WO2001081416A3 - Human ion channel and uses thereof - Google Patents

Human ion channel and uses thereof Download PDF

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Publication number
WO2001081416A3
WO2001081416A3 PCT/US2001/040608 US0140608W WO0181416A3 WO 2001081416 A3 WO2001081416 A3 WO 2001081416A3 US 0140608 W US0140608 W US 0140608W WO 0181416 A3 WO0181416 A3 WO 0181416A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
ion channel
expression vectors
provides isolated
Prior art date
Application number
PCT/US2001/040608
Other languages
French (fr)
Other versions
WO2001081416A2 (en
Inventor
Rory A J Curtis
Original Assignee
Millennium Pharm Inc
Rory A J Curtis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rory A J Curtis filed Critical Millennium Pharm Inc
Priority to AU2001253908A priority Critical patent/AU2001253908A1/en
Publication of WO2001081416A2 publication Critical patent/WO2001081416A2/en
Publication of WO2001081416A3 publication Critical patent/WO2001081416A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Abstract

The invention provides isolated nucleic acid molecules, designated IC47615 nucleic acid molecules, which encode novel IC47615-related ion channel molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing IC47615 nucleic acid molecules, host cells into which the expression vectors have been introduced, an nonhuman transgenic animals in which an IC47615 gene has been introduced or disrupted. The invention still further provides isolated IC47615 proteins, fusion proteins, antigenic peptides and anti-IC47615 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/040608 2000-04-26 2001-04-25 Human ion channel and uses thereof WO2001081416A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001253908A AU2001253908A1 (en) 2000-04-26 2001-04-25 47615, a novel human ion channel and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19979900P 2000-04-26 2000-04-26
US60/199,799 2000-04-26

Publications (2)

Publication Number Publication Date
WO2001081416A2 WO2001081416A2 (en) 2001-11-01
WO2001081416A3 true WO2001081416A3 (en) 2002-06-20

Family

ID=22739062

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/040608 WO2001081416A2 (en) 2000-04-26 2001-04-25 Human ion channel and uses thereof

Country Status (2)

Country Link
AU (1) AU2001253908A1 (en)
WO (1) WO2001081416A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0943683A1 (en) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0943683A1 (en) * 1998-03-10 1999-09-22 Smithkline Beecham Plc Human vanilloid receptor homologue Vanilrep1
EP1074617A2 (en) * 1999-07-29 2001-02-07 Helix Research Institute Primers for synthesising full-length cDNA and their use

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_EST [online] EMBL; 13 September 1999 (1999-09-13), NCI-CGAP: "EST", XP002185859, retrieved from EBI accession no. AW008521 Database accession no. AW008521 *
DATABASE EM_EST [online] EMBL; 22 July 1999 (1999-07-22), NCI-CGAP: "EST", XP002185860, retrieved from EBI accession no. AI860733 Database accession no. AI860733 *
DATABASE EM_HUM [online] EMBL; 4 August 1999 (1999-08-04), DOE JOINT GENOME INSTITUTE: "Homo spiens chromosome 19 clone CTC-526N19, complete sequence", XP002185861, retrieved from EBI accession no. AC008556 Database accession no. AC008556 *
ISHIBASHI KENICHI ET AL: "Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 270, no. 2, 13 April 2000 (2000-04-13), pages 370 - 376, XP002178968, ISSN: 0006-291X *
WALDMANN ET AL: "H+-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels", CURRENT OPINION IN NEUROBIOLOGY, LONDON, GB, vol. 8, no. 3, June 1998 (1998-06-01), pages 418 - 424, XP000864723, ISSN: 0959-4388 *

Also Published As

Publication number Publication date
WO2001081416A2 (en) 2001-11-01
AU2001253908A1 (en) 2001-11-07

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