WO2003020122A1 - Tonometre sans contact - Google Patents

Tonometre sans contact Download PDF

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Publication number
WO2003020122A1
WO2003020122A1 PCT/CH2002/000456 CH0200456W WO03020122A1 WO 2003020122 A1 WO2003020122 A1 WO 2003020122A1 CH 0200456 W CH0200456 W CH 0200456W WO 03020122 A1 WO03020122 A1 WO 03020122A1
Authority
WO
WIPO (PCT)
Prior art keywords
tonometer
light
beam path
interferometer
fiber
Prior art date
Application number
PCT/CH2002/000456
Other languages
German (de)
English (en)
Inventor
Rudolf WÄLTI
Original Assignee
Haag-Streit Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haag-Streit Ag filed Critical Haag-Streit Ag
Priority to EP02754090A priority Critical patent/EP1420682A1/fr
Priority to JP2003524441A priority patent/JP2005500889A/ja
Publication of WO2003020122A1 publication Critical patent/WO2003020122A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers
    • A61B3/165Non-contacting tonometers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1005Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea

Definitions

  • the invention relates to a tonometer for the contactless determination of the intraocular pressure (also referred to as a "non-contact tonometer").
  • a tonometer for the contactless determination of the intraocular pressure also referred to as a "non-contact tonometer”
  • Non-contact tonometers of the type described in US-A-3,585,849 are widely used for periodic monitoring of intraocular pressure in patients.
  • Such tonometers are provided with an air nozzle which is arranged centrally in front of the cornea of the eye to be examined and which generates an air pulse which causes the cornea to deform in such a way that its front surface changes from its natural convex shape to a concave shape through a planar intermediate shape (applanation) Shape is transformed.
  • the cornea After the end of the air pulse, the cornea returns to the convex shape from the concave via the planar due to the intraocular pressure.
  • the time required for the reshaping of the cornea is a measure of the intraocular pressure. To determine this time or the time until the cornea returns to the planar shape, the reflection of a light beam directed onto the cornea and reflected by it is detected.
  • the accuracy of the intraocular pressure determination carried out in this way depends, among other things, on the precise positioning and alignment of the tonometer in relation to the patient's eye.
  • the tonometer described in US Pat. No. 5,299,573 is provided with an optical system which defines a beam path leading through the air nozzle. With exact positioning, the portion of a light beam emitted along the beam path that is reflected back from the front of the comea has an intensity maximum.
  • WO-A-95/20342 proposes a multifunctional ophthalmological device which functions both as a pachymeter for determining the coma thickness and also Has the function of a tonometer for determining the intraocular pressure.
  • the intraocular pressure is measured in the manner of one of the pneumatic non-contact tono- meters, and the measurement of the corneal thickness is carried out by geometrically mapping the front and back reflections of a light beam passing through the cornea onto CCD cells.
  • DE-A-196 47 1 14 describes a further multifunctional ophthalmological device for the simultaneous determination of the intraocular pressure and the corneal thickness, the corneal thickness being measured here in a laser interferometric manner.
  • the previously known ophthalmological devices for contactless determination of the intraocular pressure are either imprecise because they do not correct the measurement errors caused by different corneal thicknesses, or they have a complex construction and are accordingly bulky and expensive.
  • the object of the invention is to provide an ophthalmic device for the contactless determination of the intraocular pressure, which is comparatively inexpensive and enables a precise determination of the intraocular pressure.
  • a non-contact tonometer with an optical system defining an optical path has a connection device for the optionally releasable connection of a device provided with means for transmitting and receiving light, the connection device being designed such that light radiation emitted by the device connected to the tonometer, is coupled into the beam path of the tonometer.
  • light is not only understood to mean only the visible region of the spectrum of electromagnetic radiation, but rather all regions of the spectrum that are customary for ophthalmic applications.
  • the other visible range adjacent infrared and ultraviolet regions of the spectrum of electromagnetic radiation referred to as light.
  • the tonometer according to the invention is based on a conventional non-contact tonometer. This means that the tonometer according to the invention is a fully functional non-contact tonometer even without a connected additional device and can be used as such. Since such known tonometers are comparatively handy, widespread and correspondingly inexpensive, the tonometer according to the invention also has these advantages. In particular, it is much lighter, easier to handle and easier to use than multifunctional ophthalmic devices of the type described in WO-A-95/20342 or DE-A-196 47 1 14.
  • the tonometer according to the invention also has an optical system defining a beam path for the detection of a light beam reflected by the eye to be examined in order to enable precise positioning and adjustment of the tonometer in front of the eye to be examined.
