WO2002079418A3 - Gene regulation ii - Google Patents

Gene regulation ii Download PDF

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Publication number
WO2002079418A3
WO2002079418A3 PCT/US2002/009703 US0209703W WO02079418A3 WO 2002079418 A3 WO2002079418 A3 WO 2002079418A3 US 0209703 W US0209703 W US 0209703W WO 02079418 A3 WO02079418 A3 WO 02079418A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene regulation
expression
nucleic acid
target gene
heterologous nucleic
Prior art date
Application number
PCT/US2002/009703
Other languages
French (fr)
Other versions
WO2002079418A2 (en
WO2002079418A9 (en
Inventor
Yen Choo
John Girdlestone
Michael Moore
Original Assignee
Gendaq Ltd
Yen Choo
John Girdlestone
Michael Moore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gendaq Ltd, Yen Choo, John Girdlestone, Michael Moore filed Critical Gendaq Ltd
Priority to US10/473,238 priority Critical patent/US20050235369A1/en
Priority to AU2002306951A priority patent/AU2002306951A1/en
Publication of WO2002079418A2 publication Critical patent/WO2002079418A2/en
Publication of WO2002079418A9 publication Critical patent/WO2002079418A9/en
Publication of WO2002079418A3 publication Critical patent/WO2002079418A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

We describe a transgenic non-human animal comprising a heterologous nucleic acid binding polypeptide which binds to a target gene and modulates its expression, in which the heterologous nucleic acid binding polypeptide is encoded by a transgene, and in which the expression of a target gene in at least one cell is modulated compared to a non-transgenic animal.
PCT/US2002/009703 2001-03-28 2002-03-28 Gene regulation ii WO2002079418A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/473,238 US20050235369A1 (en) 2001-03-28 2002-03-28 Gene regulation II
AU2002306951A AU2002306951A1 (en) 2001-03-28 2002-03-28 Gene regulation ii

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0107757.7 2001-03-28
GB0107757A GB0107757D0 (en) 2001-03-28 2001-03-28 Gene regulation II

Publications (3)

Publication Number Publication Date
WO2002079418A2 WO2002079418A2 (en) 2002-10-10
WO2002079418A9 WO2002079418A9 (en) 2003-01-03
WO2002079418A3 true WO2002079418A3 (en) 2004-02-05

Family

ID=9911749

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009703 WO2002079418A2 (en) 2001-03-28 2002-03-28 Gene regulation ii

Country Status (3)

Country Link
AU (1) AU2002306951A1 (en)
GB (1) GB0107757D0 (en)
WO (1) WO2002079418A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003290689A1 (en) 2002-11-08 2004-06-03 Kyowa Hakko Kirin Co., Ltd. Transgenic ungulates having reduced prion protein activity and uses thereof
EP1526184A1 (en) * 2003-10-24 2005-04-27 Institut National De La Sante Et De La Recherche Medicale (Inserm) Promoter sequences specific for cells of the B lymphoid lineage and pharmaceutical compositions containing the same
CN102839214A (en) * 2012-09-06 2012-12-26 许汉鹏 Method for screening specific gene regulation correlated mechanism and molecule in eukaryon genome

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999028469A1 (en) * 1997-12-04 1999-06-10 Genzyme Corporation Compositions and methods for inducing gene expression
US5942433A (en) * 1995-07-31 1999-08-24 The United States Of America As Represented By The Department Of Health And Human Services Extension of a protein-protein interaction surface to inactivate the function of a cellular protein

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942433A (en) * 1995-07-31 1999-08-24 The United States Of America As Represented By The Department Of Health And Human Services Extension of a protein-protein interaction surface to inactivate the function of a cellular protein
WO1999028469A1 (en) * 1997-12-04 1999-06-10 Genzyme Corporation Compositions and methods for inducing gene expression

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBASE [online] SCHUH A.C. ET AL.: "Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice", XP002970318, accession no. STN Database accession no. 90256957 *
NATURE, vol. 346, no. 6286, 1990, pages 756 - 760 *

Also Published As

Publication number Publication date
WO2002079418A2 (en) 2002-10-10
AU2002306951A1 (en) 2002-10-15
WO2002079418A9 (en) 2003-01-03
GB0107757D0 (en) 2001-05-16

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