WO2002013907A1 - Radiotherapy simulation apparatus - Google Patents
Radiotherapy simulation apparatus Download PDFInfo
- Publication number
- WO2002013907A1 WO2002013907A1 PCT/GB2001/003452 GB0103452W WO0213907A1 WO 2002013907 A1 WO2002013907 A1 WO 2002013907A1 GB 0103452 W GB0103452 W GB 0103452W WO 0213907 A1 WO0213907 A1 WO 0213907A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- imager
- accelerator
- patient
- simulator
- simulator according
- Prior art date
Links
- 238000001959 radiotherapy Methods 0.000 title claims abstract description 7
- 238000004088 simulation Methods 0.000 title description 6
- 230000005855 radiation Effects 0.000 claims abstract description 9
- 229910021417 amorphous silicon Inorganic materials 0.000 claims abstract description 3
- 238000000034 method Methods 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 2
- 238000002721 intensity-modulated radiation therapy Methods 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 238000002247 constant time method Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
- A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
- A61B6/4225—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using image intensifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/44—Constructional features of apparatus for radiation diagnosis
- A61B6/4429—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
- A61B6/4435—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
- A61B6/4441—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure the rigid structure being a C-arm or U-arm
Definitions
- the present invention relates to a radiotherapy apparatus.
- One such method is a simulator, a low energy source combined with a visible light source. An image can be prepared which corresponds to the therapeutic dose subsequently applied on the full scale accelerator. The visible light source allows the patient to be marked up for subsequent alignment. This form of simulation is suitable for simple treatment plans but is unable to simulate modern complex plans.
- portal image This is an image produced by placing a photographic plate or electronic imaging plate beneath the patient during a brief period of irradiation. The beam is attenuated by the patient's internal organs and structures, leaving an image in the plate. This can then be checked either before complete treatment or after a dose, to ensure that the aim was correct.
- Portal images are however extremely difficult to interpret as the energy of the beam which is necessary to have a useful therapeutic effect is very much greater than that used for medical imaging. At these higher energies there is smaller ratio in the relative attenuation between bony and tissue structure, which results in portal images with poor contrast. Structures within the patient are difficult to discern.
- CT computerised tomography
- a digitally reconstructed radiograph can be constructed that will be a prediction of the portal image that would be created.
- the DRR can be set up to enhance the contrast obtained and accordingly avoids the difficulties inherent in the portal image.
- dedicated CT scanners have an aperture limitation which means they cannot simulate the full range of the therapeutic accelerator.
- Simpler CT scanners based around a simulator can in theory simulate the full therapeutic range, but require a full rotation of the gantry to acquire each CT slice.
- the available speed of rotation of a simulator gantry means that it is only practical to obtain about 5 slices within a reasonable time. This is sufficient to cater for simple treatment plans but is inadequate for modern 3D treatment planning or Intensity Modulated Radiation Therapy (IMRT) treatment.
- IMRT Intensity Modulated Radiation Therapy
- CT scanners do not cast an image on the patient which can be used to mark up for later realignment.
- the present invention therefore provides a radiotherapy simulator comprising a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome.
- the accelerator can include an aligned visible light course to assist in patient mark-up.
- the imager is preferable of amorphous silicon. Such imagers are available as flat panel items.
- the accelerator and the imager are mounted on opposing arms of a C-shaped support. This provides a simple form of alignment which can be rotated around the patient easily.
- the imager arm is preferably retractable to allow easy access.
- patient 1 0 is supported on patient table 1 2 .
- a radiation source 14 capable of producing low energy radiation such as is normally used in simulation.
- Beneath the patient table 12 lies a planar digital detector 1 6 on a suitable support arrangement 1 8.
- the detector 1 6 is positioned so as to lie in the path of a beam of radiation 20 that has been omitted by the source 14 and has passed through the patient 10.
- the output of the detector 1 6 is fed to a computing apparatus 22.
- the radiation source 14 and detector 1 6 are mounted on the ends of a rotatable C-arm and can therefore be rotated in a corelated fashion around the patient, as shown in dotted lines.
- the two dimensional nature of the planar detector 1 6 means that a single rotational scan of the detector and the source will enable multiple slices to be reconstructed via cone beam CT methods.
- Cone beam reconstruction inherently has the same resolution in all directions and is therefore suited for generation of digitally reconstructed radiographs using the computing apparatus 22.