  • the non-contact tonometer is further provided with a connection device for the optionally detachable connection of an additional device, which is designed to emit and receive light radiation, the connection device being designed such that - when the additional device is on the tonometer is connected - the light radiation emitted by the additional device is coupled into the beam path of the tonometer.
  • the connection device of the tonometer comprises at least optical coupling means which make it possible to couple light radiation from outside the tonometer into the beam path of the tonometer.
  • optical coupling means can include, for example, windows or pinholes in the tonometer housing, which allow the passage of light radiation, and / or beam deflection means, such as beam splitters, mirrors, reflectors, lenses, prisms, etc., which guide the light radiation within the tonometer and couple it into the beam path of the tonometer .
  • the connection device of the tonometer can further comprise mechanical coupling means, which can be an optionally detachable mechanical coupling of the additional device or enable a light transmission device (such as an optical fiber or an adapter) that can be connected to this.
  • An additional device that can be connected to the tonometer can be designed to determine further parameters or measurement parameters of the eye to be examined. If required - i.e. if the measurement of further eye parameters is desirable - the additional device can be connected to the tonometer according to the invention by means of the connection device, after which further eye parameters can be measured in addition to the return time of the cornea (after its e.g. pneumatic deflection). Since, in addition to the return time of the cornea, numerous other eye parameters also have an influence on tonometry, the precision of the tonometer measurement can be improved by measuring and taking them into account when determining the intraocular pressure.
  • the light radiation which is emitted by the additional device connected to the tonometer, is coupled into the beam path of the tonometer, no separate system is required for the adjustment of the additional device in front of the eye to be examined. Rather, the adjustment can be carried out with the aid of the corresponding adjustment system of the tonometer. If necessary, the positioning and / or the fixing of the additional device in front of the patient's eye is advantageously also carried out using the means provided for positioning and / or fixing the tonometer. No separate means or devices for the positioning, adjustment and / or fixation of the additional device in front of the eye to be examined are then required.
  • the connection device of a tonometer preferably comprises a beam splitter which is arranged in the beam path of the tonometer between a light detection unit and a nozzle outlet opening of the tonometer.
  • the light detection unit of the tonometer can comprise, for example, a photodetector and / or an eyepiece.
  • the nozzle outlet of the tonometer must be placed in front of the eye to be examined. Air or another medium is blown out through them in order to generate the air pulse required to deflect the cornea.
  • the beam splitter ensures the coupling of a light beam emitted by the additional device into the beam path of the tonometer and in the opposite beam direction for the coupling out of a light beam from the beam path of the tonometer and the transmission of the decoupled light beam to the additional device.
  • the beam splitter can be permanently installed in the tonometer so that it remains in the beam path of the tonometer even without an additional device connected. Tonometric measurements are still possible, however, in comparison to a beam path without a beam splitter, a weakening of the light beam from the tonometer has to be accepted.
  • the beam splitter can also be arranged removably in the beam path of the tonometer, so that it can be removed from the beam path of the tonometer if no additional device is connected to the tonometer.
  • connection device can, however, also have other suitable means for coupling the light radiation emitted by the additional device into the beam path of the tonometer, such as e.g. Mirrors, reflectors, prisms etc.
  • a tonometer arrangement comprises a non-contact tonometer with an optical system defining a beam path and a connection device for the optionally releasable connection of a device provided with means for transmitting and receiving light, the connection device being designed such that light radiation which is transmitted from the device connected to the tonometer, is coupled into the beam path of the tonometer.
  • the tonometer arrangement further comprises a device provided with means for transmitting and receiving light, which is designed such that it can be connected to the tonometer by means of the connection device of the tonometer in such a way that light radiation emitted by the device connected to the tonometer is in the beam path of the tonometer is coupled.
  • a tonometer arrangement comprises a device set consisting of at least one tonometer and a further device which can optionally be detachably connected to this tonometer.
