WO2003020258A1 - Medicament contre la grippe de type a - Google Patents
Medicament contre la grippe de type a Download PDFInfo
- Publication number
- WO2003020258A1 WO2003020258A1 PCT/JP2002/008940 JP0208940W WO03020258A1 WO 2003020258 A1 WO2003020258 A1 WO 2003020258A1 JP 0208940 W JP0208940 W JP 0208940W WO 03020258 A1 WO03020258 A1 WO 03020258A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- airway
- influenza
- drugs
- influenza virus
- secretion
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 5
- 239000003814 drug Substances 0.000 title abstract 5
- 206010022000 influenza Diseases 0.000 title abstract 5
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 230000028327 secretion Effects 0.000 abstract 3
- 241000712461 unidentified influenza virus Species 0.000 abstract 3
- 230000001737 promoting effect Effects 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- JBDGDEWWOUBZPM-XYPYZODXSA-N ambroxol Chemical compound NC1=C(Br)C=C(Br)C=C1CN[C@@H]1CC[C@@H](O)CC1 JBDGDEWWOUBZPM-XYPYZODXSA-N 0.000 abstract 1
- 229960005174 ambroxol Drugs 0.000 abstract 1
- 229960003870 bromhexine Drugs 0.000 abstract 1
- OJGDCBLYJGHCIH-UHFFFAOYSA-N bromhexine Chemical compound C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N OJGDCBLYJGHCIH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0402299A HUP0402299A3 (en) | 2001-09-04 | 2002-09-03 | Anti-influenza drugs containing ambroxol and bromhexine and process for its preparation |
MXPA04002066A MXPA04002066A (es) | 2001-09-04 | 2002-09-03 | Farmacos contra influenza. |
IL16053902A IL160539A0 (en) | 2001-09-04 | 2002-09-03 | Anti-influenzal agents |
CA002459492A CA2459492A1 (en) | 2001-09-04 | 2002-09-03 | Anti-influenzal agent |
KR10-2004-7003276A KR20040045429A (ko) | 2001-09-04 | 2002-09-03 | 항인플루엔자 약제 |
NZ532019A NZ532019A (en) | 2001-09-04 | 2002-09-03 | Anti-influenza drugs |
EP02762982A EP1437134A4 (en) | 2001-09-04 | 2002-09-03 | FLU RESOURCES |
BR0212232-4A BR0212232A (pt) | 2001-09-04 | 2002-09-03 | Agente antiinfluenza |
US10/790,448 US20040242700A1 (en) | 2001-09-04 | 2004-02-27 | Anti-influenzal agent |
HK05101866A HK1069526A1 (en) | 2001-09-04 | 2005-03-03 | Anti-influenza drugs |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001267236 | 2001-09-04 | ||
JP2001-267236 | 2001-09-04 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/790,448 Continuation US20040242700A1 (en) | 2001-09-04 | 2004-02-27 | Anti-influenzal agent |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003020258A1 true WO2003020258A1 (fr) | 2003-03-13 |
Family
ID=19093396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/008940 WO2003020258A1 (fr) | 2001-09-04 | 2002-09-03 | Medicament contre la grippe de type a |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040242700A1 (ja) |
EP (1) | EP1437134A4 (ja) |
KR (1) | KR20040045429A (ja) |
CN (1) | CN1267091C (ja) |
BR (1) | BR0212232A (ja) |
CA (1) | CA2459492A1 (ja) |
HK (1) | HK1069526A1 (ja) |
HU (1) | HUP0402299A3 (ja) |
IL (1) | IL160539A0 (ja) |
MX (1) | MXPA04002066A (ja) |
NZ (1) | NZ532019A (ja) |
WO (1) | WO2003020258A1 (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030166732A1 (en) * | 2002-02-27 | 2003-09-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity |
ITMI20032463A1 (it) * | 2003-12-16 | 2005-06-17 | Advance Holdings Ltd | Soluzione acquosa concentrata a base di ambroxolo |
BRPI0614887A2 (pt) * | 2005-08-25 | 2011-04-19 | Boehringer Ingelheim Int | uso de ambroxol para o tratamento de infecções por rinovìrus |
WO2008123102A1 (ja) * | 2007-03-19 | 2008-10-16 | Yuuzou Tsuchida | 抗ウイルス剤 |
JP5337405B2 (ja) * | 2007-09-17 | 2013-11-06 | ザ・ホスピタル・フォー・シック・チルドレン | ゴーシェ病の治療方法 |
US11583543B2 (en) | 2017-07-16 | 2023-02-21 | Neuere, Llc | Ambroxol to improve and/or extend healthspan, lifespan and/or mental acuity |
WO2019147931A1 (en) | 2018-01-26 | 2019-08-01 | Neuere, Llc | Use of ambroxol to improve skin barrier function |
US20220331408A1 (en) | 2019-07-09 | 2022-10-20 | Genethon | Treatment of glycogen storage disease (gsd) |
