WO2001075038A3 - A novel polypeptide - human atp- dependent serine protease 9 and the polynucleotide encoding said polypeptide - Google Patents

A novel polypeptide - human atp- dependent serine protease 9 and the polynucleotide encoding said polypeptide Download PDF

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Publication number
WO2001075038A3
WO2001075038A3 PCT/CN2001/000418 CN0100418W WO0175038A3 WO 2001075038 A3 WO2001075038 A3 WO 2001075038A3 CN 0100418 W CN0100418 W CN 0100418W WO 0175038 A3 WO0175038 A3 WO 0175038A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
serine protease
dependent serine
human atp
Prior art date
Application number
PCT/CN2001/000418
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001075038A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU56065/01A priority Critical patent/AU5606501A/en
Publication of WO2001075038A2 publication Critical patent/WO2001075038A2/en
Publication of WO2001075038A3 publication Critical patent/WO2001075038A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention disclosed a new kind of human ATP-dependent serine protease 9 and the polynucleotide encoding said polypeptide and aprocess for producing the polypeptide by recombinant methods. It also disclosed the method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathy, HIV infection, immune diseases and inflammation. The antagonist ofthe polypeptide and therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said human ATP-dependent serine protease 9.
PCT/CN2001/000418 2000-03-27 2001-03-26 A novel polypeptide - human atp- dependent serine protease 9 and the polynucleotide encoding said polypeptide WO2001075038A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU56065/01A AU5606501A (en) 2000-03-27 2001-03-26 A novel polypeptide, atp-dependant human hydrolase serine 9 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00115160A CN1315561A (en) 2000-03-27 2000-03-27 Polypeptide-human ATP-dependent serine protein hydrolase 9 and polynucleotide for coding it
CN00115160.6 2000-03-27

Publications (2)

Publication Number Publication Date
WO2001075038A2 WO2001075038A2 (en) 2001-10-11
WO2001075038A3 true WO2001075038A3 (en) 2002-04-18

Family

ID=4584629

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000418 WO2001075038A2 (en) 2000-03-27 2001-03-26 A novel polypeptide - human atp- dependent serine protease 9 and the polynucleotide encoding said polypeptide

Country Status (3)

Country Link
CN (1) CN1315561A (en)
AU (1) AU5606501A (en)
WO (1) WO2001075038A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0887414A2 (en) * 1997-06-09 1998-12-30 Smithkline Beecham Plc Human serine proteases HGBAB90
WO1999040183A1 (en) * 1998-02-06 1999-08-12 Human Genome Sciences, Inc. Human serine protease and serpin polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0887414A2 (en) * 1997-06-09 1998-12-30 Smithkline Beecham Plc Human serine proteases HGBAB90
WO1999040183A1 (en) * 1998-02-06 1999-08-12 Human Genome Sciences, Inc. Human serine protease and serpin polypeptides

Also Published As

Publication number Publication date
CN1315561A (en) 2001-10-03
WO2001075038A2 (en) 2001-10-11
AU5606501A (en) 2001-10-15

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