WO2002072824A3 - Regulation du canal potentiel humain du recepteur transitoire humain - Google Patents

Regulation du canal potentiel humain du recepteur transitoire humain Download PDF

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Publication number
WO2002072824A3
WO2002072824A3 PCT/EP2002/001727 EP0201727W WO02072824A3 WO 2002072824 A3 WO2002072824 A3 WO 2002072824A3 EP 0201727 W EP0201727 W EP 0201727W WO 02072824 A3 WO02072824 A3 WO 02072824A3
Authority
WO
WIPO (PCT)
Prior art keywords
transient receptor
receptor potential
potential channel
human transient
channel protein
Prior art date
Application number
PCT/EP2002/001727
Other languages
English (en)
Other versions
WO2002072824A2 (fr
Inventor
Timothy J Smith
Original Assignee
Bayer Ag
Timothy J Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Timothy J Smith filed Critical Bayer Ag
Priority to US10/467,163 priority Critical patent/US20040115675A1/en
Priority to AU2002233343A priority patent/AU2002233343A1/en
Publication of WO2002072824A2 publication Critical patent/WO2002072824A2/fr
Publication of WO2002072824A3 publication Critical patent/WO2002072824A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention porte sur des réactifs régulant le canal potentiel du récepteur transitoire humain et sur des réactifs se fixant aux produits géniques dudit canal potentiel, et pouvant jouer un rôle dans la prévention, l'amélioration, ou la correction des troubles ou maladies incluant non exclusivement le cancer, les troubles cardio-vasculaires et les troubles du SNC.
PCT/EP2002/001727 2001-02-20 2002-02-19 Regulation du canal potentiel humain du recepteur transitoire humain WO2002072824A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/467,163 US20040115675A1 (en) 2002-02-19 2002-02-19 Regulation of human transient receptor potential channel
AU2002233343A AU2002233343A1 (en) 2001-02-20 2002-02-19 Human transient receptor potential channel protein.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26941101P 2001-02-20 2001-02-20
US60/269,411 2001-02-20
US35002102P 2002-01-23 2002-01-23
US60/350,021 2002-01-23

Publications (2)

Publication Number Publication Date
WO2002072824A2 WO2002072824A2 (fr) 2002-09-19
WO2002072824A3 true WO2002072824A3 (fr) 2002-12-19

Family

ID=26953680

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/001727 WO2002072824A2 (fr) 2001-02-20 2002-02-19 Regulation du canal potentiel humain du recepteur transitoire humain

Country Status (2)

Country Link
AU (1) AU2002233343A1 (fr)
WO (1) WO2002072824A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223557B2 (en) 2001-05-22 2007-05-29 Bristol-Myers Squibb Company Polynucleotide encoding a TRP channel family member, TRP-PLIK2
JPWO2003033727A1 (ja) 2001-10-12 2005-02-03 山之内製薬株式会社 細胞死抑制剤スクリーニング法
US20050182011A1 (en) * 2003-11-13 2005-08-18 Eric Olson Inhibition of TRP channels as a treatment for cardiac hypertrophy and heart failure
BRPI0519807A2 (pt) 2005-01-12 2009-03-17 Sanofi Aventis uso de um canal trpc para o tratamento de uma doença cardiovascular
US8221753B2 (en) 2009-09-30 2012-07-17 Tracon Pharmaceuticals, Inc. Endoglin antibodies
UA115789C2 (uk) 2012-09-05 2017-12-26 Трейкон Фармасутікалз, Інк. Композиція антитіла до cd105 та її застосування
US10214590B2 (en) 2013-09-20 2019-02-26 Tufts Medical Center, Inc. Inhibitors of endoglin activity for the treatment of fibrosis
CA2966905A1 (fr) 2014-11-12 2016-05-19 Tracon Pharmaceuticals, Inc. Anticorps anti-endogline et leurs utilisations
US9926375B2 (en) 2014-11-12 2018-03-27 Tracon Pharmaceuticals, Inc. Anti-endoglin antibodies and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL_HUM 10 April 2001 (2001-04-10), RYAZANOV A G: "Homo sapiens channel kinase 3 (CHAK2) mRNA, complete cds", XP002213175 *
DATABASE EMBL_HUM 29 September 2000 (2000-09-29), SUGANO S ET AL: "Homo sapiens cDNA: FLJ22628 fis, clone HSI06177", XP002213173 *
DATABASE MEDLINE [online] March 2001 (2001-03-01), RIAZANOVA L V ET AL: "[Novel type of signaling molecules: protein kinases covalently linked to ion channels]", XP002213174, Database accession no. NLM11357414 *
HARTENECK C ET AL: "FROM WORM TO MAN: THREE SUBFAMILIES OF TRP CHANNELS", TRENDS IN NEUROSCIENCE, ELSEVIER, AMSTERDAM, NL, vol. 23, no. 4, April 2000 (2000-04-01), pages 159 - 166, XP001018915, ISSN: 0166-2236 *
MOLEKULIARNAIA BIOLOGIIA. RUSSIA 2001 MAR-APR, vol. 35, no. 2, March 2001 (2001-03-01), pages 321 - 332, ISSN: 0026-8984 *
NAGAMINE K ET AL: "MOLECULAR CLONING OF A NOVEL PUTATIVE CA2+ CHANNEL PROTEIN (TRPC7) HIGHLY EXPRESSED IN BRAIN", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 54, no. 1, 1998, pages 124 - 131, XP000938744, ISSN: 0888-7543 *
SCHLINGMANN KARL P ET AL: "Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family.", NATURE GENETICS. UNITED STATES JUN 2002, vol. 31, no. 2, June 2002 (2002-06-01), pages 166 - 170, XP001104558, ISSN: 1061-4036 *

Also Published As

Publication number Publication date
AU2002233343A1 (en) 2002-09-24
WO2002072824A2 (fr) 2002-09-19

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