WO2021255129A1 (en) * | 2020-06-16 | 2021-12-23 | Spedding Research Solutions, Sas | Novel use of a modulator of glucosylceramide degradation for viral infections |
CN118660866A (zh) | 2021-10-28 | 2024-09-17 | 启威公司 | 治疗用改良型氨溴索 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994008551A2 (en) * | 1992-10-09 | 1994-04-28 | The Procter & Gamble Company | Pharmaceutical compositions and methods for treating cold symptoms |
WO1994014476A1 (en) * | 1992-12-21 | 1994-07-07 | The Procter & Gamble Company | Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders |
JPH06287144A (ja) * | 1993-02-03 | 1994-10-11 | Takeda Chem Ind Ltd | かぜ薬製剤 |
WO1995007103A1 (en) * | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3610997A1 (de) * | 1986-04-02 | 1987-10-15 | Krewel Werke Gmbh | Ambroxol-nasenspray |
EP0841947A1 (en) * | 1995-07-28 | 1998-05-20 | The Procter & Gamble Company | Compositions containing analgesics and antihistamines and methods for treating respiratory disorders |
US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
US5885594A (en) * | 1997-03-27 | 1999-03-23 | The Procter & Gamble Company | Oral compositions having enhanced mouth-feel |
-
2002
- 2002-09-03 IL IL16053902A patent/IL160539A0/xx unknown
- 2002-09-03 MX MXPA04002066A patent/MXPA04002066A/es not_active Application Discontinuation
- 2002-09-03 WO PCT/JP2002/008940 patent/WO2003020258A1/ja active Search and Examination
- 2002-09-03 NZ NZ532019A patent/NZ532019A/en unknown
- 2002-09-03 CN CNB028170601A patent/CN1267091C/zh not_active Expired - Fee Related
- 2002-09-03 KR KR10-2004-7003276A patent/KR20040045429A/ko active Search and Examination
- 2002-09-03 BR BR0212232-4A patent/BR0212232A/pt not_active IP Right Cessation
- 2002-09-03 HU HU0402299A patent/HUP0402299A3/hu unknown
- 2002-09-03 CA CA002459492A patent/CA2459492A1/en not_active Abandoned
- 2002-09-03 EP EP02762982A patent/EP1437134A4/en not_active Withdrawn
-
2004
- 2004-02-27 US US10/790,448 patent/US20040242700A1/en not_active Abandoned
-
2005
- 2005-03-03 HK HK05101866A patent/HK1069526A1/xx not_active IP Right Cessation
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994008551A2 (en) * | 1992-10-09 | 1994-04-28 | The Procter & Gamble Company | Pharmaceutical compositions and methods for treating cold symptoms |
WO1994014476A1 (en) * | 1992-12-21 | 1994-07-07 | The Procter & Gamble Company | Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders |
JPH06287144A (ja) * | 1993-02-03 | 1994-10-11 | Takeda Chem Ind Ltd | かぜ薬製剤 |
WO1995007103A1 (en) * | 1993-09-07 | 1995-03-16 | The Procter & Gamble Company | Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive |
Non-Patent Citations (5)
Title |
---|
DATABASE CAPLUS [online] NISHIKAWA M. ET AL.: "Ambroxol suppresses influenza virus multiplication in the airway by increasing antiviral factor levels", XP002961052, accession no. STN Database accession no. 2002:542180 * |
DATABASE CAPLUS [online] YANG B. ET AL.: "Ambroxol suppresses influenza-virus proliferation in the mouse airway by increasing antiviral factor levels", XP002961053, accession no. STN Database accession no. 2002:444958 * |
EUROPEAN RESPIRATORY JOURNAL, vol. 19, no. 5, 2002, pages 952 - 958 * |
See also references of EP1437134A4 * |
TOKUSHIMA IGAKKAI, vol. 58, no. 3, 2002, pages 162 - 167 * |
Also Published As
Publication number | Publication date |
---|---|
US20040242700A1 (en) | 2004-12-02 |
EP1437134A1 (en) | 2004-07-14 |
BR0212232A (pt) | 2004-10-05 |
CA2459492A1 (en) | 2003-03-13 |
CN1549708A (zh) | 2004-11-24 |
KR20040045429A (ko) | 2004-06-01 |
IL160539A0 (en) | 2004-07-25 |
EP1437134A4 (en) | 2009-03-11 |
MXPA04002066A (es) | 2005-02-17 |
NZ532019A (en) | 2007-04-27 |
HK1069526A1 (en) | 2005-05-27 |
CN1267091C (zh) | 2006-08-02 |
HUP0402299A3 (en) | 2008-04-28 |
HUP0402299A2 (hu) | 2005-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60013836D1 (de) | Replikationsinhibitoren des respiratorischen synzytialvirus | |
AU2002346973A1 (en) | Oral Dosage Form for Propiverine or its Pharmaceutically Acceptable Salts with an Extended Release of the Active Ingredient | |
