WO2002002580A3 - Haplotypes of the etfb gene - Google Patents

Haplotypes of the etfb gene Download PDF

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Publication number
WO2002002580A3
WO2002002580A3 PCT/US2001/021306 US0121306W WO0202580A3 WO 2002002580 A3 WO2002002580 A3 WO 2002002580A3 US 0121306 W US0121306 W US 0121306W WO 0202580 A3 WO0202580 A3 WO 0202580A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
etfb
gene
disclosed
etfb gene
Prior art date
Application number
PCT/US2001/021306
Other languages
French (fr)
Other versions
WO2002002580A2 (en
Inventor
Steven C Bentivegna
Karyn M Bieglecki
Amir Kazemi
Beena Koshy
Original Assignee
Genaissance Pharmaceuticals
Steven C Bentivegna
Karyn M Bieglecki
Amir Kazemi
Beena Koshy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Steven C Bentivegna, Karyn M Bieglecki, Amir Kazemi, Beena Koshy filed Critical Genaissance Pharmaceuticals
Priority to AU2001280483A priority Critical patent/AU2001280483A1/en
Publication of WO2002002580A2 publication Critical patent/WO2002002580A2/en
Publication of WO2002002580A3 publication Critical patent/WO2002002580A3/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel genetic variants of the Electron-Transfer-Flavoprotein, Beta Polypeptide (ETFB) gene are described. Various genotypes, haplotypes, and haplotype pairs that exist in the general United States population are disclosed for the ETFB gene. Compositions and methods for haplotyping and/or genotyping the ETFB gene in an individual are also disclosed. Polynucleotides defined by the haplotypes disclosed herein are also described.
PCT/US2001/021306 2000-07-05 2001-07-05 Haplotypes of the etfb gene WO2002002580A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001280483A AU2001280483A1 (en) 2000-07-05 2001-07-05 Haplotypes of the etfb gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21598400P 2000-07-05 2000-07-05
US60/215,984 2000-07-05

Publications (2)

Publication Number Publication Date
WO2002002580A2 WO2002002580A2 (en) 2002-01-10
WO2002002580A3 true WO2002002580A3 (en) 2002-06-20

Family

ID=22805184

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/021306 WO2002002580A2 (en) 2000-07-05 2001-07-05 Haplotypes of the etfb gene

Country Status (2)

Country Link
AU (1) AU2001280483A1 (en)
WO (1) WO2002002580A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102477429A (en) * 2011-11-25 2012-05-30 浙江海洋学院 Scylla paramamosain ETFB gene and clone, detection method and application thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COLOMBO I. ET AL.: "Mutations and polymorphisms of the gene encoding the beta-subunit of the electron transfer flavoprotein in three patients with glutaric acidemia type II", HUMAN MOLECULAR GENETICS, vol. 3, 1994, pages 429 - 435, XP002906429 *
FINOCCHIARO G. ET AL.: "cDNA cloning and mitochondrial import of the beta-subunit of the human electron-transfer flavoprotein", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 213, 1993, pages 1003 - 1008, XP002906430 *
ROYAL V. ET AL.: "RsaI RFLP for electron transport flavoprotein-beta (ETFB)", NUCLEIC ACIDS RESEARCH, vol. 19, 1991, pages 4021, XP002906428 *

Also Published As

Publication number Publication date
AU2001280483A1 (en) 2002-01-14
WO2002002580A2 (en) 2002-01-10

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