WO2001083758A3 - A novel polypeptide- human dihydroorotase 8 and the polynucleotide encoding said polypeptide - Google Patents

A novel polypeptide- human dihydroorotase 8 and the polynucleotide encoding said polypeptide Download PDF

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Publication number
WO2001083758A3
WO2001083758A3 PCT/CN2001/000637 CN0100637W WO0183758A3 WO 2001083758 A3 WO2001083758 A3 WO 2001083758A3 CN 0100637 W CN0100637 W CN 0100637W WO 0183758 A3 WO0183758 A3 WO 0183758A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
human dihydroorotase
discloses
novel
Prior art date
Application number
PCT/CN2001/000637
Other languages
French (fr)
Chinese (zh)
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WO2001083758A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Yumin Mao
Yi Xie
Shanghai Biowindow Gene Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Yumin Mao, Yi Xie, Shanghai Biowindow Gene Dev filed Critical Yumin Mao
Priority to AU67283/01A priority Critical patent/AU6728301A/en
Publication of WO2001083758A2 publication Critical patent/WO2001083758A2/en
Publication of WO2001083758A3 publication Critical patent/WO2001083758A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention discloses a new polypeptide-human dihydroorotase 8, the polynucleotide encoding said polypeptide, and a process for producing the polypeptide by recombinant DNA technology. It also discloses methods of applying the polypeptide for the treatment of various diseases, such as malignancy, hemopathy, HIV infection, immune disorders, and inflammation. This invention also discloses antagonist against said polypeptide and thereof therapy uses. In addition, it refers to the use of said polynucleotide encoding this new human dihydroorotase 8.
PCT/CN2001/000637 2000-04-29 2001-04-28 A novel polypeptide- human dihydroorotase 8 and the polynucleotide encoding said polypeptide WO2001083758A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU67283/01A AU6728301A (en) 2000-04-29 2001-04-28 A novel polypeptide- human dihydroorotase 8 and the polynucleotide encoding saidpolypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN 00115562 CN1321770A (en) 2000-04-29 2000-04-29 Novel polypeptide-human dihydroorotase 8 and polynucleotide for coding this polypeptide
CN00115562.8 2000-04-29

Publications (2)

Publication Number Publication Date
WO2001083758A2 WO2001083758A2 (en) 2001-11-08
WO2001083758A3 true WO2001083758A3 (en) 2002-04-25

Family

ID=4585008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000637 WO2001083758A2 (en) 2000-04-29 2001-04-28 A novel polypeptide- human dihydroorotase 8 and the polynucleotide encoding said polypeptide

Country Status (3)

Country Link
CN (1) CN1321770A (en)
AU (1) AU6728301A (en)
WO (1) WO2001083758A2 (en)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE PROTEIN [online] 8 February 1999 (1999-02-08), TANAKA T. ET AL., accession no. NCBI Database accession no. (BAA31090) *
DATABASE PROTEIN [online] 8 October 1999 (1999-10-08), ALM R.A. ET AL., accession no. NCBI Database accession no. (E71956) *

Also Published As

Publication number Publication date
AU6728301A (en) 2001-11-12
WO2001083758A2 (en) 2001-11-08
CN1321770A (en) 2001-11-14

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