  • the device of the tonometer arrangement that can be connected to the tonometer is preferably designed such that after the device is connected to the tonometer, the tonometer arrangement for measuring the corneal thickness and / or the comea curvature and / or corneal topography and / or the tear film thickness and / or the comeal epithelium thickness and / or the thickness of a comal flap of an eye to be examined, whereby a comea flap is to be understood as a flap of the cornea which is partially cut away from the cornea in connection with a surgical operation and can be folded forward by it.
  • the precision of the tonometer measurement can be improved by measuring them and taking them into account when determining the intraocular pressure.
  • the pachymeter can be connected to the tonometer according to the invention by means of the connecting device, whereupon In addition to the return time of the cornea (after its pneumatic deflection, for example), the corneal thickness can also be measured and the two measured values can be used to precisely determine the intraocular pressure.
  • devices for measuring eye parameters relevant to tonometry basically other devices suitable for ophthalmological applications can also be connected to the tonometer which are designed to emit light radiation, e.g. Devices for laser surgical treatment of the eye.
  • the device which can be connected to the tonometer comprises an interferometer which is designed for interferometric measurements based on light radiation emitted by the interferometer, coupled into the beam path of the tonometer via the connection device of the tonometer and at least partially through the beam path of the tonometer and the connection device is reflected back to the interferometer.
  • Interferometer of the tonometer arrangement according to this embodiment of the invention is provided with its own means for positioning, aligning, adjusting and / or fixing the interferometer in front of the eye to be examined. The positioning, alignment, adjustment and / or fixation of the interferometer is rather advantageously carried out with the aid of the corresponding systems of the tonometer.
  • the interferometer used as part of the tonometer arrangement according to the invention can be an interferometer based on the interferometric measuring principle of optical short coherence reflectometry (English “optical low coherence reflectrometry” or OLCR).
  • Such interferometers are known from the publications WO-A-01/19303 and WO-A-01/38820. They are suitable for measuring the corneal thickness and the tear film thickness.
  • the interferometer used as part of the tonometer arrangement according to the invention can also be an interferometer based on the interferometric measuring principle of optical short coherence tomography (OCT).
  • OCT optical short coherence tomography
  • Such interferometers are known from WO-A-99/22198 and WO-A-01/19303. They are suitable for measuring coma curvature and corneal topography.
  • the device that can be connected to the tonometer can in principle also include other interferometers suitable for ophthalmic applications.
  • the tonometer arrangement additionally comprises an adapter unit which has at least one lens.
  • the adapter unit is used to optically adapt the device that can be connected to the tonometer to the tonometer.
  • the adapter unit makes it possible to connect a large number of different devices designed to emit light radiation with different optical properties of the emitted light radiation to the tonometer. It is designed such that it can be arranged between the device that can be connected to the tonometer and the tonometer in such a way that a light beam emitted by the device passes through the lens and is then coupled into the beam path of the tonometer.
  • the adapter unit can be designed as a separate unit that can be detached from the tonometer and from the device that can be connected to it, and can be arranged at any suitable point in the light transmission path between the tonometer and the device. As an alternative to this, however, it can also be designed as part of the connection device of the tonometer or as part of the device that can be connected to the tonometer.
  • the adapter unit can be provided with a beam deflection system for controllably deflecting the light beam emitted by the device.
  • a beam deflection system for controllably deflecting the light beam emitted by the device.
  • the beam deflection system comes e.g. one or more movable mirrors, one or more transversely displaceable lenses, and other known beam deflection systems in question.
  • the integration of the beam deflection system into the adapter unit has the advantage that only a single beam deflection and adapter functional unit, which can be used for a large number of different devices, is required to connect and adapt various devices working with deflectable beams to the tonometer. In principle, however, it is also possible to arrange a beam deflection system at any suitable point in the light transmission path between the tonometer and the device, regardless of an adapter unit which may or may not be present.
  • the tonometer arrangement further comprises a fiber connection unit which has at least one light-conducting fiber and is designed such that it can be arranged between the device which can be connected to the tonometer and the tonometer in such a way that that the light radiation emitted by the device is coupled into the beam path of the tonometer after passing through the fiber.
  • a flexible single-mode fiber is preferably used as the light-conducting fiber.
