WO2002012335A3 - A NEW EGF MOTIF REPEAT PROTEIN OBTAINED FROM A cDNA LIBRARY FROM HS-5 STROMAL CELL LINE - Google Patents

A NEW EGF MOTIF REPEAT PROTEIN OBTAINED FROM A cDNA LIBRARY FROM HS-5 STROMAL CELL LINE Download PDF

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Publication number
WO2002012335A3
WO2002012335A3 PCT/US2001/025282 US0125282W WO0212335A3 WO 2002012335 A3 WO2002012335 A3 WO 2002012335A3 US 0125282 W US0125282 W US 0125282W WO 0212335 A3 WO0212335 A3 WO 0212335A3
Authority
WO
WIPO (PCT)
Prior art keywords
repeat protein
egf motif
cell line
motif repeat
cdna library
Prior art date
Application number
PCT/US2001/025282
Other languages
French (fr)
Other versions
WO2002012335A2 (en
Inventor
Parul D Doshi
Martin F Meier
Cynthia L Woods
Original Assignee
Pharmacia Corp
Parul D Doshi
Martin F Meier
Cynthia L Woods
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp, Parul D Doshi, Martin F Meier, Cynthia L Woods filed Critical Pharmacia Corp
Priority to AU2001281254A priority Critical patent/AU2001281254A1/en
Publication of WO2002012335A2 publication Critical patent/WO2002012335A2/en
Publication of WO2002012335A3 publication Critical patent/WO2002012335A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a new EGF motif repeat protein obtained from a cDNA library from HS-5 stromal cell line, nucleic acid molecules that encode the EGF motif repeat protein or a fragment thereof and nucleic acid molecules that are useful as probes or primers for detecting or amplifying the EGF motif repeat protein, respectively. The invention further relates to uses of the EGF motif repeat protein. The invention also relates to applications of the factor or fragment such as forming antibodies capable of binding the factor or fragments thereof.
PCT/US2001/025282 2000-08-10 2001-08-10 A NEW EGF MOTIF REPEAT PROTEIN OBTAINED FROM A cDNA LIBRARY FROM HS-5 STROMAL CELL LINE WO2002012335A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281254A AU2001281254A1 (en) 2000-08-10 2001-08-10 A new egf motif repeat protein obtained from a cdna library from hs-5 stromal cell line

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63647400A 2000-08-10 2000-08-10
US09/636,474 2000-08-10

Publications (2)

Publication Number Publication Date
WO2002012335A2 WO2002012335A2 (en) 2002-02-14
WO2002012335A3 true WO2002012335A3 (en) 2003-08-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025282 WO2002012335A2 (en) 2000-08-10 2001-08-10 A NEW EGF MOTIF REPEAT PROTEIN OBTAINED FROM A cDNA LIBRARY FROM HS-5 STROMAL CELL LINE

Country Status (2)

Country Link
AU (1) AU2001281254A1 (en)
WO (1) WO2002012335A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23526B6 (en) 2006-10-03 2010-05-19 Ct Ingenieria Genetica Biotech METHOD FOR MORFOFUNCTIONAL RESTORATION OF PERIPHERAL NERVES IN DIABETIC NEUROPATHY

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002662A1 (en) * 1994-07-20 1996-02-01 Fred Hutchinson Cancer Research Center Human marrow stromal cell lines which sustain hematopoiesis
JPH1036395A (en) * 1996-07-24 1998-02-10 Asahi Chem Ind Co Ltd New membrane protein
WO1998056804A1 (en) * 1997-06-13 1998-12-17 Human Genome Sciences, Inc. 86 human secreted proteins
WO1999027096A1 (en) * 1997-11-22 1999-06-03 Hyseq, Inc. A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN
WO1999028462A2 (en) * 1997-12-03 1999-06-10 Genentech, Inc. Polypeptides and nucleic acids encoding the same
WO2000017357A1 (en) * 1998-09-18 2000-03-30 Hyseq, Inc. Methods and compositions relating to egf-repeat-containing polypeptides
WO2000032776A2 (en) * 1998-12-01 2000-06-08 Genentech, Inc. Secreted amd transmembrane polypeptides and nucleic acids encoding the same

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996002662A1 (en) * 1994-07-20 1996-02-01 Fred Hutchinson Cancer Research Center Human marrow stromal cell lines which sustain hematopoiesis
JPH1036395A (en) * 1996-07-24 1998-02-10 Asahi Chem Ind Co Ltd New membrane protein
WO1998056804A1 (en) * 1997-06-13 1998-12-17 Human Genome Sciences, Inc. 86 human secreted proteins
WO1999027096A1 (en) * 1997-11-22 1999-06-03 Hyseq, Inc. A NOVEL EGF MOTIF PROTEIN OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN
WO1999028462A2 (en) * 1997-12-03 1999-06-10 Genentech, Inc. Polypeptides and nucleic acids encoding the same
WO2000017357A1 (en) * 1998-09-18 2000-03-30 Hyseq, Inc. Methods and compositions relating to egf-repeat-containing polypeptides
WO2000032776A2 (en) * 1998-12-01 2000-06-08 Genentech, Inc. Secreted amd transmembrane polypeptides and nucleic acids encoding the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199816, Derwent World Patents Index; Class B04, AN 1998-174912, XP002217927 *
MILNER LAURIE A ET AL: "Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation.", BLOOD, vol. 93, no. 8, 15 April 1999 (1999-04-15), pages 2431 - 2448, XP002217926, ISSN: 0006-4971 *

Also Published As

Publication number Publication date
WO2002012335A2 (en) 2002-02-14
AU2001281254A1 (en) 2002-02-18

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