- the need for a DRR will in many cases be eliminated as the required image will be available directly from the detector, either as a by-product of the rotational scan or as a deliberate imaging action.
- the reconstruction process for generation of DRR is complex and therefore dedicated hardware within the computing apparatus is likely to be beneficial in order to reduce the reconstruction time into a period which is effectively on-line. However, it is also possible to generate the image off-line for subsequent use in planning.
- a source of optical light can be incorporated within radiation source 14 in order to provide one or more (preferably two or more) reference points for marking up the patient.
- the present invention provides a simulator which is able to produce a data set suitable for use in preparation of DRR's and treatment and planning which does not require extended CT scan times. Meanwhile, as opposed to existing scanners, the simulator is sufficiently similar to a treatment apparatus as to provide a reliable simulation process.
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
A radiotherapy simulator comprises a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome. The accelerator can include an aligned visible light course to assist in patient mark up. The imager is preferable of amorphous silicon. Such imagers are available as flat panel items. It is further preferred that the accelerator and the imager are mounted on opposing arms of a C-shaped support. This provides a simple form of alignment which can be rotated around the patient easily. The imager arm is preferably retractable to allow easy access.
Description
RADIOTHERAPY SIMULATION APPARATUS
The present invention relates to a radiotherapy apparatus.
In the use of radiotherapy to treat cancer and other ailments, a powerful beam of the appropriate radiation is directed at the area of the patient which is affected. This beam is apt to kill living cells in its path, hence its use against cancerous cells, and therefore it is highly desirable to ensure that the beam is correctly aimed. Failure to do so may result in the unnecessary destruction of healthy cells of the patient.
Several methods are used to check that the alignment of the beam is correct. One such method is a simulator, a low energy source combined with a visible light source. An image can be prepared which corresponds to the therapeutic dose subsequently applied on the full scale accelerator. The visible light source allows the patient to be marked up for subsequent alignment. This form of simulation is suitable for simple treatment plans but is unable to simulate modern complex plans.
Another method is the use of a so-called "portal image". This is an image produced by placing a photographic plate or electronic imaging plate beneath the patient during a brief period of irradiation. The beam is attenuated by the patient's
internal organs and structures, leaving an image in the plate. This can then be checked either before complete treatment or after a dose, to ensure that the aim was correct. Portal images are however extremely difficult to interpret as the energy of the beam which is necessary to have a useful therapeutic effect is very much greater than that used for medical imaging. At these higher energies there is smaller ratio in the relative attenuation between bony and tissue structure, which results in portal images with poor contrast. Structures within the patient are difficult to discern.
Another more recent approach is the use of CT simulation. A CT (computerised tomography) scanner is used to scan the patient. From the CT dataset, a digitally reconstructed radiograph (DRR) can be constructed that will be a prediction of the portal image that would be created. The DRR can be set up to enhance the contrast obtained and accordingly avoids the difficulties inherent in the portal image. However, dedicated CT scanners have an aperture limitation which means they cannot simulate the full range of the therapeutic accelerator. Simpler CT scanners based around a simulator can in theory simulate the full therapeutic range, but require a full rotation of the gantry to acquire each CT slice. The available speed of rotation of a simulator gantry means that it is only practical to obtain about 5 slices within a reasonable time. This is sufficient to cater for simple treatment plans but is inadequate for modern 3D treatment planning or Intensity Modulated Radiation Therapy (IMRT) treatment. In addition, CT scanners do not cast an image on the patient which can be used to mark up for later realignment.
Accordingly, there remains a need to provide a practical simulator which can accurately simulate complex treatment plans.
The present invention therefore provides a radiotherapy simulator comprising a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome.
The accelerator can include an aligned visible light course to assist in patient mark-up.
The imager is preferable of amorphous silicon. Such imagers are available as flat panel items.
It is further preferred that the accelerator and the imager are mounted on opposing arms of a C-shaped support. This provides a simple form of alignment which can be rotated around the patient easily. The imager arm is preferably retractable to allow easy access.
An embodiment of the present invention will now be described by way of example, with reference to the accompanying figure, which shows a schematic view of the system.
As shown in Figure 1 , patient 1 0 is supported on patient table 1 2 . Above the patient is disposed a radiation source 14 capable of producing low energy radiation such as is normally used in simulation. Beneath the patient table 12 lies a planar digital detector 1 6 on a suitable support arrangement 1 8. The detector 1 6 is positioned so as to lie in the path of a beam of radiation 20 that has been omitted by the source 14 and has passed through the patient 10. The output of the detector 1 6 is fed to a computing apparatus 22.
