WO2002046436A3 - Plasmid vectors - Google Patents

Plasmid vectors Download PDF

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Publication number
WO2002046436A3
WO2002046436A3 PCT/US2001/046516 US0146516W WO0246436A3 WO 2002046436 A3 WO2002046436 A3 WO 2002046436A3 US 0146516 W US0146516 W US 0146516W WO 0246436 A3 WO0246436 A3 WO 0246436A3
Authority
WO
WIPO (PCT)
Prior art keywords
plasmid vectors
bacteria
vectors
disclosure
cyanobacterium
Prior art date
Application number
PCT/US2001/046516
Other languages
French (fr)
Other versions
WO2002046436A2 (en
WO2002046436A9 (en
Inventor
Katherine S Bowdish
Shana Barbas-Frederickson
Martha Wild
John Mcwhirter
Original Assignee
Alexion Pharma Inc
Katherine S Bowdish
Shana Barbas-Frederickson
Martha Wild
John Mcwhirter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexion Pharma Inc, Katherine S Bowdish, Shana Barbas-Frederickson, Martha Wild, John Mcwhirter filed Critical Alexion Pharma Inc
Priority to AU2002218022A priority Critical patent/AU2002218022A1/en
Publication of WO2002046436A2 publication Critical patent/WO2002046436A2/en
Publication of WO2002046436A3 publication Critical patent/WO2002046436A3/en
Publication of WO2002046436A9 publication Critical patent/WO2002046436A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

This disclosure describes novel vectors capable or replication and expression of foreign genetic information in bacteria, such as, for example, cyanobacterium and E. coli. This disclosure also deals with the use of the vectors to introduce foreign genes into bacteria.
PCT/US2001/046516 2000-12-08 2001-12-07 Plasmid vectors WO2002046436A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002218022A AU2002218022A1 (en) 2000-12-08 2001-12-07 Plasmid vectors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25441100P 2000-12-08 2000-12-08
US60/254,411 2000-12-08

Publications (3)

Publication Number Publication Date
WO2002046436A2 WO2002046436A2 (en) 2002-06-13
WO2002046436A3 true WO2002046436A3 (en) 2003-03-06
WO2002046436A9 WO2002046436A9 (en) 2003-04-17

Family

ID=22964211

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046516 WO2002046436A2 (en) 2000-12-08 2001-12-07 Plasmid vectors

Country Status (2)

Country Link
AU (1) AU2002218022A1 (en)
WO (1) WO2002046436A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011317A1 (en) * 1993-10-19 1995-04-27 The Scripps Research Institute Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus
WO2002046435A2 (en) * 2000-12-05 2002-06-13 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011317A1 (en) * 1993-10-19 1995-04-27 The Scripps Research Institute Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus
WO2002046435A2 (en) * 2000-12-05 2002-06-13 Alexion Pharmaceuticals, Inc. Engineered plasmids and their use for in situ production of genes

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI, Hinxton, UK; 3 October 2000 (2000-10-03), RADER ET AL.: "Phagemid cloning vector pComb3X", XP002222421, Database accession no. AF268281 *
DUEÑEAS M ET AL: "A point mutation in a murine immunoglobulin V-region strongly influences the antibody yield in Escherichia coli", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 158, no. 1, 1995, pages 61 - 66, XP004206659, ISSN: 0378-1119 *
FIORENTINI S ET AL: "Humanization of an antibody recognizing a breast cancer specific epitope by CDR-grafting", IMMUNOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS BV, NL, vol. 3, no. 1, 1 March 1997 (1997-03-01), pages 45 - 59, XP004075438, ISSN: 1380-2933 *
KANG A S ET AL: "LINKAGE OF RECOGNITION AND REPLICATION FUNCTIONS BY ASSEMBLING COMBINATORIAL ANTIBODY FAB LIBRARIES ALONG PHAGE SURFACES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 88, no. 10, 1991, 1991, pages 4363 - 4366, XP002222017, ISSN: 0027-8424 *
KIPRIYANOV S M ET AL: "High level production of soluble single chain antibodies in small-scale Escherichia coli cultures", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 200, no. 1, 15 January 1997 (1997-01-15), pages 69 - 77, XP004016732, ISSN: 0022-1759 *

Also Published As

Publication number Publication date
WO2002046436A2 (en) 2002-06-13
WO2002046436A9 (en) 2003-04-17
AU2002218022A1 (en) 2002-06-18

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