WO2001084146B1 - Biocapteur multiplex sensible a spectrometrie de masse base sur l'immuno-pcr - Google Patents
Biocapteur multiplex sensible a spectrometrie de masse base sur l'immuno-pcrInfo
- Publication number
- WO2001084146B1 WO2001084146B1 PCT/IB2001/000957 IB0100957W WO0184146B1 WO 2001084146 B1 WO2001084146 B1 WO 2001084146B1 IB 0100957 W IB0100957 W IB 0100957W WO 0184146 B1 WO0184146 B1 WO 0184146B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antibody
- spectrometry
- immuno
- pcr
- sensitive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001258700A AU2001258700A1 (en) | 2000-05-04 | 2001-05-04 | A sensitive, multiplexed mass-spectrometry-based biosensor based on immuno-pcr |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0001670A SE0001670D0 (sv) | 2000-05-04 | 2000-05-04 | Mass-spectrometry-based biosensor |
SE0001670-9 | 2000-05-04 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2001084146A2 WO2001084146A2 (fr) | 2001-11-08 |
WO2001084146A3 WO2001084146A3 (fr) | 2002-04-11 |
WO2001084146B1 true WO2001084146B1 (fr) | 2002-07-04 |
Family
ID=20279569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2001/000957 WO2001084146A2 (fr) | 2000-05-04 | 2001-05-04 | Biocapteur multiplex sensible a spectrometrie de masse base sur l'immuno-pcr |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2001258700A1 (fr) |
SE (1) | SE0001670D0 (fr) |
WO (1) | WO2001084146A2 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003530130A (ja) | 2000-04-14 | 2003-10-14 | メタボロン インコーポレイテッド | メタボロミクスを使用した薬物発見、疾患の処置、及び診断のための方法 |
US7329489B2 (en) | 2000-04-14 | 2008-02-12 | Matabolon, Inc. | Methods for drug discovery, disease treatment, and diagnosis using metabolomics |
DE10200374A1 (de) * | 2002-01-08 | 2003-07-24 | Friz Biochem Gmbh | Verfahren zur qualitativ und quantitativ vergleichenden Detektion chemischer Substanzen |
TWI375796B (en) | 2003-04-18 | 2012-11-01 | Becton Dickinson Co | Immuno-amplification |
US8304192B2 (en) | 2004-03-05 | 2012-11-06 | University Of Toledo | Methods and compositions for assessing nucleic acids and alleles |
US7476502B2 (en) | 2004-04-12 | 2009-01-13 | Willey James C | Methods and compositions for assaying analytes |
WO2006128010A2 (fr) * | 2005-05-26 | 2006-11-30 | The Trustees Of Boston University | Quantification d'acides nucleiques et de proteines au moyen d'etiquettes de masse d'oligonucleotides |
US8849577B2 (en) | 2006-09-15 | 2014-09-30 | Metabolon, Inc. | Methods of identifying biochemical pathways |
JP2009219388A (ja) * | 2008-03-14 | 2009-10-01 | Jsr Corp | イムノpcr用磁性粒子、標的物質の検出方法、および標的物質の検出キット |
AU2014248759B2 (en) * | 2013-03-13 | 2020-02-27 | Meso Scale Technologies, Llc. | Improved assay methods |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
AU2015259048B2 (en) | 2014-05-15 | 2021-09-09 | Meso Scale Technologies, Llc. | Improved assay methods |
AU2017370751B2 (en) | 2016-12-09 | 2023-11-09 | Ultivue, Inc. | Improved methods for multiplex imaging using labeled nucleic acid imaging agents |
US10246738B2 (en) | 2017-03-31 | 2019-04-02 | Ultivue, Inc. | DNA-antigen exchange and amplification |
US20210214776A1 (en) * | 2018-09-26 | 2021-07-15 | The University Of North Carolina At Chapel Hill | Compounds, compositions, and methods for improving assays |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996029432A1 (fr) * | 1995-03-22 | 1996-09-26 | Trustees Of Boston University | Procedes de detection de paracoccidioides |
DE19802576B4 (de) * | 1998-01-23 | 2004-10-28 | Xerion Pharmaceuticals Ag | Verfahren zur gleichzeitigen Identifizierung von Proteinen und ihren Bindungspartnern |
AU772069B2 (en) * | 1999-03-23 | 2004-04-08 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Protein isolation and analysis |
-
2000
- 2000-05-04 SE SE0001670A patent/SE0001670D0/xx unknown
-
2001
- 2001-05-04 AU AU2001258700A patent/AU2001258700A1/en not_active Abandoned
- 2001-05-04 WO PCT/IB2001/000957 patent/WO2001084146A2/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
SE0001670D0 (sv) | 2000-05-04 |
AU2001258700A1 (en) | 2001-11-12 |
WO2001084146A3 (fr) | 2002-04-11 |
WO2001084146A2 (fr) | 2001-11-08 |
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