WO2001075019A3 - A novel polypeptide - human ataxia - telangiectasia mutein 11 andthe polynucleotide encoding said polypeptide - Google Patents

A novel polypeptide - human ataxia - telangiectasia mutein 11 andthe polynucleotide encoding said polypeptide Download PDF

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Publication number
WO2001075019A3
WO2001075019A3 PCT/CN2001/000350 CN0100350W WO0175019A3 WO 2001075019 A3 WO2001075019 A3 WO 2001075019A3 CN 0100350 W CN0100350 W CN 0100350W WO 0175019 A3 WO0175019 A3 WO 0175019A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
mutein
telangiectasia
ataxia
Prior art date
Application number
PCT/CN2001/000350
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001075019A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Biowindow Gene Dev Inc
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biowindow Gene Dev Inc, Yumin Mao, Yi Xie filed Critical Biowindow Gene Dev Inc
Priority to AU50252/01A priority Critical patent/AU5025201A/en
Publication of WO2001075019A2 publication Critical patent/WO2001075019A2/en
Publication of WO2001075019A3 publication Critical patent/WO2001075019A3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention disclosed a new kind of human ataxia-telangiectasiamutein 11 and the polynucleotide encoding said polypeptide and a process for producing the polypeptide by recombinant methods. It also disclosed the method of applying the polypeptide for the treatment of various kinds of diseases, such as ataxia-telangeictasia, breast carcinoma, leucosis, leucoma, other kinds of tumor, immune disease, development disease, inflammation, hemopathy, HIV infection. The antagonist of the polypeptide and therapeutic use ofthe same is also disclosed. In addition, it refers to the use of polynucleotide encoding said human ataxia-telangiectasia mutein 11.
PCT/CN2001/000350 2000-03-22 2001-03-19 A novel polypeptide - human ataxia - telangiectasia mutein 11 andthe polynucleotide encoding said polypeptide WO2001075019A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU50252/01A AU5025201A (en) 2000-03-22 2001-03-19 A novel polypeptide, ataxia-telangiectasy human mutation protein 11 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00115059A CN1314409A (en) 2000-03-22 2000-03-22 New polypeptide-human ataxia-telangiectasia mutatioin protein 11 and polynucleotide for coding such polypeptide
CN00115059.6 2000-03-22

Publications (2)

Publication Number Publication Date
WO2001075019A2 WO2001075019A2 (en) 2001-10-11
WO2001075019A3 true WO2001075019A3 (en) 2002-06-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000350 WO2001075019A2 (en) 2000-03-22 2001-03-19 A novel polypeptide - human ataxia - telangiectasia mutein 11 andthe polynucleotide encoding said polypeptide

Country Status (3)

Country Link
CN (1) CN1314409A (en)
AU (1) AU5025201A (en)
WO (1) WO2001075019A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000572A2 (en) * 1992-06-22 1994-01-06 The Regents Of The University Of California Gene for ataxia-telangiectasia complementation group d (atdc)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000572A2 (en) * 1992-06-22 1994-01-06 The Regents Of The University Of California Gene for ataxia-telangiectasia complementation group d (atdc)

Also Published As

Publication number Publication date
WO2001075019A2 (en) 2001-10-11
AU5025201A (en) 2001-10-15
CN1314409A (en) 2001-09-26

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