The radiation source 14 and detector 1 6 are mounted on the ends of a rotatable C-arm and can therefore be rotated in a corelated fashion around the patient, as shown in dotted lines. The two dimensional nature of the planar detector 1 6 means that a single rotational scan of the detector and the source will enable multiple slices to be reconstructed via cone beam CT methods. Cone beam reconstruction inherently has the same resolution in all directions and is therefore suited for generation of digitally reconstructed radiographs using the computing apparatus 22. However, the need for a DRR will in many cases be eliminated as
the required image will be available directly from the detector, either as a by-product of the rotational scan or as a deliberate imaging action.
The reconstruction process for generation of DRR is complex and therefore dedicated hardware within the computing apparatus is likely to be beneficial in order to reduce the reconstruction time into a period which is effectively on-line. However, it is also possible to generate the image off-line for subsequent use in planning.
A source of optical light can be incorporated within radiation source 14 in order to provide one or more (preferably two or more) reference points for marking up the patient.
Accordingly, the present invention provides a simulator which is able to produce a data set suitable for use in preparation of DRR's and treatment and planning which does not require extended CT scan times. Meanwhile, as opposed to existing scanners, the simulator is sufficiently similar to a treatment apparatus as to provide a reliable simulation process.
It will of course be appreciated that many variations can be made to the above described embodiment without departing from the scope of the present invention.
Claims
1 . A radiotherapy simulator comprising a radiation source and a planar digital detector together forming a cone beam CT arrangement, a patient support table lying between the accelerator and the imager, and a processing means adapted to interpret the output of the imager as a cone beam CT image to produce a simulated treatment outcome.
2. A simulator according to claim 1 including an aligned visible light source.
3. A simulator according to claim 1 or claim 2 in which the imager is of amorphous silicon.
4. A simulator according to any preceding claim in which the accelerator and the imager are mounted on opposing arms of a C-shaped support.
5. A simulator according to claim 4 in which the imager arm is retractable.
6. A simulator substantially as described herein with reference to and/or as illustrated in the accompanying figure.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0020030A GB2366501B (en) | 2000-08-16 | 2000-08-16 | Radiotherapy simulation apparatus |
GB0020030.3 | 2000-08-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002013907A1 true WO2002013907A1 (en) | 2002-02-21 |
Family
ID=9897610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2001/003452 WO2002013907A1 (en) | 2000-08-16 | 2001-07-31 | Radiotherapy simulation apparatus |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB2366501B (en) |
WO (1) | WO2002013907A1 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004004829A1 (en) * | 2002-07-02 | 2004-01-15 | Pencilbeam Technologies Ab | Radiation system with inner and outer gantry, to enable precise positioning when rotating the inner gantry |
EP1581804A2 (en) * | 2002-12-18 | 2005-10-05 | Varian Medical Systems Technologies, Inc. | A multi-mode cone beam ct radiotherapy simulator and treatment machine with a flat panel imager |
US9498167B2 (en) | 2005-04-29 | 2016-11-22 | Varian Medical Systems, Inc. | System and methods for treating patients using radiation |
US9630025B2 (en) | 2005-07-25 | 2017-04-25 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US10004650B2 (en) | 2005-04-29 | 2018-06-26 | Varian Medical Systems, Inc. | Dynamic patient positioning system |
USRE46953E1 (en) | 2007-04-20 | 2018-07-17 | University Of Maryland, Baltimore | Single-arc dose painting for precision radiation therapy |
US10773101B2 (en) | 2010-06-22 | 2020-09-15 | Varian Medical Systems International Ag | System and method for estimating and manipulating estimated radiation dose |
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US5079426A (en) * | 1989-09-06 | 1992-01-07 | The Regents Of The University Of Michigan | Multi-element-amorphous-silicon-detector-array for real-time imaging and dosimetry of megavoltage photons and diagnostic X rays |
US5081661A (en) * | 1989-09-27 | 1992-01-14 | Siemens Aktiengesellschaft | X-ray examination apparatus |
US5247555A (en) * | 1988-10-28 | 1993-09-21 | Nucletron Manufacturing Corp. | Radiation image generating system and method |
