WO2002092606A8 - Derives d'imidazolidine fusionnes, leur procede de preparation et d'utilisation - Google Patents
Derives d'imidazolidine fusionnes, leur procede de preparation et d'utilisationInfo
- Publication number
- WO2002092606A8 WO2002092606A8 PCT/JP2002/004640 JP0204640W WO02092606A8 WO 2002092606 A8 WO2002092606 A8 WO 2002092606A8 JP 0204640 W JP0204640 W JP 0204640W WO 02092606 A8 WO02092606 A8 WO 02092606A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- same
- optionally substituted
- fused
- preparation
- substituted hydrocarbyl
- Prior art date
Links
- 150000002461 imidazolidines Chemical class 0.000 title 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 102000055008 Matrilin Proteins Human genes 0.000 abstract 1
- 108010072582 Matrilin Proteins Proteins 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001144608 | 2001-05-15 | ||
JP2001-144608 | 2001-05-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002092606A1 WO2002092606A1 (fr) | 2002-11-21 |
WO2002092606A8 true WO2002092606A8 (fr) | 2002-12-19 |
Family
ID=18990527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/004640 WO2002092606A1 (fr) | 2001-05-15 | 2002-05-14 | Derives d'imidazolidine fusionnes, leur procede de preparation et d'utilisation |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2002092606A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004069999A2 (fr) * | 2003-02-04 | 2004-08-19 | Takeda Pharmaceutical Company Limited | Procede de criblage |
ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
ES2320961B1 (es) | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
US8450070B2 (en) | 2007-12-28 | 2013-05-28 | Takeda Pharmaceutical Company Limited | Method for screening of cell-protecting agent |
EP2228368A1 (fr) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-ph2nyl2thoxy)hexyl]amino}-1-hydroxy2thyl)-8-hydroxyquinolin-2(1h)-one |
EP2578570A1 (fr) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Nouveau procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy)hexyl]amino}-1-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one via de nouveaux intermédiaires de synthèse |
EP2641900A1 (fr) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Nouvelles formes polymorphes de héminapadisylate de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy) hexyl]amino}-1-(R)-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one en tant qu'agoniste du récepteur adrénergique ß2 |
TW201512171A (zh) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | 化學化合物 |
US10085999B1 (en) | 2017-05-10 | 2018-10-02 | Arixa Pharmaceuticals, Inc. | Beta-lactamase inhibitors and uses thereof |
CN111448182A (zh) | 2017-10-02 | 2020-07-24 | 阿里萨制药有限公司 | 氨曲南衍生物及其用途 |
WO2020072442A1 (fr) | 2018-10-01 | 2020-04-09 | Arixa Pharmaceuticals, Inc. | Dérivés de relebactam et utilisations associées |
CN110156620B (zh) * | 2019-07-02 | 2022-04-15 | 中节能万润股份有限公司 | 一种氨甲环酸的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179276A (en) * | 1977-02-01 | 1979-12-18 | E. I. Du Pont De Nemours And Company | Novel imidazothiazine-1,3 (2H)-diones |
GB9212486D0 (en) * | 1992-06-12 | 1992-07-22 | Erba Carlo Spa | Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation |
GB9410469D0 (en) * | 1994-05-25 | 1994-07-13 | Erba Farmitalia | Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation |
AU3106997A (en) * | 1996-06-14 | 1998-01-07 | Kaken Pharmaceutical Co., Ltd. | Bicyclic hydantoin derivatives, intermediates for the preparation thereof, process for the preparation of them, and herbicides containing the same as active ingredient |
EP0931074B1 (fr) * | 1996-09-06 | 2003-05-07 | Takeda Chemical Industries, Ltd. | 4,5,6,7-tetrahydrobenzo c]thiopenes condenses utilises comme renfor ateurs de l'action des facteurs induisant la differenciation cellulaire |
PT977745E (pt) * | 1998-03-04 | 2005-04-29 | Pharmacia Corp | Compostos de acido tioarilo sulfonamida hidroxamico |
EP1307455B1 (fr) * | 1999-10-20 | 2005-04-06 | Tanabe Seiyaku Co., Ltd. | Inhibiteurs d'adhesion cellulaire induite par alpha-l beta-2 |
-
2002
- 2002-05-14 WO PCT/JP2002/004640 patent/WO2002092606A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2002092606A1 (fr) | 2002-11-21 |
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