WO2002018428A3 - Sequences which code for the sige gene of corynebacterium glutamicum - Google Patents

Sequences which code for the sige gene of corynebacterium glutamicum Download PDF

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Publication number
WO2002018428A3
WO2002018428A3 PCT/EP2001/008146 EP0108146W WO0218428A3 WO 2002018428 A3 WO2002018428 A3 WO 2002018428A3 EP 0108146 W EP0108146 W EP 0108146W WO 0218428 A3 WO0218428 A3 WO 0218428A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotide
sequences
code
amino acid
acid sequence
Prior art date
Application number
PCT/EP2001/008146
Other languages
French (fr)
Other versions
WO2002018428A2 (en
Inventor
Bettina Moeckel
Thomas Hermann
Mike Farwick
Michael Binder
Walter Pfefferle
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10126422A external-priority patent/DE10126422A1/en
Application filed by Degussa filed Critical Degussa
Priority to AU2001285843A priority Critical patent/AU2001285843A1/en
Priority to EP01965132A priority patent/EP1320616A2/en
Publication of WO2002018428A2 publication Critical patent/WO2002018428A2/en
Publication of WO2002018428A3 publication Critical patent/WO2002018428A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

Abstract

The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70% to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the sigE gene is present in enhanced form, and the use of polynucleotides which comprise the sequences according to the invention as hybridization probes.
PCT/EP2001/008146 2000-09-02 2001-07-14 Sequences which code for the sige gene of corynebacterium glutamicum WO2002018428A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001285843A AU2001285843A1 (en) 2000-09-02 2001-07-14 Sequences which code for the sige gene
EP01965132A EP1320616A2 (en) 2000-09-02 2001-07-14 Sequences which code for the sige gene of corynebacterium glutamicum

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10043336 2000-09-02
DE10043336.7 2000-09-02
DE10126422A DE10126422A1 (en) 2000-09-02 2001-05-31 Nucleotide sequences encoding the sigE gene
DE10126422.4 2001-05-31

Publications (2)

Publication Number Publication Date
WO2002018428A2 WO2002018428A2 (en) 2002-03-07
WO2002018428A3 true WO2002018428A3 (en) 2002-06-06

Family

ID=26006909

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/008146 WO2002018428A2 (en) 2000-09-02 2001-07-14 Sequences which code for the sige gene of corynebacterium glutamicum

Country Status (3)

Country Link
EP (1) EP1320616A2 (en)
AU (1) AU2001285843A1 (en)
WO (1) WO2002018428A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19548222A1 (en) * 1995-12-22 1997-06-26 Forschungszentrum Juelich Gmbh Process for the microbial production of amino acids through increased activity of export carriers
EP0864654A1 (en) * 1995-02-20 1998-09-16 Ajinomoto Co., Inc. Stress-tolerant microorganism and method of the production of fermentation product
EP1108790A2 (en) * 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Novel polynucleotides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0864654A1 (en) * 1995-02-20 1998-09-16 Ajinomoto Co., Inc. Stress-tolerant microorganism and method of the production of fermentation product
DE19548222A1 (en) * 1995-12-22 1997-06-26 Forschungszentrum Juelich Gmbh Process for the microbial production of amino acids through increased activity of export carriers
EP1108790A2 (en) * 1999-12-16 2001-06-20 Kyowa Hakko Kogyo Co., Ltd. Novel polynucleotides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL EBI; 7 May 1997 (1997-05-07), WU ET AL.: "Mycobacterium smegmatis extracytoplasmic function alternative sigma factor (sigE) gene", XP002188921 *
EGGELING L ET AL: "L-GLUTAMATE AND L-LYSINE: TRADITIONAL PRODUCTS WITH IMPETUOUS DEVELOPMENTS", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER VERLAG, BERLIN, DE, vol. 52, August 1999 (1999-08-01), pages 146 - 153, XP000979507, ISSN: 0175-7598 *
WU Q. ET AL: "A Mycobacterial extracytoplasmatic Sigma factor involved in survival following stress", J. BACTERIOL., vol. 179, no. 9, 1997, pages 2922 - 2929, XP002188920 *

Also Published As

Publication number Publication date
AU2001285843A1 (en) 2002-03-13
WO2002018428A2 (en) 2002-03-07
EP1320616A2 (en) 2003-06-25

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