  • the fiber connection unit makes it possible to install the device that can be connected to the tonometer at a fixed location and only to arrange the tonometer on a mechanically movable adjustment and positioning unit (which includes, for example, a cross slide), which provides the positioning, alignment and adjustment of the tonometer required for eye examination with respect to the eye to be examined.
  • connection device of the tonometer or an adapter unit arranged in front of it is designed for light radiation, which is emitted by the connected device in the form of a free-space beam
  • the fiber connection unit can be provided on the tonometer side with an in / out coupler, which couples the light radiation out of the fiber and into it converts a free space beam.
  • the free-space beam coming from the tonometer or from the adapter unit is coupled into the fiber of the fiber connection unit through this coupling-in / coupling-out.
  • the fiber connection unit can be provided on the tonometer side with a fiber connector which transmits light between the light fiber of the fiber connection unit and an optical fiber the connection device of the tonometer.
  • the fiber connection unit can also be provided on the side of the device to be connected to the tonometer with an in / out coupler or a fiber connector, depending on whether this device is designed to emit / receive open space light radiation or light radiation guided in an optical fiber.
  • the fiber connection unit can be designed as a separate unit that can be detached from the tonometer and from the device that can be connected to it, and can be arranged at any suitable point in the light transmission path between the tonometer and the device.
  • it can also be designed as part of the connection device of the tonometer or as part of the device that can be connected to the tonometer.
  • Fig. 1 shows a tonometer arrangement according to a preferred embodiment of the
  • FIG. 2 shows a simplified schematic illustration of a fiber connection unit for the tonometer arrangement from FIG. 1.
  • the tonometer arrangement shown in FIG. 1 comprises a non-contact tonometer 10, a measuring device 70 that can be connected to the tonometer 10, a fiber connection unit 60 and an adapter unit 50.
  • the non-contact tonometer 10 has a piston 1 which is displaceably guided in a cylinder 12. By suddenly moving the piston 14, a pulsating air flow can be blown out through a cylinder opening 16.
  • the air flows through a connecting line 18 into an air chamber 20 and is ejected from there in the form of air pulses through an air nozzle 22 which is arranged centrally in front of the cornea of an eye 2 to be examined.
  • the rear wall of the air chamber 20 opposite the air nozzle 22 is provided with a translucent window 24. This window 24 is part of an optical system for. exact alignment and adjustment of the tonometer 10 in front of the eye 2 to be examined and for determining the applanation of the cornea of the eye 2 caused by the air pulses.
  • the optical system of the tonometer 10 further comprises an objective lens 26, a collimator lens 28 and a first photodetector 30 which are arranged in a straight line behind the window 24.
  • a first beam splitter 34 is arranged between the objective lens 26 and the collimator lens 28 and reflects the light radiation emitted by a light source 36 of the tonometer 10 through the objective lens 26, the window 24 and the air nozzle 22, the light radiation between the light source 36 and the first beam splitter 34 passes through a condenser lens 38.
  • a second beam splitter 40 is arranged between the collimator lens 28 and the first photodetector 30, which reflects part of the light beam to a second photodetector 42, while another part of the light beam passes through the second beam splitter 40 to the first photodetector 30.
  • a beam path 32 is defined by the optical system of the tonometer 10 such that light, which is emitted continuously by the light source 36, passes along the beam path 32 through the condenser lens 38, is reflected by the first beam splitter 34 and by the objective lens 26, the Window 24 and the air nozzle 22 fall through onto the cornea of eye 2. From this, the light radiation is partially reflected back along the beam path 32 through the air nozzle 22, the window 24, the objective lens 26, the first beam splitter 34 and the collimator lens 28 to the second beam splitter 40. Part of this light radiation is reflected by the second beam splitter 40 to the second photodetector 42, another part of the light radiation passes through the second beam splitter 40 and a third beam splitter 44 to the first photodetector 30.
  • a temporal radiation maximum is detected, from which the time is determined which the cornea needs after a deflection by an air pulse until it returns to a planar shape. This time is used to calculate the intraocular pressure.
  • the second photodetector is used to determine a Radiation maximum, which indicates within the scope of the alignment of the tonometer 10 that the light beam emerging through the air nozzle 22 is aligned perpendicular to the corneal surface of the eye 2.
  • the third beam splitter 44 is arranged between the second beam splitter 40 and the first photo detector 30 in the beam path 32 of the tonometer 10.
  • This third beam splitter 44 is part of a connection device for optionally detachable connection of the measuring device 70 which can be connected to the tonometer 10.
  • the connection device of the tonometer 10 further comprises a coupling piece (not shown) attached to the tonometer 10, which is part of a first coupling device (not shown), which further has a counterpart (not shown) corresponding to the coupling piece attached to the tonometer, which is attached to the adapter unit 50.
