WO2001074809A1 - Derives d'acylthiophene et leur utilisation en tant que medicaments - Google Patents

Derives d'acylthiophene et leur utilisation en tant que medicaments Download PDF

Info

Publication number
WO2001074809A1
WO2001074809A1 PCT/JP2001/002705 JP0102705W WO0174809A1 WO 2001074809 A1 WO2001074809 A1 WO 2001074809A1 JP 0102705 W JP0102705 W JP 0102705W WO 0174809 A1 WO0174809 A1 WO 0174809A1
Authority
WO
WIPO (PCT)
Prior art keywords
derivatives
acylthiophene
blood cells
drugs
salts
Prior art date
Application number
PCT/JP2001/002705
Other languages
English (en)
Japanese (ja)
Inventor
Yuji Sugawara
Hideki Kawai
Kiyoshi Okano
Yasumoto Adachi
Katsuyuki Mori
Original Assignee
Toray Industries, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries, Inc. filed Critical Toray Industries, Inc.
Publication of WO2001074809A1 publication Critical patent/WO2001074809A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés d'acylthiophène comprenant, généralement, le composé de formule (I), ou des sels de ceux-ci, acceptables au plan pharmaceutique. L'invention porte également sur des médicaments contenant lesdits dérivés ou sels en tant que principe actif. Lesdits dérivés induisent la production de plaquettes, de leucocytes, d'érythrocytes ou similaire, et sont utiles dans la chimiothérapie du cancer, la radiothérapie, la thérapie par greffe de moelle osseuse ou la pharmacothérapie ainsi que dans la prévention ou le traitement de la cytopénie consécutive à des troubles immunitaires, à l'anémie ou similaire.
PCT/JP2001/002705 2000-03-30 2001-03-30 Derives d'acylthiophene et leur utilisation en tant que medicaments WO2001074809A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000093610 2000-03-30
JP2000-093610 2000-03-30

Publications (1)

Publication Number Publication Date
WO2001074809A1 true WO2001074809A1 (fr) 2001-10-11

Family

ID=18608772

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2001/002705 WO2001074809A1 (fr) 2000-03-30 2001-03-30 Derives d'acylthiophene et leur utilisation en tant que medicaments

Country Status (1)

Country Link
WO (1) WO2001074809A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100348591C (zh) * 2004-07-15 2007-11-14 浙江海正集团有限公司 取代亚甲基吡喃酮类衍生物及其制备方法和用途
WO2011088152A1 (fr) 2010-01-12 2011-07-21 Portola Pharmaceuticals, Inc. Composition pharmaceutique et forme galénique de l'élinogrel et leurs méthodes d'application
CN1990478B (zh) * 2005-12-26 2011-08-31 浙江海正药业股份有限公司 6-芳基-3-取代亚甲基吡喃酮类化合物及其制备方法和用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0841063A1 (fr) * 1996-03-27 1998-05-13 Toray Industries, Inc. Derives de cetone et usage medicinal
EP0962456A1 (fr) * 1997-09-26 1999-12-08 Toray Industries, Inc. Derive de cetone et son utilisation en medecine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0841063A1 (fr) * 1996-03-27 1998-05-13 Toray Industries, Inc. Derives de cetone et usage medicinal
EP0962456A1 (fr) * 1997-09-26 1999-12-08 Toray Industries, Inc. Derive de cetone et son utilisation en medecine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100348591C (zh) * 2004-07-15 2007-11-14 浙江海正集团有限公司 取代亚甲基吡喃酮类衍生物及其制备方法和用途
CN1990478B (zh) * 2005-12-26 2011-08-31 浙江海正药业股份有限公司 6-芳基-3-取代亚甲基吡喃酮类化合物及其制备方法和用途
WO2011088152A1 (fr) 2010-01-12 2011-07-21 Portola Pharmaceuticals, Inc. Composition pharmaceutique et forme galénique de l'élinogrel et leurs méthodes d'application

Similar Documents

Publication Publication Date Title
NZ543661A (en) Pyrazolo-quinazoline derivatives having antitumor activity and process for their preparation
HK1053115A1 (en) Quinazoline derivatives for the treatment of tumours.
ES2187300A1 (es) Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos.
SG127738A1 (en) Heterocyclic compounds based on n6-substituted adenine, methods of their preparation, their use for preparation of drugs, pharmaceutical preparations containing these compounds
CY1110395T1 (el) Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
WO2004112711A3 (fr) Composition orale a liberation prolongee
MXPA06000302A (es) Derivados de pirazolil-indol activos como inhibidores de cinasa, procedimientos para su preparacion y composiciones farmaceuticas que los comprenden.
CA2386775A1 (fr) Medicaments de traitement de tumeurs malignes
EP1213026A4 (fr) Agents contenant du ginseng destines a proteger les cellules cerebrales ou les cellules nerveuses
NO20063277L (no) Farmasoytisk sammensetning av vinflunin som er ment for parenteral administrering, fremstillingsmate og anvendelse derav
HUP9900386A2 (hu) Fenoxi-piridin-származékok alkalmazása szívelégtelenség kezelésére alkalmas gyógyszerkészítmények előállítására
MY128014A (en) Thiol and thiocarbonyl derivatives which are useful as carboxypeptidase u inhibitors
WO2005014572A8 (fr) Derives de pyrimidylpyrrole pouvant etre utilises comme inhibiteurs de kinases
WO2002088100A3 (fr) 3-piperidinopropiophenones dopees et produits pharmaceutiques contenant ces composes
HK1068606A1 (en) Novel aminobenzoephenones
IT1226727B (it) Farmaci precursori della dopamina.
UA86776C2 (ru) Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
MY133112A (en) 3-amino-3-arylpropan-1-ol derivatives, and their preparation and use
HK1068348A1 (en) Therapeutic heterocycles as bradykinin b2 receptorantagonists
ATE326451T1 (de) Chinazolin derivate und therapeutische verwendungen davon
WO2001074809A1 (fr) Derives d'acylthiophene et leur utilisation en tant que medicaments
TW200612914A (en) Novel oxidized thioether derivatives, their manufacture and use as pharmaceutical agents
EP0962456A4 (fr) Derive de cetone et son utilisation en medecine
EP0980867A4 (fr) Derives de cetones et leur utilisation en medecine
WO2004073627A3 (fr) Methode et compositions therapeutiques pour administration topique

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA CN JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP