WO2002031151A3 - Lipocalins - Google Patents

Lipocalins Download PDF

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Publication number
WO2002031151A3
WO2002031151A3 PCT/US2001/031942 US0131942W WO0231151A3 WO 2002031151 A3 WO2002031151 A3 WO 2002031151A3 US 0131942 W US0131942 W US 0131942W WO 0231151 A3 WO0231151 A3 WO 0231151A3
Authority
WO
WIPO (PCT)
Prior art keywords
lipoc
provides
lipocalins
polynucleotides
agonists
Prior art date
Application number
PCT/US2001/031942
Other languages
French (fr)
Other versions
WO2002031151A2 (en
Inventor
Preeti G Lal
Narinder K Walia
Ameena R Gandhi
Yan Lu
Jayalaxmi Ramkumar
Mariah R Baughn
Christopher M Bruns
April J A Hafalia
Monique G Yao
Original Assignee
Incyte Genomics Inc
Preeti G Lal
Narinder K Walia
Ameena R Gandhi
Yan Lu
Jayalaxmi Ramkumar
Mariah R Baughn
Christopher M Bruns
April J A Hafalia
Monique G Yao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Preeti G Lal, Narinder K Walia, Ameena R Gandhi, Yan Lu, Jayalaxmi Ramkumar, Mariah R Baughn, Christopher M Bruns, April J A Hafalia, Monique G Yao filed Critical Incyte Genomics Inc
Priority to US10/399,455 priority Critical patent/US20040101872A1/en
Priority to EP01977737A priority patent/EP1325128A2/en
Priority to AU2001296831A priority patent/AU2001296831A1/en
Priority to CA002425767A priority patent/CA2425767A1/en
Priority to JP2002534519A priority patent/JP2004528813A/en
Publication of WO2002031151A2 publication Critical patent/WO2002031151A2/en
Publication of WO2002031151A3 publication Critical patent/WO2002031151A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides human lipocalins (LIPOC) and polynucleotides which identify and encode LIPOC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPOC.
PCT/US2001/031942 2000-10-13 2001-10-12 Lipocalins WO2002031151A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/399,455 US20040101872A1 (en) 2001-10-12 2001-10-12 Lipocalins
EP01977737A EP1325128A2 (en) 2000-10-13 2001-10-12 Lipocalins
AU2001296831A AU2001296831A1 (en) 2000-10-13 2001-10-12 Lipocalins
CA002425767A CA2425767A1 (en) 2000-10-13 2001-10-12 Lipocalins
JP2002534519A JP2004528813A (en) 2000-10-13 2001-10-12 Lipocalin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24054100P 2000-10-13 2000-10-13
US60/240,541 2000-10-13

Publications (2)

Publication Number Publication Date
WO2002031151A2 WO2002031151A2 (en) 2002-04-18
WO2002031151A3 true WO2002031151A3 (en) 2003-03-06

Family

ID=22906956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/031942 WO2002031151A2 (en) 2000-10-13 2001-10-12 Lipocalins

Country Status (5)

Country Link
EP (1) EP1325128A2 (en)
JP (1) JP2004528813A (en)
AU (1) AU2001296831A1 (en)
CA (1) CA2425767A1 (en)
WO (1) WO2002031151A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0217402D0 (en) * 2002-07-26 2002-09-04 Roslin Inst Edinburgh Multi-reporter gene model for toxicological screening
GB0426650D0 (en) * 2004-12-03 2005-01-05 Univ Cardiff Transgenic animals

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999007740A2 (en) * 1997-08-06 1999-02-18 Zymogenetics, Inc. Lipocalin homologs
WO2002018571A2 (en) * 2000-08-31 2002-03-07 Zymogenetics, Inc. Human phermone polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999007740A2 (en) * 1997-08-06 1999-02-18 Zymogenetics, Inc. Lipocalin homologs
WO2002018571A2 (en) * 2000-08-31 2002-03-07 Zymogenetics, Inc. Human phermone polypeptides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 6 March 2000 (2000-03-06), "Homo sapiens chromosome 9 clone RP11-100C15", XP002205323, retrieved from NCBI ENTREZ NUCLEOTIDE Database accession no. AL158822 *
GACHON AF: "lipocalines et transport de ligands hydrophobes", M/S MEDECINE SCIENCES, vol. 10, no. 1, 1994, pages 22 - 29, XP000892139 *
JULKUNEN M ET AL: "COMPLETE AMINO ACID SEQUENCE OF HUMAN PLACENTAL PROTEIN 14 A PROGESTERONE-REGULATED UTERINE PROTEIN HOMOLOGOUS TO BETA LACTOGLOBULINS", PROC.NATL.ACAD.SCI.USA, vol. 85, no. 23, 1988, pages 8845 - 8849, XP002164104, ISSN: 0027-8424 *
SHAHAN K. ET AL.: "Nucleotide sequences of liver, lachrymal, and submaxillary gland mouse Major Urinary Protein mRNAs: mosaic structure and construction of panels of gene-specific synthetic probes", MOLECULAR & CELLULAR BIOLOGY, vol. 7, no. 5, May 1987 (1987-05-01), pages 1938 - 1946, XP008005529 *

Also Published As

Publication number Publication date
CA2425767A1 (en) 2002-04-18
WO2002031151A2 (en) 2002-04-18
AU2001296831A1 (en) 2002-04-22
EP1325128A2 (en) 2003-07-09
JP2004528813A (en) 2004-09-24

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