  • the first coupling device is used for optionally releasably coupling the adapter unit 50 to the tonometer 10 in such a way that in the coupled state, light radiation in the form of a free-space beam can be transmitted from the adapter unit 50 to the tonometer 10 and in the opposite direction.
  • any of those which are common in technical optics, e.g. screwable or only pluggable coupling device can be used.
  • the adapter unit 50 serves to optically adapt the measuring device 70 to the optical system of the tonometer 10 and has two adapter lenses 52, 54 for this purpose.
  • a coupling piece (not shown) is attached to the adapter unit 50, which is part of a second coupling device, which further comprises an on / off coupler 62, which is attached to the end of the fiber connection unit 60 on the tonometer side.
  • the in / out coupler 62 can optionally be releasably coupled to the coupling piece attached to the adapter unit 50 such that, in the coupled state, light radiation in the form of a free space beam can be transmitted from the in / out coupler 62 to the adapter unit 50 and in the opposite direction.
  • the in / out coupler 62 can, for example, only consist of one fiber connector and one with a perforated end piece, which is used only to hold the fiber and let the jet emerge.
  • the fiber connection unit 60 shown in a detailed view in FIG. 2 serves to create a flexible, light-conducting connection between the measuring device 70 and the tonometer 10 or the adapter unit 50 coupled to the tonometer 10.
  • the fiber connection unit 60 includes Furthermore, a flexible, light-guiding monomode fiber 66 and a fiber connector 64.
  • the in / out coupler 62 is attached to the monomode fiber 66 at the end of the tonometer. It couples the light radiation emitted by the measuring device 70 out of the fiber 66 and converts it into a free-space beam, which is introduced into the adapter unit 50.
  • the input / output coupler 62 couples a free-space beam coming from the adapter unit 50 into the single-mode fiber 66.
  • the fiber connector 64 is attached to the end of the single-mode fiber 66 on the measuring device side. It can optionally be releasably connected to a connector counterpart 72 corresponding to the fiber connector 64, which is attached to an optical fiber 74 of the measuring device 70, the optical fiber 74 in turn being a momomode fiber 74.
  • the fiber connector 64 and the connector counterpart 72 create a light-transmitting, fiber-optic connection between the optical fiber 74 of the measuring device 70 and the single-mode fiber 66 of the fiber connection unit 60.
  • the measuring device 70 shown in FIG. 1 comprises a fiber-optic interferometer based on the interferometric measuring principle of optical short-coherent tomography, as described in the publication WO-A-01/19303.
  • the optical fiber 74 provided with the connector counterpart 72 is part of the measuring arm of this interferometer.
  • the measuring device 70 If the measuring device 70 is connected to the tonometer 10 via the fiber connection unit 60 and the adapter unit 50, the measuring device 70 emits light by feeding light radiation into the optical fiber 74. This light radiation is conducted via the connector counterpart 72, the fiber connector 64 and the single-mode fiber 66 to the in / out coupler 62, which couples it out of the single-mode fiber 66 and as a free-space beam passed through the adapter lenses 52, 54 to the third beam splitter 44. From this the light beam is reflected in the direction of the beam path 32 of the tonometer 10 and thereby coupled into this beam path 32.
  • the in / out coupler 62 couples the free-space beam coming from the adapter unit into the single-mode fiber 66, through which the light radiation reflected back by the eye 2 to the fiber connector 64, the connector counterpart 72 and finally into the light fiber 74 and thus into the measuring arm of the fiber-optic interferometer Meter 70 is passed.
  • the light radiation back-reflected by the eye 2 is evaluated interferometrically in the measuring device 70 in order to determine the thickness of the cornea of the eye 2.
  • the measured value for the corneal thickness determined in this way is then used together with the return time of the cornea measured by the tonometer 10 in order to determine the internal pressure of the eye 2.
  • the third beam splitter 44 can also be arranged at other suitable locations in the beam path 32 of the tonometer 10, e.g. between the second beam splitter 40 and the second photodetector 42 or between the first beam splitter 34 and the condenser lens 38 or between the condenser lens 38 and the light source 36.
  • any other device suitable for ophthalmological applications can optionally be detachably connected to the tonometer 10 again.
  • This can be, for example trade any of the devices described in WO-A-01/38820, WO-A-99/22198 and WO-A-01/19303. If such a device does not emit or receive the light as shown in FIG. 1 via an optical fiber 74, but via a free-space beam, a further adapter device 50, which is similar to the adapter device 50 shown in FIG. 1, can be located between the device and a fiber connection unit, which essentially corresponds to the fiber connection unit 60 shown in FIG. 1.
  • the invention specifies an ophthalmic device for the contactless determination of the intraocular pressure, which is comparatively inexpensive and enables a precise determination of the intraocular pressure.

