WO2002005862A8 - Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten - Google Patents

Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten

Info

Publication number
WO2002005862A8
WO2002005862A8 PCT/EP2000/006838 EP0006838W WO0205862A8 WO 2002005862 A8 WO2002005862 A8 WO 2002005862A8 EP 0006838 W EP0006838 W EP 0006838W WO 0205862 A8 WO0205862 A8 WO 0205862A8
Authority
WO
WIPO (PCT)
Prior art keywords
implants
calcium phosphate
composite layers
electrochemically deposited
phosphate composite
Prior art date
Application number
PCT/EP2000/006838
Other languages
English (en)
French (fr)
Other versions
WO2002005862A1 (de
Inventor
Hans-Georg Neumann
Peter Zeggel
Petra Becker
Original Assignee
Dot Gmbh
Neumann Hans Georg
Peter Zeggel
Petra Becker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dot Gmbh, Neumann Hans Georg, Peter Zeggel, Petra Becker filed Critical Dot Gmbh
Priority to CA002416201A priority Critical patent/CA2416201C/en
Priority to PCT/EP2000/006838 priority patent/WO2002005862A1/de
Priority to EP00945927A priority patent/EP1301220A1/de
Priority to AU2000259855A priority patent/AU2000259855B2/en
Priority to AU5985500A priority patent/AU5985500A/xx
Priority to JP2002511793A priority patent/JP2004503333A/ja
Publication of WO2002005862A1 publication Critical patent/WO2002005862A1/de
Publication of WO2002005862A8 publication Critical patent/WO2002005862A8/de
Priority to HK04103012A priority patent/HK1060070A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

Die Erfindung betrifft elektrochemisch abgeschiedene Calciumphosphat-Kompositschichten auf Knochenimplantaten. Derart beschichtete Implantate werden zementfrei implantiert und zeichnen sich durch ein verbessertes Einwachsverhalten aus. Die zur Erfinding angemeldeten hochporösen Kompositschichten auf Implantaten bestehen aus zwei oder mehreren Calciumphosphat-Phasen unterschiedlicher Löslichkeit. Die hochporöse Struktur dieser Schichten erleichtert die Immobilisierung von Zellen, von denen ausgehend sich neues Knochengewebe bilden kann. Die unterschiedliche Löslichkeit der einzelnen Schichtkomponenten gewährleistet die den Einheilungsprozess beschleunigende und im zeitlichen Verlauf an diesen Prozess angepasste lokale Konzentration an Calcium- und Phosphationen.
PCT/EP2000/006838 2000-07-17 2000-07-17 Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten WO2002005862A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA002416201A CA2416201C (en) 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants
PCT/EP2000/006838 WO2002005862A1 (de) 2000-07-17 2000-07-17 Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten
EP00945927A EP1301220A1 (de) 2000-07-17 2000-07-17 Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten
AU2000259855A AU2000259855B2 (en) 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants
AU5985500A AU5985500A (en) 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants
JP2002511793A JP2004503333A (ja) 2000-07-17 2000-07-17 インプラントに電気化学的に析着される生体活性リン酸カルシウム複合層及びその製造方法
HK04103012A HK1060070A1 (en) 2000-07-17 2004-04-29 Bioactive calcium phosphate composite layers electrochemically deposited on implants.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2000/006838 WO2002005862A1 (de) 2000-07-17 2000-07-17 Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten

Publications (2)

Publication Number Publication Date
WO2002005862A1 WO2002005862A1 (de) 2002-01-24
WO2002005862A8 true WO2002005862A8 (de) 2002-05-30

Family

ID=8164028

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/006838 WO2002005862A1 (de) 2000-07-17 2000-07-17 Elektrochemisch abgeschiedene, bioaktive calciumphosphat-kompositschichten auf implantaten

Country Status (6)

Country Link
EP (1) EP1301220A1 (de)
JP (1) JP2004503333A (de)
AU (2) AU5985500A (de)
CA (1) CA2416201C (de)
HK (1) HK1060070A1 (de)
WO (1) WO2002005862A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007730A1 (en) * 2004-07-21 2006-01-26 The University Of British Columbia Method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant
US11278642B2 (en) 2006-09-08 2022-03-22 Takao Hotokebuchi Bioimplant with evanescent coating film
US10610614B2 (en) 2006-09-08 2020-04-07 Kyocera Corporation Bioimplant with evanescent coating film
WO2008029612A1 (fr) * 2006-09-08 2008-03-13 Japan Medical Materials Corporation Bio-implant
DE102012001260B4 (de) * 2012-01-23 2015-04-02 Dot Gmbh Antibakterielle und osteoinduktive Implantatbeschichtung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
DE19504386C2 (de) * 1995-02-10 1997-08-28 Univ Dresden Tech Verfahren zur Herstellung einer gradierten Beschichtung aus Calciumphosphatphasen und Metalloxidphasen auf metallischen Implantaten
EP0806212B1 (de) * 1996-05-10 2003-04-02 IsoTis N.V. Vorrichtung zur Aufnahme und Freigabe von biologisch aktiven Substanzen
US6045683A (en) * 1997-12-01 2000-04-04 University Of Alabama In Huntsville Modified brushite surface coating, process therefor, and low temperature conversion to hydroxyapatite
AU766735B2 (en) * 1998-09-15 2003-10-23 Isotis N.V. Osteoinduction

Also Published As

Publication number Publication date
AU2000259855B2 (en) 2006-02-02
WO2002005862A1 (de) 2002-01-24
CA2416201A1 (en) 2003-01-15
HK1060070A1 (en) 2004-07-30
AU5985500A (en) 2002-01-30
CA2416201C (en) 2008-11-18
EP1301220A1 (de) 2003-04-16
JP2004503333A (ja) 2004-02-05
AU2000259855A1 (en) 2002-05-02

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