WO2002038810A3 - Compositions and methods relating to prostate specific genes and proteins - Google Patents

Compositions and methods relating to prostate specific genes and proteins Download PDF

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Publication number
WO2002038810A3
WO2002038810A3 PCT/US2001/047001 US0147001W WO0238810A3 WO 2002038810 A3 WO2002038810 A3 WO 2002038810A3 US 0147001 W US0147001 W US 0147001W WO 0238810 A3 WO0238810 A3 WO 0238810A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
compositions
antagonists
nucleic acids
agonists
Prior art date
Application number
PCT/US2001/047001
Other languages
French (fr)
Other versions
WO2002038810A2 (en
Inventor
Yongming Sun
Herve Recipon
Sei-Yu Chen
Chenghua Liu
Original Assignee
Diadexus Inc
Yongming Sun
Herve Recipon
Sei-Yu Chen
Chenghua Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diadexus Inc, Yongming Sun, Herve Recipon, Sei-Yu Chen, Chenghua Liu filed Critical Diadexus Inc
Priority to AU2002235164A priority Critical patent/AU2002235164A1/en
Publication of WO2002038810A2 publication Critical patent/WO2002038810A2/en
Publication of WO2002038810A3 publication Critical patent/WO2002038810A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic prostate cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating prostate cancer and non-cancerous disease states in prostate tissue, identifying prostate tissue, monitoring an didentifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered prostate tissue for treatment and research.
PCT/US2001/047001 2000-11-06 2001-11-06 Compositions and methods relating to prostate specific genes and proteins WO2002038810A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002235164A AU2002235164A1 (en) 2000-11-06 2001-11-06 Compositions and methods relating to prostate specific genes and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24610900P 2000-11-06 2000-11-06
US60/246,109 2000-11-06

Publications (2)

Publication Number Publication Date
WO2002038810A2 WO2002038810A2 (en) 2002-05-16
WO2002038810A3 true WO2002038810A3 (en) 2003-12-04

Family

ID=22929338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/047001 WO2002038810A2 (en) 2000-11-06 2001-11-06 Compositions and methods relating to prostate specific genes and proteins

Country Status (2)

Country Link
AU (1) AU2002235164A1 (en)
WO (1) WO2002038810A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0428187D0 (en) * 2004-12-23 2005-01-26 Univ Liverpool Cancer treatment

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999060162A1 (en) * 1998-05-21 1999-11-25 Diadexus Llc A novel method of diagnosing, monitoring, and staging prostate cancer
WO2000047773A1 (en) * 1999-02-09 2000-08-17 Urocor, Inc. A novel, prostate-specific gene for diagnosis, prognosis and management of prostate cancer
WO2000058470A1 (en) * 1999-03-26 2000-10-05 Henry M. Jackson Foundation For The Advancement Of Military Medicine Prostate-specific gene, pcgem1, and methods of using pcgem1 to detect, treat, and prevent prostate cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999060162A1 (en) * 1998-05-21 1999-11-25 Diadexus Llc A novel method of diagnosing, monitoring, and staging prostate cancer
WO2000047773A1 (en) * 1999-02-09 2000-08-17 Urocor, Inc. A novel, prostate-specific gene for diagnosis, prognosis and management of prostate cancer
WO2000058470A1 (en) * 1999-03-26 2000-10-05 Henry M. Jackson Foundation For The Advancement Of Military Medicine Prostate-specific gene, pcgem1, and methods of using pcgem1 to detect, treat, and prevent prostate cancer

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BUSSEMAKERS M J G ET AL: "DD3: NEW PROSTATE-SPECIFIC GENE, HIGHLY OVEREXPRESSED IN PROSTATE CANCER", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 59, 1 December 1999 (1999-12-01), pages 5975 - 5979, XP002923011, ISSN: 0008-5472 *
DATABASE EMBL [online] 23 March 2000 (2000-03-23), XP002238709, retrieved from WWW.EBI.AC.UK Database accession no. AP001491 *
HUBERT R S ET AL: "STEAP: A PROSTATE-SPECIFIC CELL-SURFACE ANTIGEN HIGHLY EXPRESSED IN HUMAN PROSTATE TUMORS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 25, 7 December 1999 (1999-12-07), pages 14523 - 14528, XP000946864, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU2002235164A1 (en) 2002-05-21
WO2002038810A2 (en) 2002-05-16

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