WO2002055681A3 - Regulation de la tau-tubuline kinase humaine - Google Patents
Regulation de la tau-tubuline kinase humaine Download PDFInfo
- Publication number
- WO2002055681A3 WO2002055681A3 PCT/EP2002/000157 EP0200157W WO02055681A3 WO 2002055681 A3 WO2002055681 A3 WO 2002055681A3 EP 0200157 W EP0200157 W EP 0200157W WO 02055681 A3 WO02055681 A3 WO 02055681A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- human tau
- tubulin kinase
- regulation
- reagents
- tubulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002231741A AU2002231741A1 (en) | 2001-01-11 | 2002-01-10 | Regulation of human tau-tubulin kinase |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26064901P | 2001-01-11 | 2001-01-11 | |
US60/260,649 | 2001-01-11 | ||
US30761501P | 2001-07-26 | 2001-07-26 | |
US60/307,615 | 2001-07-26 | ||
US31383001P | 2001-08-22 | 2001-08-22 | |
US60/313,830 | 2001-08-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002055681A2 WO2002055681A2 (fr) | 2002-07-18 |
WO2002055681A3 true WO2002055681A3 (fr) | 2003-03-27 |
Family
ID=27401332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/000157 WO2002055681A2 (fr) | 2001-01-11 | 2002-01-10 | Regulation de la tau-tubuline kinase humaine |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002231741A1 (fr) |
WO (1) | WO2002055681A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003023034A2 (fr) * | 2001-09-12 | 2003-03-20 | Bayer Healthcare Ag | Regulation de tau-tubuline kinase humaine |
JOP20200228A1 (ar) | 2015-12-21 | 2017-06-16 | Novartis Ag | تركيبات وطرق لخفض تعبير البروتين tau |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000073469A2 (fr) * | 1999-05-28 | 2000-12-07 | Sugen, Inc. | Proteines kinases |
WO2001073050A2 (fr) * | 2000-03-24 | 2001-10-04 | Millennium Pharmaceuticals, Inc. | 3714, 16742, 23546, et 13887 nouvelles molecules de proteine kinase et leurs utilisations |
-
2002
- 2002-01-10 AU AU2002231741A patent/AU2002231741A1/en not_active Abandoned
- 2002-01-10 WO PCT/EP2002/000157 patent/WO2002055681A2/fr not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000073469A2 (fr) * | 1999-05-28 | 2000-12-07 | Sugen, Inc. | Proteines kinases |
WO2001073050A2 (fr) * | 2000-03-24 | 2001-10-04 | Millennium Pharmaceuticals, Inc. | 3714, 16742, 23546, et 13887 nouvelles molecules de proteine kinase et leurs utilisations |
Non-Patent Citations (4)
Title |
---|
MORISHIMA-KAWASHIMA MAHO ET AL: "Proline-directed and non-proline-directed phosphorylation of PHF-tau.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 2, 1995, pages 823 - 829, XP002224023, ISSN: 0021-9258 * |
REYNOLDS C HUGH ET AL: "Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: Differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and p38, and glycogen synthase kinase-3beta.", JOURNAL OF NEUROCHEMISTRY, vol. 74, no. 4, April 2000 (2000-04-01), pages 1587 - 1595, XP002224024, ISSN: 0022-3042 * |
TAKAHASHI MIHO ET AL: "A novel tau-tubulin kinase from bovine brain.", FEBS LETTERS, vol. 372, no. 1, 1995, pages 59 - 64, XP002224022, ISSN: 0014-5793 * |
TOMIZAWA KAYOKO ET AL: "Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau.", FEBS LETTERS, vol. 492, no. 3, March 2001 (2001-03-01), pages 221 - 227, XP002224031, ISSN: 0014-5793 * |
Also Published As
Publication number | Publication date |
---|---|
WO2002055681A2 (fr) | 2002-07-18 |
AU2002231741A1 (en) | 2002-07-24 |
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