WO2002008260A3 - Bstp-ecg1 protein and related reagents and methods of use thereof - Google Patents

Bstp-ecg1 protein and related reagents and methods of use thereof Download PDF

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Publication number
WO2002008260A3
WO2002008260A3 PCT/US2001/023439 US0123439W WO0208260A3 WO 2002008260 A3 WO2002008260 A3 WO 2002008260A3 US 0123439 W US0123439 W US 0123439W WO 0208260 A3 WO0208260 A3 WO 0208260A3
Authority
WO
WIPO (PCT)
Prior art keywords
ecg1
bstp
methods
provides
protein
Prior art date
Application number
PCT/US2001/023439
Other languages
French (fr)
Other versions
WO2002008260A9 (en
WO2002008260A2 (en
Inventor
David Botstein
Patrick O Brown
Chuck Perou
Douglas Ross
Rob Seitz
Original Assignee
Univ Stanford
Applied Genomics Inc
David Botstein
Patrick O Brown
Chuck Perou
Douglas Ross
Rob Seitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Stanford, Applied Genomics Inc, David Botstein, Patrick O Brown, Chuck Perou, Douglas Ross, Rob Seitz filed Critical Univ Stanford
Priority to AU2001278011A priority Critical patent/AU2001278011A1/en
Publication of WO2002008260A2 publication Critical patent/WO2002008260A2/en
Publication of WO2002008260A3 publication Critical patent/WO2002008260A3/en
Publication of WO2002008260A9 publication Critical patent/WO2002008260A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention provides polypeptides (BSTP-ECG1) and polynucleotides which identify and encode BSTP-ECG1 and fragments and variants thereof. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. In addition, the invention provides methods for treating or preventing disorders of cell proliferation, particularly breast cancer, by administering a pharmaceutical composition comprising a polypeptide, polynucleotide, or antibody of the invention. The invention also provides methods of classifying diseases, particularly breast cancer, by detecting expression of BSTP-ECG1 or of a polynucleotide encoding BSTP-ECG1, and of providing diagnostic, prognostic, and/or predictive information for a patient based on the detection and/or measurement of BSTP-ECG1 or of a polynucleotide encoding BSTP-ECG1.
PCT/US2001/023439 2000-07-26 2001-07-26 Bstp-ecg1 protein and related reagents and methods of use thereof WO2002008260A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001278011A AU2001278011A1 (en) 2000-07-26 2001-07-26 Bstp-ecg1 protein and related reagents and methods of use thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22096700P 2000-07-26 2000-07-26
US60/220,967 2000-07-26
US25166900P 2000-12-06 2000-12-06
US60/251,669 2000-12-06

Publications (3)

Publication Number Publication Date
WO2002008260A2 WO2002008260A2 (en) 2002-01-31
WO2002008260A3 true WO2002008260A3 (en) 2002-10-17
WO2002008260A9 WO2002008260A9 (en) 2003-03-20

Family

ID=26915369

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/023439 WO2002008260A2 (en) 2000-07-26 2001-07-26 Bstp-ecg1 protein and related reagents and methods of use thereof

Country Status (2)

Country Link
AU (1) AU2001278011A1 (en)
WO (1) WO2002008260A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110489660A (en) * 2019-07-22 2019-11-22 武汉大学 A kind of user's economic situation portrait method of social media public data

