WO2002055681A2 - Regulation de la tau-tubuline kinase humaine - Google Patents

Regulation de la tau-tubuline kinase humaine Download PDF

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Publication number
WO2002055681A2
WO2002055681A2 PCT/EP2002/000157 EP0200157W WO02055681A2 WO 2002055681 A2 WO2002055681 A2 WO 2002055681A2 EP 0200157 W EP0200157 W EP 0200157W WO 02055681 A2 WO02055681 A2 WO 02055681A2
Authority
WO
WIPO (PCT)
Prior art keywords
tau
polypeptide
tubulin kinase
seq
polynucleotide
Prior art date
Application number
PCT/EP2002/000157
Other languages
English (en)
Other versions
WO2002055681A3 (fr
Inventor
Jiing-Ren Liou
Original Assignee
Bayer Ag
Jiing-Ren Liou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Jiing-Ren Liou filed Critical Bayer Ag
Priority to AU2002231741A priority Critical patent/AU2002231741A1/en
Publication of WO2002055681A2 publication Critical patent/WO2002055681A2/fr
Publication of WO2002055681A3 publication Critical patent/WO2002055681A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne des réactifs qui régulent la tau-tubuline kinase humaine, ainsi que des réactifs qui se lient avec les produits géniques de la tau-tubuline kinase humaine. Ces réactifs peuvent jouer un rôle dans la prévention, l'amélioration ou la correction de dysfonctions ou de pathologies, notamment mais non exclusivement la BPCO, les troubles du système nerveux périphérique et central, et les maladies cardio-vasculaires.
PCT/EP2002/000157 2001-01-11 2002-01-10 Regulation de la tau-tubuline kinase humaine WO2002055681A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002231741A AU2002231741A1 (en) 2001-01-11 2002-01-10 Regulation of human tau-tubulin kinase

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US26064901P 2001-01-11 2001-01-11
US60/260,649 2001-01-11
US30761501P 2001-07-26 2001-07-26
US60/307,615 2001-07-26
US31383001P 2001-08-22 2001-08-22
US60/313,830 2001-08-22

Publications (2)

Publication Number Publication Date
WO2002055681A2 true WO2002055681A2 (fr) 2002-07-18
WO2002055681A3 WO2002055681A3 (fr) 2003-03-27

Family

ID=27401332

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/000157 WO2002055681A2 (fr) 2001-01-11 2002-01-10 Regulation de la tau-tubuline kinase humaine

Country Status (2)

Country Link
AU (1) AU2002231741A1 (fr)
WO (1) WO2002055681A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023034A2 (fr) * 2001-09-12 2003-03-20 Bayer Healthcare Ag Regulation de tau-tubuline kinase humaine
US11473083B2 (en) 2015-12-21 2022-10-18 Novartis Ag Compositions and methods for decreasing tau expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383244A1 (fr) * 1999-05-28 2000-12-07 Sugen, Inc. Proteines kinases
EP1272640A2 (fr) * 2000-03-24 2003-01-08 Millennium Pharmaceuticals, Inc. 3714, 16742, 23546, et 13887 nouvelles molecules de proteine kinase et leurs utilisations

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003023034A2 (fr) * 2001-09-12 2003-03-20 Bayer Healthcare Ag Regulation de tau-tubuline kinase humaine
WO2003023034A3 (fr) * 2001-09-12 2003-10-16 Bayer Ag Regulation de tau-tubuline kinase humaine
US11473083B2 (en) 2015-12-21 2022-10-18 Novartis Ag Compositions and methods for decreasing tau expression

Also Published As

Publication number Publication date
AU2002231741A1 (en) 2002-07-24
WO2002055681A3 (fr) 2003-03-27

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