WO2002036632A8 - Single nucleotide polymorphisms in nucleic acids encoding human olfactory receptor-like polypeptides - Google Patents

Single nucleotide polymorphisms in nucleic acids encoding human olfactory receptor-like polypeptides

Info

Publication number
WO2002036632A8
WO2002036632A8 PCT/US2001/031744 US0131744W WO0236632A8 WO 2002036632 A8 WO2002036632 A8 WO 2002036632A8 US 0131744 W US0131744 W US 0131744W WO 0236632 A8 WO0236632 A8 WO 0236632A8
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
single nucleotide
nucleotide polymorphisms
olfactory receptor
nucleic acids
Prior art date
Application number
PCT/US2001/031744
Other languages
French (fr)
Other versions
WO2002036632A2 (en
WO2002036632A3 (en
Inventor
John P Ii Alsobrook
Catherine E Burgess
William M Grosse
Denise M Lepley
Muralidhara Padigaru
Kimberly A Spytek
Original Assignee
Curagen Corp
John P Ii Alsobrook
Catherine E Burgess
William M Grosse
Denise M Lepley
Muralidhara Padigaru
Kimberly A Spytek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/777,789 external-priority patent/US20030087815A1/en
Application filed by Curagen Corp, John P Ii Alsobrook, Catherine E Burgess, William M Grosse, Denise M Lepley, Muralidhara Padigaru, Kimberly A Spytek filed Critical Curagen Corp
Priority to AU2001296804A priority Critical patent/AU2001296804A1/en
Publication of WO2002036632A2 publication Critical patent/WO2002036632A2/en
Publication of WO2002036632A8 publication Critical patent/WO2002036632A8/en
Publication of WO2002036632A3 publication Critical patent/WO2002036632A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides novel isolated nucleic acid sequences having single nucleotide polymorphisms that encode olfactory receptor-like polypeptides and the polypeptides so encoded. Also provided are the antibodies that immunospecifically bind to these polypeptides or any derivative, variant, mutant or fragment of the polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
PCT/US2001/031744 2000-11-02 2001-10-09 Single nucleotide polymorphisms in nucleic acids encoding human olfactory receptor-like polypeptides WO2002036632A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001296804A AU2001296804A1 (en) 2000-11-02 2001-10-09 Single nucleotide polymorphisms in nucleic acids encoding human olfactory receptor-like polypeptides

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US24529200P 2000-11-02 2000-11-02
US60/245,292 2000-11-02
US09/777,789 US20030087815A1 (en) 2000-02-07 2001-02-06 Novel polypeptides and nucleic acids encoding same
US09/777,789 2001-02-06
US32375501P 2001-09-20 2001-09-20
US60/323,755 2001-09-20

Publications (3)

Publication Number Publication Date
WO2002036632A2 WO2002036632A2 (en) 2002-05-10
WO2002036632A8 true WO2002036632A8 (en) 2002-09-06
WO2002036632A3 WO2002036632A3 (en) 2003-08-14

Family

ID=27399843

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/031744 WO2002036632A2 (en) 2000-11-02 2001-10-09 Single nucleotide polymorphisms in nucleic acids encoding human olfactory receptor-like polypeptides

Country Status (1)

Country Link
WO (1) WO2002036632A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106935A2 (en) * 2003-05-27 2004-12-09 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor 103 (gpr103)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874243A (en) * 1997-03-28 1999-02-23 Smithkline Beecham Corporation OLRCC15 receptor
WO2000021985A2 (en) * 1998-10-14 2000-04-20 Genset Genes encoding olfactory receptors and biallelic markers thereof
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
US20030211493A1 (en) * 2000-02-02 2003-11-13 Baughn Mariah R G-protein coupled receptors
US20030087815A1 (en) * 2000-02-07 2003-05-08 Muralidhara Padigaru Novel polypeptides and nucleic acids encoding same
JP2004504010A (en) * 2000-03-13 2004-02-12 セノミックス　インコーポレイテッド Human olfactory receptor and gene encoding the same
JP2004508843A (en) * 2000-09-22 2004-03-25 ケムコム　エス．エー． Olfactory and pheromone G protein-coupled receptors

Also Published As

Publication number Publication date
WO2002036632A2 (en) 2002-05-10
WO2002036632A3 (en) 2003-08-14

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