WO2003018775A3 - Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays - Google Patents

Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays Download PDF

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Publication number
WO2003018775A3
WO2003018775A3 PCT/US2002/028471 US0228471W WO03018775A3 WO 2003018775 A3 WO2003018775 A3 WO 2003018775A3 US 0228471 W US0228471 W US 0228471W WO 03018775 A3 WO03018775 A3 WO 03018775A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplogroups
associations
physiological conditions
mitochondrial dna
human mitochondrial
Prior art date
Application number
PCT/US2002/028471
Other languages
French (fr)
Other versions
WO2003018775A2 (en
Inventor
Douglas C Wallace
Seyed Hosseini
Dan Mishmar
Eduardo Ruiz-Pesini
Marie Lott
Original Assignee
Univ Emory
Douglas C Wallace
Seyed Hosseini
Dan Mishmar
Eduardo Ruiz-Pesini
Marie Lott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2356536 external-priority patent/CA2356536A1/en
Application filed by Univ Emory, Douglas C Wallace, Seyed Hosseini, Dan Mishmar, Eduardo Ruiz-Pesini, Marie Lott filed Critical Univ Emory
Priority to US10/488,618 priority Critical patent/US20050123913A1/en
Priority to CA002459127A priority patent/CA2459127A1/en
Priority to EP02796465A priority patent/EP1432831A4/en
Priority to JP2003523626A priority patent/JP2005525082A/en
Publication of WO2003018775A2 publication Critical patent/WO2003018775A2/en
Publication of WO2003018775A3 publication Critical patent/WO2003018775A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

This inention provides human mtDNA polymorphisms that are diagnostic of all the major human haplogroups and methods of diagnosing those haplogroups and selected haplogroups.
PCT/US2002/028471 2001-08-30 2002-08-30 Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays WO2003018775A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US10/488,618 US20050123913A1 (en) 2001-08-30 2002-08-30 Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays
CA002459127A CA2459127A1 (en) 2001-08-30 2002-08-30 Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays
EP02796465A EP1432831A4 (en) 2001-08-30 2002-08-30 Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays
JP2003523626A JP2005525082A (en) 2001-08-30 2002-08-30 Human mitochondrial DNA polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US31633301P 2001-08-30 2001-08-30
US60/316,333 2001-08-30
CA2,356,536 2001-08-31
CA 2356536 CA2356536A1 (en) 2001-08-30 2001-08-31 Mitochondrial dna sequence alleles
US38054602P 2002-05-13 2002-05-13
US60/380,546 2002-05-13

Publications (2)

Publication Number Publication Date
WO2003018775A2 WO2003018775A2 (en) 2003-03-06
WO2003018775A3 true WO2003018775A3 (en) 2003-10-23

Family

ID=27171588

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/028471 WO2003018775A2 (en) 2001-08-30 2002-08-30 Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays

Country Status (3)

Country Link
EP (1) EP1432831A4 (en)
JP (1) JP2005525082A (en)
WO (1) WO2003018775A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5360854B2 (en) * 2006-06-14 2013-12-04 雅嗣 田中 Gene detection method for type 2 diabetes
JP5276257B2 (en) * 2006-06-14 2013-08-28 雅嗣 田中 Gene detection method for human mitochondrial DNA
JP5360855B2 (en) * 2006-06-14 2013-12-04 雅嗣 田中 Gene detection method for myocardial infarction
JP5360853B2 (en) * 2006-06-14 2013-12-04 雅嗣 田中 Gene detection method for metabolic syndrome
JP5396586B2 (en) * 2006-06-14 2014-01-22 雅嗣 田中 Gene detection method for atherothrombotic cerebral infarction
KR100892253B1 (en) * 2006-09-07 2009-04-10 (주)지노첵 Method, Polynucleotide Probe, DNA Chip and Kit for Identifying Mutation of Human Mitochondrial DNA
CN103290109B (en) * 2013-04-17 2015-01-28 浙江大学 Kit for detecting mitochondrial T4353C mutation linked to hypertension and application thereof
EP3091083B1 (en) * 2015-05-07 2017-11-08 Latvian Biomedical Research and Study Centre A kit for detecting mutation or polymorphism in the human mitochondrial dna

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837832A (en) * 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976798A (en) * 1994-03-30 1999-11-02 Mitokor Methods for detecting mitochondrial mutations diagnostic for Alzheimer's disease and methods for determining heteroplasmy of mitochondrial nucleic acid

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837832A (en) * 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANDREWS ET AL.: "Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA", NATURE GENETICS, vol. 23, October 1999 (1999-10-01), pages 147, XP002961687 *
DATABASE GENBANK [online] CENTER FOR BIOTECHNOLOGY INFORMATION, NATIONAL LIBRARY OF MEDICINE, NIH (BETHESDA, MD, USA); 18 April 2000 (2000-04-18), CREWS S. ET AL., XP002108769, accession no. NCBI Database accession no. (J01415) *
NATURE, vol. 277, no. 5693, 1979, pages 192 - 198 *
See also references of EP1432831A4 *

Also Published As

Publication number Publication date
WO2003018775A2 (en) 2003-03-06
EP1432831A2 (en) 2004-06-30
EP1432831A4 (en) 2006-06-14
JP2005525082A (en) 2005-08-25

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