WO2003013598A3 - Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases - Google Patents
Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases Download PDFInfo
- Publication number
- WO2003013598A3 WO2003013598A3 PCT/US2002/025126 US0225126W WO03013598A3 WO 2003013598 A3 WO2003013598 A3 WO 2003013598A3 US 0225126 W US0225126 W US 0225126W WO 03013598 A3 WO03013598 A3 WO 03013598A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- vaccine
- bacteria
- plant
- veterinary
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/20011—Coronaviridae
- C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31110601P | 2001-08-09 | 2001-08-09 | |
US60/311,106 | 2001-08-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003013598A2 WO2003013598A2 (en) | 2003-02-20 |
WO2003013598A3 true WO2003013598A3 (en) | 2004-01-08 |
Family
ID=23205432
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/025126 WO2003013598A2 (en) | 2001-08-09 | 2002-08-08 | Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2003013598A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9220737B2 (en) | 2003-04-27 | 2015-12-29 | Protalix Ltd. | Plant cell culture expressing human lysosomal proteins and uses thereof |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL201420B1 (en) * | 2002-12-04 | 2009-04-30 | Inst Biotechnologii I Antybiot | Chimeric protein, sequence, construction, vegetable cell, method of obtaining chimeric protein and transgenic plant, application of transgenic plant and chimeric protein |
PL199190B1 (en) * | 2002-12-31 | 2008-08-29 | Inst Biotechnologii I Antybiot | Inclusion bodies as antigenes in nutritional immunization of animals |
KR20070085291A (en) | 2004-10-13 | 2007-08-27 | 프로탈릭스 리미티드 | System and method for production of antibodies in plant cell culture |
WO2007010533A2 (en) * | 2005-07-18 | 2007-01-25 | Protalix Ltd. | Mucosal or enteral administration of biologically active macromolecules |
EP3366762B1 (en) | 2007-05-07 | 2020-07-08 | Protalix Ltd. | Large scale disposable bioreactor |
ES2733525T3 (en) * | 2012-07-13 | 2019-11-29 | Univ Pennsylvania | Methods to assess the adequacy of transduced T lymphocytes for administration |
US20140096285A1 (en) * | 2012-10-02 | 2014-04-03 | The Board Of Trustees Of The University Of Illinois | Soybean-based porcine reproductive and respiratory syndrome virus vaccine and methods for making and using the same |
SG10201913782UA (en) | 2014-07-21 | 2020-03-30 | Novartis Ag | Treatment of cancer using a cll-1 chimeric antigen receptor |
MY181834A (en) | 2014-07-21 | 2021-01-08 | Novartis Ag | Treatment of cancer using humanized anti-bcma chimeric antigen receptor |
JP7438988B2 (en) | 2018-06-13 | 2024-02-27 | ノバルティス アーゲー | BCMA chimeric antigen receptor and its use |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994020135A1 (en) * | 1993-03-04 | 1994-09-15 | Edible Vaccines Inc. | Vaccines expressed in plants |
WO1999008706A1 (en) * | 1997-08-14 | 1999-02-25 | Commonwealth Scientific And Industrial Research Organisation | Recombinant porcine adenovirus vector |
EP1293573A2 (en) * | 2001-09-18 | 2003-03-19 | Maltagen Forschung GmbH | Process for producing a marker-vaccine against a mammalian virus |
-
2002
- 2002-08-08 WO PCT/US2002/025126 patent/WO2003013598A2/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994020135A1 (en) * | 1993-03-04 | 1994-09-15 | Edible Vaccines Inc. | Vaccines expressed in plants |
WO1999008706A1 (en) * | 1997-08-14 | 1999-02-25 | Commonwealth Scientific And Industrial Research Organisation | Recombinant porcine adenovirus vector |
EP1293573A2 (en) * | 2001-09-18 | 2003-03-19 | Maltagen Forschung GmbH | Process for producing a marker-vaccine against a mammalian virus |
Non-Patent Citations (11)
Title |
---|
CHAN CAROL W M ET AL: "Expression of Hog Cholera Virus E2 in transgenic Arabidopsis.", PLANT BIOLOGY (ROCKVILLE), vol. 2002, 2002, Annual Meeting of the American Society of Plant Biologists on Plant Biology;Denver, CO, USA; August 03-07, 2002, 2002, pages 57, XP002250044 * |
DANIELL H ET AL: "MEDICAL MOLECULAR FARMING: PRODUCTION OF ANTIBODIES, BIOPHARMACEUTICALS AND EDIBLE VACCINES IN PLANTS", TRENDS IN PLANT SCIENCE, ELSEVIER SCIENCE, OXFORD, GB, vol. 6, no. 5, May 2001 (2001-05-01), pages 219 - 226, XP001037864, ISSN: 1360-1385 * |
HULST M M ET AL: "Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera", JOURNAL OF VIROLOGY, NEW YORK, US, US, vol. 67, no. 9, 1 September 1993 (1993-09-01), pages 5435 - 5442, XP002080070, ISSN: 0022-538X * |
KIM HYUNSOON ET AL: "Expression of hog cholera virus in transgenic potato plants.", PLANT BIOLOGY (ROCKVILLE), vol. 2001, 2001, Joint Annual Meetings of the American Society of Plant Biologists and the Canadian Society of Plant Physiologists;Providence, Rhode Island, USA; July 21-25, 2001, pages 142, XP001161300 * |
LAFAYETTE PETER R ET AL: "Engineering soybeans for the production of edible vaccines for poultry.", PLANT BIOLOGY (ROCKVILLE), vol. 2000, 2000, Annual Meeting of the American Society of Plant Physiologists;San Diego, California, USA; July 15-19, 2000, pages 138, XP002250043 * |
PLANA DURAN ET AL: "Baculovirus expression of proteins of Reproductive and Respiratory Syndrome Virus strain Olot/91. Involvement of ORF3 and ORF5 proteins in protection", VIRUS GENES, KLUWER ACADEMIC PUBLISHERS, BOSTON, US, vol. 14, no. 1, 1997, pages 19 - 29, XP002103647, ISSN: 0920-8569 * |
STREATFIELD S J ET AL: "Plant-based vaccines: unique advantages", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 19, no. 17-19, 21 March 2001 (2001-03-21), pages 2742 - 2748, XP004231106, ISSN: 0264-410X * |
TUBOLY T ET AL: "Immunogenicity of porcine transmissible gastroenteritis virus spike protein expressed in plants", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 18, no. 19, April 2000 (2000-04-01), pages 2023 - 2028, XP004202498, ISSN: 0264-410X * |
VAN GENNIP A H G P ET AL: "Chimeric classical swine fever viruses containing envelope protein E or E2 of bovine viral diarrhoea virus protect pigs against challenge with CSFV and induce a distinguishable antibody response", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 19, no. 4-5, 15 October 2000 (2000-10-15), pages 447 - 459, XP004218115, ISSN: 0264-410X * |
VAN RIJN P A ET AL: "An experimental marker vaccine and accompanying serological diagnostic test both based on envelope glycoprotein E2 of classical swine fever virus (CSFV)", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 17, no. 5, February 1999 (1999-02-01), pages 433 - 440, XP004153825, ISSN: 0264-410X * |
WIGDOROVITZ A ET AL: "Induction of a Protective Antibody Response to Foot and Mouth Disease Virus in Mice Following Oral or Parenteral Immunization with Alfalfa Transgenic Plants Expressing the Viral Structural Protein VP1", VIROLOGY, ACADEMIC PRESS,ORLANDO, US, vol. 255, no. 2, 15 March 1999 (1999-03-15), pages 347 - 353, XP004440022, ISSN: 0042-6822 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9220737B2 (en) | 2003-04-27 | 2015-12-29 | Protalix Ltd. | Plant cell culture expressing human lysosomal proteins and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2003013598A2 (en) | 2003-02-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2446208C2 (en) | Application and method for preventing and treating caries caused by mutans streptococci different from streptococcus mutans | |
US20200085727A1 (en) | Means and methods for preventing and/or treating caries | |
CN104277998B (en) | Use and method for preventing and/or treating oral malodor | |
WO2003013598A3 (en) | Novel vaccine compositions and methods of vaccine preparation for veterinary and human diseases | |
HK1076642A1 (en) | Recombinant poxvirus expressing homologous genes inserted into the poxviral genome | |
WO2003029401A3 (en) | Peptidoglycan recognition protein encoding nucleic acids and methods of use thereof | |
JP6755801B2 (en) | Therapeutic phage and methods for nucleic acid delivery for therapeutic use | |
WO2004037175A3 (en) | Compositions and methods for treating human papillomavirus-mediated disease | |
RU2002112327A (en) | LANTIBIOTIC | |
TW200407426A (en) | Vaccines | |
KR102530966B1 (en) | Periodontitis vaccine and related compositions and methods of use | |
TW202310869A (en) | Composition comprising superoxide dismutase and/or bacillus strain spores, and uses thereof for improving oral health | |
CN102772792B (en) | Vaccine for preventing decayed tooth and preparation method thereof | |
KR20140130944A (en) | Live vaccine composition comprising attenuated Salmonella mutants for preventing progressive atrophic rhinitis and pneumonic pastuellosis | |
TWI434852B (en) | Peptide for modulating the immune responses of osteichthyes and applications in relative to the same | |
TW202320829A (en) | Combined use for improving oral health of aucuba japonica extracts and compositions comprising superoxide dismutase and/or bacillus strain spores | |
Lam et al. | Vaccines expressed in plants |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VC VN YU ZA ZM |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Country of ref document: JP |