WO2001083752A3 - 23949 and 32391, human ion channels and uses thereof - Google Patents

23949 and 32391, human ion channels and uses thereof Download PDF

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Publication number
WO2001083752A3
WO2001083752A3 PCT/US2001/013722 US0113722W WO0183752A3 WO 2001083752 A3 WO2001083752 A3 WO 2001083752A3 US 0113722 W US0113722 W US 0113722W WO 0183752 A3 WO0183752 A3 WO 0183752A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
expression vectors
ion channels
provides isolated
Prior art date
Application number
PCT/US2001/013722
Other languages
French (fr)
Other versions
WO2001083752A2 (en
Inventor
Maria A Glucksmann
Rory A J Curtis
Original Assignee
Millennium Pharm Inc
Maria A Glucksmann
Rory A J Curtis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria A Glucksmann, Rory A J Curtis filed Critical Millennium Pharm Inc
Priority to EP01930885A priority Critical patent/EP1280902A2/en
Priority to AU2001257378A priority patent/AU2001257378A1/en
Publication of WO2001083752A2 publication Critical patent/WO2001083752A2/en
Publication of WO2001083752A3 publication Critical patent/WO2001083752A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The invention provides isolated nucleic acid molecules, designated IC nucleic acid molecules, which encode novel IC-related ion channel molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing IC nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which an IC gene has been introduced or disrupted. The invention still further provides isolated IC proteins, fusion proteins, antigenic peptides and anti-IC antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/013722 2000-04-29 2001-04-27 23949 and 32391, human ion channels and uses thereof WO2001083752A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01930885A EP1280902A2 (en) 2000-04-29 2001-04-27 23949 and 32391, human ion channels and uses thereof
AU2001257378A AU2001257378A1 (en) 2000-04-29 2001-04-27 23949 and 32391, human ion channels and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20068900P 2000-04-29 2000-04-29
US60/200,689 2000-04-29

Publications (2)

Publication Number Publication Date
WO2001083752A2 WO2001083752A2 (en) 2001-11-08
WO2001083752A3 true WO2001083752A3 (en) 2002-09-06

Family

ID=22742760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/013722 WO2001083752A2 (en) 2000-04-29 2001-04-27 23949 and 32391, human ion channels and uses thereof

Country Status (3)

Country Link
EP (1) EP1280902A2 (en)
AU (1) AU2001257378A1 (en)
WO (1) WO2001083752A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020042100A1 (en) * 2000-07-03 2002-04-11 Chunhua Yan Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
UA79927C2 (en) * 2000-12-05 2007-08-10 Serono Genetics Inst Sa Polynucleotide, coding a polypeptide of potential-depending portal ionic human channel (canion), polypeptyde, antibody, method for identification of candidate modulator of canion-polypeptyde, method for treatment of bipolar disorder or schizophrenia and use of an antibody for production of drugs for treatment of schizophrenia or bipolar disorder
JPWO2002101035A1 (en) * 2001-05-10 2004-09-24 持田製薬株式会社 A novel voltage-gated cation channel protein
WO2003102156A2 (en) 2002-05-31 2003-12-11 Sloan-Kettering Institute For Cancer Research Heterologous stimulus-gated ion channels and methods of using same
AU2018373279A1 (en) 2017-11-27 2020-06-04 Coda Biotherapeutics, Inc. Compositions and methods for neurological diseases

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045437A2 (en) * 1997-04-10 1998-10-15 Genetics Institute, Inc. SECRETED EXPRESSED SEQUENCE TAGS (sESTs)
WO1999028342A2 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Low-voltage activated calcium channel compositions and methods
WO1999066041A1 (en) * 1998-06-16 1999-12-23 Human Genome Sciences, Inc. 94 human secreted proteins
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045437A2 (en) * 1997-04-10 1998-10-15 Genetics Institute, Inc. SECRETED EXPRESSED SEQUENCE TAGS (sESTs)
WO1999028342A2 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Low-voltage activated calcium channel compositions and methods
WO1999066041A1 (en) * 1998-06-16 1999-12-23 Human Genome Sciences, Inc. 94 human secreted proteins
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI Hinxton, UK; AGOSTINO ET AL., XP002187034 *
DATABASE EBI Hinxton, UK; ISOGAI ET AL., XP002186315 *
DATABASE EBI Hinxton, UK; OTA ET AL., XP002187026 *
DATABASE EBI Hinxton, UK; OTA ET AL., XP002187027 *
DATABASE EBI Hinxton, UK; RUBEN ET AL., XP002187025 *
DATABASE EBI Hinxton, UK; XP002186316 *
LEE J-H ET AL: "Cloning of a novel four repeat protein related to voltage-gated sodium and calcium channels", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 445, no. 2-3, 26 February 1999 (1999-02-26), pages 231 - 236, XP004259263, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO2001083752A2 (en) 2001-11-08
EP1280902A2 (en) 2003-02-05
AU2001257378A1 (en) 2001-11-12

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