WO2003020899A3 - Compositions and methods relating to lung specific genes and proteins - Google Patents

Compositions and methods relating to lung specific genes and proteins Download PDF

Info

Publication number
WO2003020899A3
WO2003020899A3 PCT/US2002/027771 US0227771W WO03020899A3 WO 2003020899 A3 WO2003020899 A3 WO 2003020899A3 US 0227771 W US0227771 W US 0227771W WO 03020899 A3 WO03020899 A3 WO 03020899A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
lung
compositions
antagonists
agonists
Prior art date
Application number
PCT/US2002/027771
Other languages
French (fr)
Other versions
WO2003020899A2 (en
Inventor
Yongming Sun
Chenghua Liu
Sei-Yu Chen
Original Assignee
Diadexus Inc
Yongming Sun
Chenghua Liu
Sei-Yu Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diadexus Inc, Yongming Sun, Chenghua Liu, Sei-Yu Chen filed Critical Diadexus Inc
Priority to AU2002331780A priority Critical patent/AU2002331780A1/en
Publication of WO2003020899A2 publication Critical patent/WO2003020899A2/en
Publication of WO2003020899A3 publication Critical patent/WO2003020899A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to newly identified nucleic acid molecules and polypeptides present in normal and neoplastic lung cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention, also relates to compositions containing the nucleic acid molecules, polypeptides, antibodies, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating lung cancer and non-cancerous disease states in lung, identifying lung tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered lung tissue for treatment and research.
PCT/US2002/027771 2001-08-31 2002-08-29 Compositions and methods relating to lung specific genes and proteins WO2003020899A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002331780A AU2002331780A1 (en) 2001-08-31 2002-08-29 Compositions and methods relating to lung specific genes and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31626001P 2001-08-31 2001-08-31
US60/316,260 2001-08-31

Publications (2)

Publication Number Publication Date
WO2003020899A2 WO2003020899A2 (en) 2003-03-13
WO2003020899A3 true WO2003020899A3 (en) 2004-02-26

Family

ID=23228279

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/027771 WO2003020899A2 (en) 2001-08-31 2002-08-29 Compositions and methods relating to lung specific genes and proteins

Country Status (2)

Country Link
AU (1) AU2002331780A1 (en)
WO (1) WO2003020899A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI121236B (en) * 2006-01-18 2010-08-31 Licentia Oy Procedure for detecting lung cancer caused by exposure to asbestos
EP3013963B1 (en) * 2013-06-24 2017-07-05 Azargen Biotechnologies (Pty) Ltd. Production of human pulmonary surfactant protein b in plants
US9670497B2 (en) * 2014-05-19 2017-06-06 Azargen Biotechnologies (Pty) Ltd. Synthetic promoter construct for transgene expression

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840506A (en) * 1996-06-05 1998-11-24 Thomas Jefferson University Methods for the diagnosis and prognosis of cancer
US6225051B1 (en) * 1996-04-16 2001-05-01 Haruo Sugiyama Method of detecting solid cancer cells and tissue atypia and method of testing tissues for use in bone marrow transplantation and peripheral blood stem cell transplantation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225051B1 (en) * 1996-04-16 2001-05-01 Haruo Sugiyama Method of detecting solid cancer cells and tissue atypia and method of testing tissues for use in bone marrow transplantation and peripheral blood stem cell transplantation
US5840506A (en) * 1996-06-05 1998-11-24 Thomas Jefferson University Methods for the diagnosis and prognosis of cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MAHAIRAS ET AL.: "Sequence-tagged connectors: a sequence approach to mapping and scanning the human genome", PROC. NATL. ACAD. SCI. USA, vol. 96, August 1999 (1999-08-01), pages 9739 - 9744, XP002931739 *

Also Published As

Publication number Publication date
WO2003020899A2 (en) 2003-03-13
AU2002331780A1 (en) 2003-03-18

Similar Documents

Publication Publication Date Title
WO2004053079A3 (en) Compositions, splice variants and methods relating to ovarian specific genes and proteins
WO2002062945A3 (en) Compositions and methods relating to lung specific genes and proteins
WO2002064741A3 (en) Compositions and methods relating to breast specific genes and proteins
WO2002040673A3 (en) Compositions and methods relating to lung specific genes and proteins
WO2002077232A3 (en) Compositions and methods relating to breast specific genes and proteins
WO2004053075A3 (en) Compositions, splice variants and methods relating to breast specific genes and proteins
WO2004050860A3 (en) Compositions, splice variants and methods relating to colon specific genes and proteins
WO2005017102A3 (en) Compositions, splice variants and methods relating to ovarian specific nucleic acids and proteins
WO2004013311A3 (en) Compositions and methods relating to ovarian specific genes and proteins
WO2003106648A3 (en) Compositions and methods relating to breast specific genes and proteins
WO2003066877A3 (en) Compositions and methods relating to hepatic specific genes and proteins
WO2002064788A3 (en) Compositions and methods relating to lung specific genes and proteins
WO2004050858A3 (en) Compositions, splice variants and methods relating to colon specific genes and proteins
WO2004052290A3 (en) Compositions, splice variants and methods relating to breast specific genes and proteins
WO2003020899A3 (en) Compositions and methods relating to lung specific genes and proteins
WO2003020953A3 (en) Compositions and methods relating to colon specific genes and proteins
WO2002068645A8 (en) Compositions and methods relating to breast specific genes and proteins
WO2002039431A3 (en) Compositions and methods relating to prostate specific genes and proteins
WO2004053077A3 (en) Compositions,splice variants and methods relating to breast specific genes and proteins
WO2002046224A3 (en) Compositions and methods relating to lung specific genes and proteins
WO2003060081A3 (en) Compositions and methods relating to endometrial specific genes and proteins
WO2003055982A3 (en) Compositions and methods relating to endometrial specific genes and proteins
WO2003060121A3 (en) Compositions and methods relating to gastric specific genes and proteins
WO2003020901A3 (en) Compositions and methods relating to prostate specific genes and proteins
WO2002066605A3 (en) Compositions and methods relating to breast specific genes and proteins

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VN YU ZA ZM

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP