WO2002010387A3 - G-protein coupled receptors - Google Patents

G-protein coupled receptors Download PDF

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Publication number
WO2002010387A3
WO2002010387A3 PCT/US2001/023433 US0123433W WO0210387A3 WO 2002010387 A3 WO2002010387 A3 WO 2002010387A3 US 0123433 W US0123433 W US 0123433W WO 0210387 A3 WO0210387 A3 WO 0210387A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein coupled
coupled receptors
gcrec
provides
mehtods
Prior art date
Application number
PCT/US2001/023433
Other languages
French (fr)
Other versions
WO2002010387A2 (en
Inventor
Michael Thornton
Chandra Arvizu
Preeti Lal
Neil Burford
Henry Yue
Ameena R Gandhi
Vicki S Elliot
Jayalaxmi Ramkumar
Mariah R Baughn
Deborah A Kallick
Narinder K Walia
April J A Hafalia
Monique G Yao
Yan Lu
Catherine M Tribouley
Jennifer L Policky
Liam Kearney
Richard C Graul
Bridget A Warren
Ernestine A Lee
Li Ding
Original Assignee
Incyte Genomics Inc
Michael Thornton
Chandra Arvizu
Preeti Lal
Neil Burford
Henry Yue
Ameena R Gandhi
Vicki S Elliot
Jayalaxmi Ramkumar
Mariah R Baughn
Deborah A Kallick
Narinder K Walia
April J A Hafalia
Monique G Yao
Yan Lu
Catherine M Tribouley
Jennifer L Policky
Liam Kearney
Richard C Graul
Bridget A Warren
Ernestine A Lee
Li Ding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Michael Thornton, Chandra Arvizu, Preeti Lal, Neil Burford, Henry Yue, Ameena R Gandhi, Vicki S Elliot, Jayalaxmi Ramkumar, Mariah R Baughn, Deborah A Kallick, Narinder K Walia, April J A Hafalia, Monique G Yao, Yan Lu, Catherine M Tribouley, Jennifer L Policky, Liam Kearney, Richard C Graul, Bridget A Warren, Ernestine A Lee, Li Ding filed Critical Incyte Genomics Inc
Priority to CA002417195A priority Critical patent/CA2417195A1/en
Priority to US10/333,946 priority patent/US20040023252A1/en
Priority to AU2001280785A priority patent/AU2001280785A1/en
Priority to JP2002516303A priority patent/JP2004516817A/en
Priority to EP01959203A priority patent/EP1303609A2/en
Publication of WO2002010387A2 publication Critical patent/WO2002010387A2/en
Publication of WO2002010387A3 publication Critical patent/WO2002010387A3/en

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    • GPHYSICS
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
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    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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Abstract

The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonist, and antagonist. The invention also provides mehtods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
PCT/US2001/023433 2000-07-27 2001-07-25 G-protein coupled receptors WO2002010387A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002417195A CA2417195A1 (en) 2000-07-27 2001-07-25 G-protein coupled receptors
US10/333,946 US20040023252A1 (en) 2001-07-25 2001-07-25 G-protein coupled receptors
AU2001280785A AU2001280785A1 (en) 2000-07-27 2001-07-25 G-protein coupled receptors
JP2002516303A JP2004516817A (en) 2000-07-27 2001-07-25 G protein-coupled receptor
EP01959203A EP1303609A2 (en) 2000-07-27 2001-07-25 G-protein coupled receptors

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US22147800P 2000-07-27 2000-07-27
US60/221,478 2000-07-27
US22326800P 2000-08-03 2000-08-03
US60/223,268 2000-08-03
US22705400P 2000-08-21 2000-08-21
US60/227,054 2000-08-21
US23112100P 2000-09-08 2000-09-08
US60/231,121 2000-09-08
US23224300P 2000-09-13 2000-09-13
US60/232,243 2000-09-13
US23269100P 2000-09-15 2000-09-15
US60/232,691 2000-09-15
US23514600P 2000-09-22 2000-09-22
US60/235,146 2000-09-22

Publications (2)

Publication Number Publication Date
WO2002010387A2 WO2002010387A2 (en) 2002-02-07
WO2002010387A3 true WO2002010387A3 (en) 2003-01-03

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ID=27569369

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Application Number Title Priority Date Filing Date
PCT/US2001/023433 WO2002010387A2 (en) 2000-07-27 2001-07-25 G-protein coupled receptors

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JP (1) JP2004516817A (en)
AU (1) AU2001280785A1 (en)
CA (1) CA2417195A1 (en)
WO (1) WO2002010387A2 (en)

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US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
GB2371546A (en) * 2000-09-12 2002-07-31 Smithkline Beecham Corp G protein coupled receptor AXOR 109
AU2002212309A1 (en) * 2000-10-06 2002-04-15 Bayer Aktiengesellschaft Regulation of human secretin receptor-like gpcr
MXPA03003902A (en) 2000-11-03 2004-04-02 Univ California Prokineticin polypeptides, related compositions and methods.
GB0027537D0 (en) * 2000-11-10 2000-12-27 Glaxo Group Ltd New polypeptide
EP1347052B1 (en) * 2000-11-17 2010-05-05 Banyu Pharmaceutical Co., Ltd. A method for screening compouneds using the guanosine triphosphate (gtp) binding protein-coupled receptor protein, bg37
AU2002228002A1 (en) * 2000-12-14 2002-06-24 Bayer Aktiengesellschaft Regulation of human chemokine-like receptor
AU2002258780A1 (en) 2001-04-11 2002-10-28 Bristol-Myers Squibb Company Polynucleotides encoding two novel human g-protein coupled receptors, hgprbmy28 and hgprbmy29, and splice variants thereof
EP1382678B1 (en) * 2001-04-25 2008-08-27 Astellas Pharma Inc. Guanosine triphosphate-binding protein-coupled recepotr place 6002312 and its gene and production and use of the same
US20030143668A1 (en) * 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors
WO2003027142A1 (en) * 2001-09-21 2003-04-03 Yamanouchi Pharmaceutical Co., Ltd. Novel g protein-coupled receptor
GB0208407D0 (en) 2001-10-01 2002-05-22 Aventis Pharma Inc A novel G protein-coupled receptor, GAVE10
AU2002364149A1 (en) * 2001-12-06 2003-06-23 Bristol-Myers Squibb Company Novel human g-protein coupled receptor, hgprbmy34, and variants and methods of use thereof
WO2004029086A2 (en) * 2002-09-25 2004-04-08 Bayer Healthcare Ag Regulation of human calcium-independent alpha-latrotoxin receptor homolog 3
AU2003279308A1 (en) * 2002-11-04 2004-06-07 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 73a (gpr73a)
WO2005059550A1 (en) * 2003-10-06 2005-06-30 H. Lundbeck A/S Dna encoding snorf138 and uses thereof

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