo-3-(2H-1,2,4-benzothiadiazine-1,1-dioxid-3-yl)-4-Hydroxyquinolines", XP002956156, accession no. STN Database accession no. 2000:335217 *

Also Published As

Publication number Publication date
AU2002365198A1 (en) 2003-07-30
WO2003059356A2 (en) 2003-07-24

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