US5335255A (en) * | 1992-03-24 | 1994-08-02 | Seppi Edward J | X-ray scanner with a source emitting plurality of fan beams |
US5825842A (en) * | 1995-07-05 | 1998-10-20 | Kabushiki Kaisha Toshiba | X-ray computed tomographic imaging device and x-ray computed tomographic method |
DE19941149A1 (en) * | 1998-08-31 | 2000-03-02 | Shimadzu Corp | Radiotherapy mapping arrangement, e.g. for cancer; has computer tomographic simulator, X-ray simulator, determination arrangement, superposition and display device |
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US5079426A (en) * | 1989-09-06 | 1992-01-07 | The Regents Of The University Of Michigan | Multi-element-amorphous-silicon-detector-array for real-time imaging and dosimetry of megavoltage photons and diagnostic X rays |
US5081661A (en) * | 1989-09-27 | 1992-01-14 | Siemens Aktiengesellschaft | X-ray examination apparatus |
US5335255A (en) * | 1992-03-24 | 1994-08-02 | Seppi Edward J | X-ray scanner with a source emitting plurality of fan beams |
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Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6865254B2 (en) | 2002-07-02 | 2005-03-08 | Pencilbeam Technologies Ab | Radiation system with inner and outer gantry parts |
WO2004004829A1 (en) * | 2002-07-02 | 2004-01-15 | Pencilbeam Technologies Ab | Radiation system with inner and outer gantry, to enable precise positioning when rotating the inner gantry |
US9901750B2 (en) | 2002-12-18 | 2018-02-27 | Varian Medical Systems, Inc. | Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager |
EP1581804A2 (en) * | 2002-12-18 | 2005-10-05 | Varian Medical Systems Technologies, Inc. | A multi-mode cone beam ct radiotherapy simulator and treatment machine with a flat panel imager |
EP1581804A4 (en) * | 2002-12-18 | 2011-02-23 | Varian Med Sys Inc | A multi-mode cone beam ct radiotherapy simulator and treatment machine with a flat panel imager |
US8116430B1 (en) | 2002-12-18 | 2012-02-14 | Varian Medical Systems, Inc. | Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager |
US8867703B2 (en) | 2002-12-18 | 2014-10-21 | Varian Medical Systems, Inc. | Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager |
US9421399B2 (en) | 2002-12-18 | 2016-08-23 | Varian Medical Systems, Inc. | Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager |
US11344748B2 (en) | 2002-12-18 | 2022-05-31 | Varian Medical Systems, Inc. | Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager |
US9974494B2 (en) | 2005-04-29 | 2018-05-22 | Varian Medical Systems, Inc. | System and methods for treating patients using radiation |
US10004650B2 (en) | 2005-04-29 | 2018-06-26 | Varian Medical Systems, Inc. | Dynamic patient positioning system |
US9498167B2 (en) | 2005-04-29 | 2016-11-22 | Varian Medical Systems, Inc. | System and methods for treating patients using radiation |
US10881878B2 (en) | 2005-04-29 | 2021-01-05 | Varian Medical Systems, Inc. | Dynamic patient positioning system |
US9630025B2 (en) | 2005-07-25 | 2017-04-25 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9687677B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9764159B2 (en) | 2005-07-25 | 2017-09-19 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9788783B2 (en) | 2005-07-25 | 2017-10-17 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9687674B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9687675B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9687673B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US11642027B2 (en) | 2005-07-25 | 2023-05-09 | Siemens Healthineers International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US10595774B2 (en) | 2005-07-25 | 2020-03-24 | Varian Medical Systems International | Methods and apparatus for the planning and delivery of radiation treatments |
US9687678B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
US9687676B2 (en) | 2005-07-25 | 2017-06-27 | Varian Medical Systems International Ag | Methods and apparatus for the planning and delivery of radiation treatments |
USRE46953E1 (en) | 2007-04-20 | 2018-07-17 | University Of Maryland, Baltimore | Single-arc dose painting for precision radiation therapy |
US10773101B2 (en) | 2010-06-22 | 2020-09-15 | Varian Medical Systems International Ag | System and method for estimating and manipulating estimated radiation dose |
US11986671B2 (en) | 2010-06-22 | 2024-05-21 | Siemens Healthineers International Ag | System and method for estimating and manipulating estimated radiation dose |
Also Published As
Publication number | Publication date |
---|---|
GB2366501B (en) | 2002-07-17 |
GB2366501A (en) | 2002-03-06 |
GB0020030D0 (en) | 2000-10-04 |
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