Abstract

L'invention concerne un tonomètre sans contact (10), équipé d'un système optique définissant une trajectoire de rayonnement (32). Ce tonomètre présente une unité de raccordement servant à raccorder, de manière éventuellement libérable, un appareil (70) pourvu de moyens d'émission et de réception de lumière. Cette unité de raccordement est conçue de sorte que le rayonnement lumineux émis par l'appareil (70) raccordé au tonomètre (10) soit injecté dans la trajectoire de rayonnement (32) du tonomètre (10). Ce tonomètre sans contact (10) est relativement peu onéreux et permet une détermination précise de la tension intraoculaire.
PCT/CH2002/000456 2001-08-31 2002-08-22 Tonometre sans contact WO2003020122A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02754090A EP1420682A1 (fr) 2001-08-31 2002-08-22 Tonometre sans contact
JP2003524441A JP2005500889A (ja) 2001-08-31 2002-08-22 非接触式眼圧計

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH16202001 2001-08-31
CH1620/01 2001-08-31

Publications (1)

Publication Number Publication Date
WO2003020122A1 true WO2003020122A1 (fr) 2003-03-13

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PCT/CH2002/000456 WO2003020122A1 (fr) 2001-08-31 2002-08-22 Tonometre sans contact

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EP (1) EP1420682A1 (fr)
JP (1) JP2005500889A (fr)
WO (1) WO2003020122A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3335386A1 (de) * 1983-09-29 1985-04-11 Siemens AG, 1000 Berlin und 8000 München Schaltung zur csd-codierung einer im zweierkomplement dargestellten, binaeren zahl
JP5658018B2 (ja) * 2010-12-10 2015-01-21 株式会社ニデック 眼科検査装置
EP2583620B1 (fr) * 2013-01-24 2017-08-23 Haag-Streit Ag Topographe
FI128150B (en) 2018-11-29 2019-11-15 Photono Oy A system and method for measuring intraocular pressure

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3585849A (en) 1968-10-09 1971-06-22 American Optical Corp Method and apparatus for measuring intraocular pressure
US5299573A (en) 1992-01-08 1994-04-05 Canon Kabushiki Kaisha Tonometer
WO1995020342A1 (fr) 1994-01-31 1995-08-03 Leica Inc. Tonometre sans contact ameliore
DE19647114A1 (de) 1996-11-14 1998-05-28 Univ Ilmenau Tech Verfahren und Vorrichtung zur berührungslosen Messung des Augeninnendruckes
WO1999022198A1 (fr) 1997-10-23 1999-05-06 Ecole Polytechnique Federale De Lausanne Procede et dispositif de mesure des caracteristiques optiques d'objets transparents et/ou diffusants
WO2001019303A1 (fr) 1999-09-10 2001-03-22 Haag-Streit Ag Procede et dispositif de photoablation de la cornee par rayonnement laser
WO2001038820A1 (fr) 1999-11-24 2001-05-31 Haag-Streit Ag Procede et dispositif pour mesurer les proprietes optiques d'au moins deux secteurs distants l'un de l'autre dans un objet transparent et/ou diffusant

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3585849A (en) 1968-10-09 1971-06-22 American Optical Corp Method and apparatus for measuring intraocular pressure
US5299573A (en) 1992-01-08 1994-04-05 Canon Kabushiki Kaisha Tonometer
WO1995020342A1 (fr) 1994-01-31 1995-08-03 Leica Inc. Tonometre sans contact ameliore
DE19647114A1 (de) 1996-11-14 1998-05-28 Univ Ilmenau Tech Verfahren und Vorrichtung zur berührungslosen Messung des Augeninnendruckes
WO1999022198A1 (fr) 1997-10-23 1999-05-06 Ecole Polytechnique Federale De Lausanne Procede et dispositif de mesure des caracteristiques optiques d'objets transparents et/ou diffusants
WO2001019303A1 (fr) 1999-09-10 2001-03-22 Haag-Streit Ag Procede et dispositif de photoablation de la cornee par rayonnement laser
WO2001038820A1 (fr) 1999-11-24 2001-05-31 Haag-Streit Ag Procede et dispositif pour mesurer les proprietes optiques d'au moins deux secteurs distants l'un de l'autre dans un objet transparent et/ou diffusant

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JP2005500889A (ja) 2005-01-13

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