GB2366501A - Radiotherapy simulation apparatus - Google Patents

Radiotherapy simulation apparatus Download PDF

Info

Publication number
GB2366501A
GB2366501A GB0020030A GB0020030A GB2366501A GB 2366501 A GB2366501 A GB 2366501A GB 0020030 A GB0020030 A GB 0020030A GB 0020030 A GB0020030 A GB 0020030A GB 2366501 A GB2366501 A GB 2366501A
Authority
GB
United Kingdom
Prior art keywords
imager
accelerator
simulator
patient
detector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB0020030A
Other versions
GB0020030D0 (en
GB2366501B (en
Inventor
Kevin John Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elekta AB
Original Assignee
Elekta AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elekta AB filed Critical Elekta AB
Priority to GB0020030A priority Critical patent/GB2366501B/en
Publication of GB0020030D0 publication Critical patent/GB0020030D0/en
Priority to PCT/GB2001/003452 priority patent/WO2002013907A1/en
Publication of GB2366501A publication Critical patent/GB2366501A/en
Application granted granted Critical
Publication of GB2366501B publication Critical patent/GB2366501B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4225Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector using image intensifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/44Constructional features of apparatus for radiation diagnosis
    • A61B6/4429Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • A61B6/4435Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
    • A61B6/4441Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure the rigid structure being a C-arm or U-arm

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

A radiotherapy simulator comprises a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome. The accelerator can include an aligned visible light course to assist in patient mark up. The imager is preferable of amorphous silicon. Such imagers are available as flat panel items. It is further preferred that the accelerator and the imager are mounted on opposing arms of a C-shaped support. This provides a simple form of alignment which can be rotated around the patient easily. The imager arm is preferably retractable to allow easy access.

Description

2366501 RADIOTHERAPY SIMULATION APPARATUS The present invention relates to
a radiotherapy apparatus.
In the use of radiotherapy to treat cancer and other ailments, a powerful beam of the appropriate radiation is directed at the area of the patient which is affected. This beam is apt to kill living cells in its path, hence its use against cancerous cells, and therefore it is highly desirable to ensure that the beam is correctly aimed. Failure to do so may result in the unnecessary destruction of healthy cells of the patient.
Several methods are used to check that the alignment of the beam is correct. One such method is a simulator, a low energy source combined with a visible light source. An image can be prepared which corresponds to the therapeutic dose subsequently applied on the full scale accelerator. The visible light source allows the patient to be marked up for subsequent alignment. This form of simulation is suitable for simple treatment plans but is unable to simulate modern complex plans.
Another method is the use of a so-called "portal image". This is an image produced by placing a photographic plate or electronic imaging plate beneath the patient during a brief period of irradiation. The beam is attenuated by the patient's internal organs and structures, leaving an image in the plate. This can then be checked either before complete treatment or after a dose, to ensure that the aim was correct. Portal images are however extremely difficult to interpret as the energy of the beam which is necessary to have a useful therapeutic effect is very much greater than that used for medical imaging. At these higher energies there is smaller ratio in the relative attenuation between bony and tissue structure, which results in portal images with poor contrast. Structures within the patient are difficult to discern.
Another more recent approach is the use of CT simulation. A CT (computerised tomography) scanner is used to scan the patient. From the CT dataset, a digitally reconstructed radiograph (DRR) can be constructed that will be a prediction of the portal image that would be created. The DRR can be set up to enhance the contrast obtained and accordingly avoids the difficulties inherent in the portal image. However, dedicated CT scanners have an aperture limitation which means they cannot simulate the full range of the therapeutic accelerator. Simpler CT scanners based around a simulator can in theory simulate the full therapeutic range, but require a full rotation of the gantry to acquire each CT slice. The available speed of rotation of a simulator gantry means that it is only practical to obtain about 5 slices within a reasonable time. This is sufficient to cater for simple treatment plans but is inadequate for modern 3D treatment planning or Intensity Modulated Radiation Therapy (IMRT) treatment. In addition, CT scanners do not cast an image on the patient which can be used to mark up for later realignment.
Accordingly, there remains a need to provide a practical simulator which can accurately simulate complex treatment plans.
The present invention therefore provides a radiotherapy simulator comprising a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome.
The accelerator can include an aligned visible light course to assist in patient mark-up.
The imager is preferable of amorphous silicon. Such imagers are available as flat panel items.
It is further preferred that the accelerator and the imager are mounted on opposing arms of a C-shaped support. This provides a -simple form of alignment which can be rotated around the patient easily. The imager arm is preferably retractable to allow easy access.
An embodiment of the present invention will now be described by way of example, with reference to the accompanying figure, which shows a schematic view of the system.
As shown in Figure 1, patient 10 is supported on patient table 12. Above the patient is disposed a radiation source 14 capable of producing low energy radiation such as is normally used in simulation. Beneath the patient table 12 lies a planar digital detector 16 on a suitable support arrangement 18. The detector 16 is positioned so as to lie in the path of a beam of radiation 20 that has been omitted by the source 14 and has passed through the patient 10. The output of the detector 16 is fed to a computing apparatus 22.
The radiation source 14 and detector 16 are mounted on the ends of a rotatable C-arm and can therefore be rotated in a corelated fashion around the patient, as shown in dotted lines. The two dimensional nature of the planar detector 16 means that a single rotational scan of the detector and the source will enable multiple slices to be reconstructed via cone beam CT methods. Cone beam reconstruction inherently has the same resolution in all directions and is therefore suited for generation of digitally reconstructed radiographs using the computing apparatus 22. However, the need for a DRR will in many cases be eliminated as the required image will be available directly from the detector, either as a by-product of the rotational scan or as a deliberate imaging action.
The reconstruction process for generation of DRR is complex and therefore dedicated hardware within the computing apparatus is likely to be beneficial in order to reduce the reconstruction time into a period which is effectively on-line. However, it is also possible to generate the image off-line for subsequent use in planning.
A source of optical light can be incorporated within radiation source 14 in order to provide one or more (preferably two or more) reference points for marking up the patient.
Accordingly, the present invention provides a simulator which is able to produce a data set suitable for use in preparation of DRR's and treatment and planning which does not require extended CT scan times. Meanwhile, as opposed to existing scanners, the simulator is sufficiently similar to a treatment apparatus as to provide a reliable simulation process.
It will of course be appreciated that many variations can be made to the above described embodiment without departing from the scope of the present invention.

