WO2002081695A3 - Genes that are modulated by posttranscriptional gene silencing - Google Patents

Genes that are modulated by posttranscriptional gene silencing Download PDF

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Publication number
WO2002081695A3
WO2002081695A3 PCT/EP2002/003806 EP0203806W WO02081695A3 WO 2002081695 A3 WO2002081695 A3 WO 2002081695A3 EP 0203806 W EP0203806 W EP 0203806W WO 02081695 A3 WO02081695 A3 WO 02081695A3
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WO
WIPO (PCT)
Prior art keywords
gene silencing
modulated
genes
posttranscriptional gene
posttranscriptional
Prior art date
Application number
PCT/EP2002/003806
Other languages
French (fr)
Other versions
WO2002081695A2 (en
Inventor
Tong Zhu
Evgueni Alexandrovich Glazov
Frederick Meins
Xun Wang
Hur-Song Chang
Original Assignee
Syngenta Participations Ag
Novartis Forschungsstiftung
Tong Zhu
Evgueni Alexandrovich Glazov
Frederick Meins
Xun Wang
Hur-Song Chang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag, Novartis Forschungsstiftung, Tong Zhu, Evgueni Alexandrovich Glazov, Frederick Meins, Xun Wang, Hur-Song Chang filed Critical Syngenta Participations Ag
Publication of WO2002081695A2 publication Critical patent/WO2002081695A2/en
Publication of WO2002081695A3 publication Critical patent/WO2002081695A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides a method to identify genes that are modulated by posttranscriptional gene silencing as well as regulatory elements and methods to modulate gene expression by posttranscriptional gene silencing.
PCT/EP2002/003806 2001-04-06 2002-04-05 Genes that are modulated by posttranscriptional gene silencing WO2002081695A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28204901P 2001-04-06 2001-04-06
US60/282,049 2001-04-06

Publications (2)

Publication Number Publication Date
WO2002081695A2 WO2002081695A2 (en) 2002-10-17
WO2002081695A3 true WO2002081695A3 (en) 2003-09-04

Family

ID=23079886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/003806 WO2002081695A2 (en) 2001-04-06 2002-04-05 Genes that are modulated by posttranscriptional gene silencing

Country Status (1)

Country Link
WO (1) WO2002081695A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL155588A0 (en) * 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US7598429B2 (en) 2001-04-18 2009-10-06 Mendel Biotechnology, Inc. Transcription factor sequences for conferring advantageous properties to plants
US7855164B1 (en) 2005-02-22 2010-12-21 Mendel Biotechnology, Inc. Screening methods employing stress-related promoters
JP4528953B2 (en) * 2008-08-29 2010-08-25 独立行政法人産業技術総合研究所 Dwarfing transformed plants and genes for inducing dwarfing
CN109182347B (en) * 2018-09-11 2020-07-24 中国农业科学院烟草研究所 Application of tobacco NtTS3 gene in controlling tobacco leaf senescence
CN110117604A (en) * 2019-04-29 2019-08-13 贵州大学 A kind of recombinant vector and expression of tea tree heat shock protein CssHSP-6 gene
CN114516907B (en) * 2020-11-20 2024-03-29 中国科学技术大学 Plant stress resistance related gene ATAGL70, and encoding protein and application thereof
CN112541048B (en) * 2020-12-17 2022-04-19 武汉中海庭数据技术有限公司 High-precision map stop line fusion method, system, server and storage medium

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015682A2 (en) * 1997-09-22 1999-04-01 Plant Bioscience Limited Gene silencing materials and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015682A2 (en) * 1997-09-22 1999-04-01 Plant Bioscience Limited Gene silencing materials and methods

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DALMAY TAMAS ET AL: "SDE3 encodes an RNA helicase required for post-transcriptional gene silencing in Arabidopsis.", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 20, no. 8, 17 April 2001 (2001-04-17), pages 2069 - 2077, XP002223333, ISSN: 0261-4189 *
FAGARD MATHILDE ET AL: "AGO1, QDE-2, and RDE-1 are related proteins required for post-transcriptional gene silencing in plants, quelling in fungi, and RNA interference in animals.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 97, no. 21, 10 October 2000 (2000-10-10), October 10, 2000, pages 11650 - 11654, XP002223351, ISSN: 0027-8424 *
FURNER IAN J ET AL: "Gene silencing and homology-dependent gene silencing in Arabidopsis: Genetic modifiers and DNA methylation.", GENETICS, vol. 149, no. 2, June 1998 (1998-06-01), pages 651 - 662, XP002223334, ISSN: 0016-6731 *
GARCIA-SANZ JOSE A ET AL: "Translational control: A general mechanism for gene regulation during T cell activation.", FASEB JOURNAL, vol. 12, no. 3, March 1998 (1998-03-01), pages 299 - 306, XP002223335, ISSN: 0892-6638 *
VAUCHERET HERVE ET AL: "Transcriptional gene silencing in plants: Targets, inducers and regulators.", TRENDS IN GENETICS, vol. 17, no. 1, January 2001 (2001-01-01), pages 29 - 35, XP002223336, ISSN: 0168-9525 *

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Publication number Publication date
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