HK1067310A1 (en) | Oral dosage forms for propiverine or its pharmaceutically acceptable salts with an extended release of the active ingredient | |
NO20016369L (no) | Respiratorisk syncytialvirus-replikasjonsinhibitorer | |
WO2003020258A1 (fr) | Medicament contre la grippe de type a | |
BR0112756A (pt) | Composto, composição farmacêutica, métodos para o tratamento de doenças mediadas por prostaglandina, de congestão nasal, asma alérgica, e rinite alérgica, e, uso de um composto | |
BR0307050A (pt) | Composto, composição farmacêutica, métodos para o tratamento de doenças mediadas por prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, sal farmaceuticamente aceitável, e, uso de um composto ou sal | |
BRPI0517227B8 (pt) | comprimido oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, uso do comprimido | |
NO20016370L (no) | Respiratorisk syncytialvirus-replikasjonsinhibitorer | |
HK1088217A1 (en) | Preparation of sterile aqueous suspensions comprising micronised crystalline active ingredients for inhalation | |
EA200401227A1 (ru) | Система доставки лекарства с контролируемым высвобождением, включающая правастатин | |
CY1110906T1 (el) | Φαρμακευτικη συνθεση για ρινικη χορηγηση φεντανυλης | |
ATE499939T1 (de) | Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend | |
WO2004085682A3 (de) | Caspase inhibitoren, insbesondere von caspase-3, zur behandlung von influenza | |
ATE240717T1 (de) | Wässrige formulierung zur nasalen verabreichung | |
BRPI0411623A (pt) | forma de dosagem farmacêutica ou dietética, esporopolenina, método para a formação de uma esporopolenina funcionalizada com amina primária ou um outro revestimento de exina, método para a formação de uma esporopolenina funcionalizada com poliamino ou um outro revestimento de exina de um esporo, método para a obtenção de uma esporopolenina funcionalizada com aminoácido ou um outro revestimento de exina de um esporo, esporopolenina funcionalizada ou um outro revestimento de exina de um esporo, forma de dosagem dietética ou flavorizante, método de preenchimento de revestimentos de exina de esporos, uso da forma de dosagem e método de aplicação oral de um ingrediente ativo | |
TW200501935A (en) | Use of resveratrol for preparation of a medicament useful for the treatment of influenza virus infections | |
WO2005051350A3 (en) | Water dispersible tablet | |
WO2007057436A3 (en) | Interferon in influenza | |
HUP0202931A2 (hu) | Egy gyógyszerészetileg hatásos összetétel és a beadására szolgáló készülék | |
DE60105243D1 (de) | Oral anzuwendende tramadolhaltige Teilchen zur einmal täglichen Verabreichung | |
ATE402719T1 (de) | Injiziebare pharmazeutische zusammensetzung enthaltend ethanol zur behandlung von bandscheibenvorfällen | |
RU2004125211A (ru) | Способ профилактики заболеваний птиц | |
ITRM20010365A1 (it) | Dispositivo a sigaretta per la somministrazione per via aerea di sostanze medicinali e non. | |
ECSP992961A (es) | Nuevas composiciones farmaceuticas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS KE KG KP KR KZ LK LR LS LT LU LV MA MD MG MK MW MX MZ NO NZ OM PH PL PT RO SD SE SG SI SK SL TJ TM TN TR TT UA UG US UZ VC VN YU ZA ZM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 160539 Country of ref document: IL |
|
WWE | Wipo information: entry into national phase |
Ref document number: 10790448 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 20028170601 Country of ref document: CN |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/2004/002066 Country of ref document: MX Ref document number: 2459492 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020047003276 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002328415 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 532019 Country of ref document: NZ |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002762982 Country of ref document: EP |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWP | Wipo information: published in national office |
Ref document number: 2002762982 Country of ref document: EP |