Claims (4)

1 A radiotherapy simulator comprising a radiation source, a planar digital detector, a patient support table to lie between the accelerator and the imager, and a processing means adapted to interpret the output of the imager to produce a simulated treatment outcome.
2. A simulator according to claim 1 including an aligned visible light source.
3. A simulator according to claim 1 or claim 2 in which the imager is of amorphous silicon.
4. A simulator substantially as described herein with reference to and/or as illustrated in the accompanying figure.
4. A simulator according to any preceding claim in which the accelerator and the imager are mounted on opposing arms of a C-shaped support.
5. A simulator according to claim 4 in which the imager arm is retractable.
6. A simulator substantially as described herein with reference to and/or as illustrated in the accompanying figure.
Amendments to the daims have been riled as follows CLAIMS 1 A radiotherapy simulator comprising a radiation source and a planar digital detector together forming a cone beam CT arrangement, a patient support table lying between the source and the detector, and a processing means adapted to interpret the output of the detector as a cone beam CT image to produce a simulated treatment outcome, in which the accelerator and the imager are mounted on opposing arms of a C-shaped support, at least the imager arm being retractable.
2. A simulator according to claim 1 including an aligned visible light source.
3. A simulator according to claim 1 or claim 2 in which the imager is of amorphous silicon.
GB0020030A 2000-08-16 2000-08-16 Radiotherapy simulation apparatus Expired - Fee Related GB2366501B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0020030A GB2366501B (en) 2000-08-16 2000-08-16 Radiotherapy simulation apparatus
PCT/GB2001/003452 WO2002013907A1 (en) 2000-08-16 2001-07-31 Radiotherapy simulation apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0020030A GB2366501B (en) 2000-08-16 2000-08-16 Radiotherapy simulation apparatus

Publications (3)

Publication Number Publication Date
GB0020030D0 GB0020030D0 (en) 2000-10-04
GB2366501A true GB2366501A (en) 2002-03-06
GB2366501B GB2366501B (en) 2002-07-17

Family

ID=9897610

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0020030A Expired - Fee Related GB2366501B (en) 2000-08-16 2000-08-16 Radiotherapy simulation apparatus

Country Status (2)

Country Link
GB (1) GB2366501B (en)
WO (1) WO2002013907A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6865254B2 (en) * 2002-07-02 2005-03-08 Pencilbeam Technologies Ab Radiation system with inner and outer gantry parts
US7945021B2 (en) 2002-12-18 2011-05-17 Varian Medical Systems, Inc. Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager
US20070003010A1 (en) 2005-04-29 2007-01-04 Varian Medical Systems Technologies, Inc. Radiation systems with imaging capability
US7880154B2 (en) 2005-07-25 2011-02-01 Karl Otto Methods and apparatus for the planning and delivery of radiation treatments
EP2088925B8 (en) 2006-11-17 2015-06-17 Varian Medical Systems, Inc. Dynamic patient positioning system
USRE46953E1 (en) 2007-04-20 2018-07-17 University Of Maryland, Baltimore Single-arc dose painting for precision radiation therapy
US9289627B2 (en) 2010-06-22 2016-03-22 Varian Medical Systems International Ag System and method for estimating and manipulating estimated radiation dose