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* Cited by examiner, † Cited by third party
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DK2799555T3 (en) 2002-03-13 2017-05-22 Genomic Health Inc Gene Expression Profiling in Tumor Tissue Biopsies
CA2506066A1 (en) 2002-11-15 2004-06-03 Genomic Health, Inc. Gene expression profiling of egfr positive cancer
US20040231909A1 (en) 2003-01-15 2004-11-25 Tai-Yang Luh Motorized vehicle having forward and backward differential structure
PT1597391E (en) 2003-02-20 2008-12-19 Genomic Health Inc Use of intronic rna to measure gene expression
US20040185559A1 (en) 2003-03-21 2004-09-23 Isis Pharmaceuticals Inc. Modulation of diacylglycerol acyltransferase 1 expression
CA2530738C (en) 2003-06-24 2020-01-21 Genomic Health, Inc. Prediction of likelihood of cancer recurrence
CA2531967C (en) 2003-07-10 2013-07-16 Genomic Health, Inc. Expression profile algorithm and test for cancer prognosis
US7825235B2 (en) 2003-08-18 2010-11-02 Isis Pharmaceuticals, Inc. Modulation of diacylglycerol acyltransferase 2 expression
WO2005064019A2 (en) 2003-12-23 2005-07-14 Genomic Health, Inc. Universal amplification of fragmented rna
AU2005233593B2 (en) 2004-04-09 2010-08-26 Fondazione Irccs Istituto Nazionale Dei Tumori Gene expression markers for predicting response to chemotherapy
US7587279B2 (en) 2004-07-06 2009-09-08 Genomic Health Method for quantitative PCR data analysis system (QDAS)
US7622251B2 (en) 2004-11-05 2009-11-24 Genomic Health, Inc. Molecular indicators of breast cancer prognosis and prediction of treatment response
PL1836629T3 (en) 2004-11-05 2020-06-15 Genomic Health, Inc. Predicting response to chemotherapy using gene expression markers
EP2016247A4 (en) 2006-05-08 2013-07-17 Canimex Inc Brake device with integrated anti-theft mechanism for garage doors and the like, and door assembly including the same
US8003620B2 (en) 2006-08-04 2011-08-23 Isis Pharmaceuticals, Inc. Compositions and their uses directed to diacylglycerol acyltransferase 1
DK3320094T3 (en) 2015-07-10 2022-05-23 Ionis Pharmaceuticals Inc MODULATORS OF DIACYGLYCEROL ACYLTRANSFERASE 2 (DGAT2)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999044063A2 (en) * 1998-02-25 1999-09-02 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
WO1999047655A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid fragments with heightened expression in normal breast tissue
WO2000012708A2 (en) * 1998-09-01 2000-03-09 Genentech, Inc. Further pro polypeptides and sequences thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999044063A2 (en) * 1998-02-25 1999-09-02 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
WO1999047655A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid fragments with heightened expression in normal breast tissue
WO2000012708A2 (en) * 1998-09-01 2000-03-09 Genentech, Inc. Further pro polypeptides and sequences thereof

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CASES S. ET AL.: "Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 42, 19 October 2001 (2001-10-19), October 19, 2001, pages 38870 - 38876, XP002199715, ISSN: 0021-9258 *
GOLUB T. R. ET AL.: "MOLECULAR CLASSIFICATION OF CANCER: CLASS DISCOVERY AND CLASS PREDICTION BY GENE EXPRESSION MONITORING", SCIENCE, vol. 286, 15 October 1999 (1999-10-15), pages 531 - 537, XP002905479, ISSN: 0036-8075 *
MARTIN K. J. ET AL.: "LINKING GENE EXPRESSION PATTERNS TO THERAPEUTIC GROUPS IN BREAST CANCER", CANCER RESEARCH, vol. 60, no. 8, 15 April 2000 (2000-04-15), pages 2232 - 2238, XP001026395, ISSN: 0008-5472 *
MENDOZA L. G. ET AL.: "HIGH-THROUGHPUT MICROARRAY-BASED ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA)", BIOTECHNIQUES, vol. 27, no. 4, October 1999 (1999-10-01), pages 778,780,782 - 786,788, XP000992893, ISSN: 0736-6205 *
NACHT M. ET AL.: "Combining serial analysis of gene expression and array technologies to identify genes differentially expressed in breast cancer", CANCER RESEARCH, vol. 59, no. 21, 1 November 1999 (1999-11-01), pages 5464 - 5470, XP002166291, ISSN: 0008-5472 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110489660A (en) * 2019-07-22 2019-11-22 武汉大学 A kind of user's economic situation portrait method of social media public data
CN110489660B (en) * 2019-07-22 2020-12-18 武汉大学 User economic condition portrait method of social media public data

Also Published As

Publication number Publication date
AU2001278011A1 (en) 2002-02-05
WO2002008260A9 (en) 2003-03-20
WO2002008260A2 (en) 2002-01-31

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