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187895A (en) * 1967-08-10 1970-04-15 Ca Atomic Energy Ltd Automatic Positioning Apparatus for Irradiation.
GB1572347A (en) * 1976-03-30 1980-07-30 Emi Ltd Radiographic apparatus
US5014290A (en) * 1988-10-28 1991-05-07 Moore Robert M Method and apparatus for generating radiation blockers
GB2293917A (en) * 1994-10-06 1996-04-10 Varian Associates Radiotherapy apparatus with x-ray imaging
JPH1043320A (en) * 1996-07-31 1998-02-17 Shimadzu Corp Simulator system for radiation therapy plan
EP0489904B1 (en) * 1990-07-02 1998-03-04 Varian Associates, Inc. Radiation therapy x-ray simulator
US5754623A (en) * 1994-03-25 1998-05-19 Kabushiki Kaisha Toshiba Radiotherapy system
US5901199A (en) * 1996-07-11 1999-05-04 The Board Of Trustees Of The Leland Stanford Junior University High-speed inter-modality image registration via iterative feature matching
JP2000051194A (en) * 1998-08-10 2000-02-22 Toshiba Corp Radiation ct system
US6101236A (en) * 1998-10-02 2000-08-08 University Of Iowa Research Foundation Iterative method and apparatus for x-ray computed tomographic fluoroscopy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5247555A (en) * 1988-10-28 1993-09-21 Nucletron Manufacturing Corp. Radiation image generating system and method
EP0490997A4 (en) * 1989-09-06 1993-01-27 The University Of Michigan, Intellectual Property Office Multi-element-amorphous-silicon-detector-array for real-time imaging and dosimetry of megavoltage photons and diagnostic x-rays
SE8903175D0 (en) * 1989-09-27 1989-09-27 Siemens Elema Ab DEVICE FOR X-ray examinations
US5335255A (en) * 1992-03-24 1994-08-02 Seppi Edward J X-ray scanner with a source emitting plurality of fan beams
JP2914891B2 (en) * 1995-07-05 1999-07-05 株式会社東芝 X-ray computed tomography apparatus
JP4354550B2 (en) * 1998-08-31 2009-10-28 株式会社島津製作所 Radiation therapy planning device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1187895A (en) * 1967-08-10 1970-04-15 Ca Atomic Energy Ltd Automatic Positioning Apparatus for Irradiation.
GB1572347A (en) * 1976-03-30 1980-07-30 Emi Ltd Radiographic apparatus
US5014290A (en) * 1988-10-28 1991-05-07 Moore Robert M Method and apparatus for generating radiation blockers
EP0489904B1 (en) * 1990-07-02 1998-03-04 Varian Associates, Inc. Radiation therapy x-ray simulator
US5754623A (en) * 1994-03-25 1998-05-19 Kabushiki Kaisha Toshiba Radiotherapy system
GB2293917A (en) * 1994-10-06 1996-04-10 Varian Associates Radiotherapy apparatus with x-ray imaging
US5901199A (en) * 1996-07-11 1999-05-04 The Board Of Trustees Of The Leland Stanford Junior University High-speed inter-modality image registration via iterative feature matching
JPH1043320A (en) * 1996-07-31 1998-02-17 Shimadzu Corp Simulator system for radiation therapy plan
JP2000051194A (en) * 1998-08-10 2000-02-22 Toshiba Corp Radiation ct system
US6101236A (en) * 1998-10-02 2000-08-08 University Of Iowa Research Foundation Iterative method and apparatus for x-ray computed tomographic fluoroscopy

Also Published As

Publication number Publication date
GB0020030D0 (en) 2000-10-04
GB2366501B (en) 2002-07-17
WO2002013907A1 (en) 2002-02-21

Similar Documents

Publication Publication Date Title
US11737714B2 (en) Cone-beam computed tomography imaging devices, systems, and methods
US11344748B2 (en) Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager
US7453976B1 (en) Computerized tomography image reconstruction
JP4271941B2 (en) Method for enhancing a tomographic projection image of a patient
Jaffray et al. Flat-panel cone-beam computed tomography for image-guided radiation therapy
US5117829A (en) Patient alignment system and procedure for radiation treatment
US20070291895A1 (en) Systems and methods for localizing a target for radiotherapy based on digital tomosynthesis
JP4354550B2 (en) Radiation therapy planning device
Sillanpaa et al. Developments in megavoltage cone beam CT with an amorphous silicon EPID: reduction of exposure and synchronization with respiratory gating
Swinnen et al. The potential of an optical surface tracking system in non‐coplanar single isocenter treatments of multiple brain metastases
Lu et al. A comprehensive study on decreasing the kilovoltage cone‐beam CT dose by reducing the projection number
EP1572298B1 (en) Radiotherapy apparatus
Wu et al. On-board patient positioning for head-and-neck IMRT: comparing digital tomosynthesis to kilovoltage radiography and cone-beam computed tomography
US9474913B2 (en) Universal teletherapy treatment room arrangement
GB2366501A (en) Radiotherapy simulation apparatus
Ali et al. Evaluation of the effects of sagging shifts on isocenter accuracy and image quality of cone‐beam CT from kV on‐board imagers
Nakagawa et al. Technological features and clinical feasibility of megavoltage CT scanning
Zhao et al. The clinical feasibility and effect of online ExacTrac 6 degree-of-freedom system for head-and-neck cancer
Zhang et al. Tomographic image via background subtraction using an x‐ray projection image and a priori computed tomography
Ung Uncertainties in prostate targeting during radiotherapy: assessment, implications and applications of statistical methods of process control

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20040816